Chemistry, Pharmaceutical.
概要
| 作品: | 262 作品在 9 項出版品 9 種語言 | |
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書目資訊
Thermodynamics of pharmaceutical systems : = an introduction for students of pharmacy /
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Development of ligand assisted asymmetric synthetic methodology and synthetic progress toward AI-77-B.
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Studies in organic synthesis: Methodology, vitamin D analogs, and trioxane analogs.
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Catalytic, enantioselective alkylation of alpha-imino esters: The synthesis of nonnatural alpha-amino acid derivatives.
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Surface interaction, polarization and molecular weight effects for a whispering gallery mode sensor.
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Contributions of the GABA(A) receptor alpha(1) subunit to the structure and dynamics of the neurotransmitter binding pocket.
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The effects of indirubin derivatives on gene expression and cellular functions in the murine cell line, RAW 264.7.
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Bioanalytical methods for investigating bacterial adhesion and the antibacterial action of nitric oxide.
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Forward and reverse chemical genetic studies of transforming growth factor beta signaling.
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Effect of gel strength on drug release from swellable matrices through polymer erosion.
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Discovery and selection of crystal forms facilitated by polymer-induced heteronucleation.
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Syntheses and applications of bisphosphonate-based biomaterials and nanomaterials.
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Surface functionalized mesoporous silica nanoparticles for intracellular drug delivery.
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Development of a system for in-line drug content testing using near infrared reflectance spectroscopy.
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Isolation and characterization of lignan and secoiridoid glucosides from Schrebera alata.
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Design, synthesis, and biological evaluation of neo-tanshinlactone and its analogs as potent antibreast cancer agents.
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Molecular authentication of Epimedium species and the anti-osteoporosis effect of Herba Epimedii.
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Characterization of the interaction of the human sodium pump with naturally occurring and synthetic novel inhibitors.
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Transferrin and its oligomer: Intracellular processing and applications as drug carriers.
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Synthesis and evaluation of 2,3-dihydroquinazolinones as dual inhibitors of angiogenesis and cancer cell proliferation.
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Abaco Bush medicine: Essential oil composition of aromatic herbal medicines from Abaco Island, Bahamas.
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Total synthesis of DAQ-B1 and combinatorial synthesis of its analogues as potential anti-diabetic drugs.
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Total synthesis of luminacin D, isopanepoxydone, panepoxydone, and an isopanepoxydone derived biotinylated affinity reagent.
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Molecular mobility, physical stability, and transformation kinetics of amorphous and hydrated pharmaceutical solids.
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Ligand binding in human inosine 5'-monophosphate dehydrogenase type I and type II: Crystallographic and kinetic studies.
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Modular synthesis of annonaceous acetogenins and their activity against H-116 human solid colon tumor cells.
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Preclinical exploration of novel small molecules as anticancer agents in triple-negative and HER2/neu-positive breast cancers.
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Examining the interactive nature of cytochrome P450 3A4 and P-glycoprotein in intestinal drug metabolism.
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The detection, prevalence and properties of aggregate-based small molecule inhibition.
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Supercritical fluid technology for enhanced drug delivery and heterogeneous catalysis.
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Modular approach toward multifunctional nanoparticles for integrated drug delivery, targeting, and diagnostics: Synthetic methods and practical applications.
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Oligo-L-lysine-, dextran-, and alkyl- derivatives of polyethylenimine for the development of novel gene transfection vectors.
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Progress in the synthesis of sialic acid containing C-glycosides of potentially therapeutic carbohydrate epitopes.
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Do you speak genomics? Patenting biotechnology "Translation" inventions and other macromolecules.
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Theoretical aspects of designing new vaccines for breast cancer: Docking studies of peptide/HLA-A2.1 complexes.
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Pharmacophore fingerprint analysis of small molecules and proteins for virtual high throughput screening.
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Physical pharmacy : = physical chemical principles in the pharmaceutical sciences /
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Mechanistic studies of novel sodium channel blockers for the treatment of epilepsy.
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Bifunctional polymeric conjugates for contrast-enhanced magnetic resonance imaging-guided noninvasive photodynamic therapy of cancer.
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The design and delivery of a biodegradable poly(lactic-co-glycolic) acid based carrier to the regional lymphatics in rats.
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Synthesis and characterization of a squaraine dye-folate complex for photodynamic therapy.
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Colon-targeted delivery of 9-aminocamptothecin by HPMA copolymer conjugates for the treatment of colon cancer.
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Ocular delivery of peptide ganciclovir prodrugs following subconjunctival injection: Evaluation of episcleral drug delivery approach.
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In-vitro studies to improve microdialysis recovery of a lipophilic drug: Ketoconazole.
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Design and synthesis of bioactive small molecules and high-throughput identification of enantiomeric excess.
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Design and synthesis of small molecules and nanoparticle conjugates for cell type-selective delivery.
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The reaction kinetics, crystal structures and novel inhibitors of bacterial OSB-CoA synthetase.
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Identification and design of small molecules that associate with aggregated Alzheimer's-related beta-amyloid peptides.
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Cellular uptake of cobalamin in clinically-derived blood samples, normal and cancerous brain cells.
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Elucidation of anti-proliferative and pro-apoptotic signaling induced by the immunomodulatory benzodiazepine Bz-423.
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Computational studies of the metal-binding proteins stromelysin-1 and human serum transferrin: Protein modeling and inhibitor design.
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From capillary to microchip electrophoresis: Electrochemical detection of peptides.
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Drug permeability across the buccal mucosa: Role of ionized species activity and development of a predictive model.
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MefA-mediated macrolide resistance in group A streptococci: The search for efflux pump inhibitors from marine natural products.
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Biosynthesis and engineering of anticancer antibiotics fredericamycin from Streptomyces griseus and leinamycin from Streptomyces atroolivaceus.
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Improving blood brain barrier permeation of small molecules exhibiting chemotherapeutic and neuroprotective effects.
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A mechanism of resistance and mode of action for drugs against Plasmodium falciparum.
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Sequence determinants and inhibition of the aggregation of the Alzheimer's Abeta peptide.
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From imitation to innovation: The role of patent in China's biotechnology and pharmaceutical industries.
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Physicochemical characterization of camptothecin membrane binding properties and polymeric microsphere formulations.
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Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula.
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New methods for catalytic enantioselective conjugate addition of dialkylzinc reagents to alpha,beta-unsaturated carbonyls: Discovery and use of new catalysts.
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Drug candidate discovery by high-throughput virtual screening of protein binding sites.
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Preservation of two therapeutic biopharmaceuticals using sugars and polymers: Hematopoietic stem and progenitor cells and a live attenuated viral vaccine.
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I. The nature of fluorine-mediated intermolecular interactions. II. The fluorophobic effect as a force for molecular recognition and self-assembly.
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Design, synthesis, characterization and drug release kinetics of PAMAM dendrimer based drug formulations.
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Improvement in the bioavailability of poorly water-soluble drugs via pulmonary delivery of nanoparticles.
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Therapeutic antibody formulation: Phase behavior, opalescence, viscosity, physical and chemical stability.
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Enantioselective tandem cyclopropanation/Cope rearrangement of heteroaryldiazoacetates and their applications in natural product synthesis.
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Self-assembled Rosette Nanotubes for Drug Delivery and Bone/Cartilage Tissue Regeneration.
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Design and development of a rupturable drug delivery system for delivering drug to the distal gastrointestinal tract-colon.
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The direct and indirect effects of herbal products on common drug metabolizing enzymes and drug transporters.
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Development of multivalent inhibitors for two protein-protein interactions associated with human leukemia.
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Non-photochemical light-induced nucleation and control of polymorphism through polarization-switching.
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Determination of an empirical correlation for the mass transfer coefficients of pharmaceutical powders in a fluid bed dryer.
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Optimization of drying-end-points measurements for the automation of a fluidized-bed dryer using FT-NIR spectroscopy.
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Development of fluorescent/stable isotope tagging strategies for proteins containing DOPA.
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Nifedipine solid dispersion in microparticles of ethylcellulose and Eudragit RL binary blend for drug controlled delivery .
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Protein-based hydrogels self-assembled from genetically engineered triblock polypeptides containing coiled-coil domains.
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Implementation and evaluation of a molecular strategy for delivery of nucleic acid based therapeutics.
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Effects of formulation and processing stress on the physical stability of protein solutions.
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Novel approaches to assess the efficacy and toxicity of intestinal absorption enhancers.
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3D-QSAR of anti-mitotic, tubulin binding analogs using comparative molecular field analysis (CoMFA).
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Development and validation of in vitro screening procedure for identifying herbals possessing sulfonylurea-like activity.
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The rational design of chiral alkyl dihaloboranes and their use as asymmetric Diels-Alder catalysts.
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Electrochemical stability of insulin and stabilization for iontophoretic transdermal delivery.
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Bioavailability of the tea flavonoids epicatechin and epicatechin gallate: Role of membrane transport and metabolism.
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Development and application of LC/MS and MS/MS methods for the structural characterization of flavonoid glycosides.
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Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria.
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I. X-ray crystal structure of the MurG:UDP-GlcNAc cocomplex. II. High throughput screening of Escherichia coli MurG.
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Design, development and utilization of novel TAE descriptors and machine learning methods.
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Introduction of structural perturbations into drug polymers: Effect on enzyme hydrolysis.
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Inhibiting bacterial transglycosylases: From small molecules to a library of vancomycin analogs.
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Design, synthesis, and evaluation of potent androgen receptor targeted prodrugs of doxorubicin.
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Chemical modifications for improvement of the pharmacological properties of therapeutic agents.
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An introduction to pharmaceutical sciences = production, chemistry, techniques and technology /
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Skin aging handbook = an integrated approach to biochemistry and product development /
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Quantification and identification of pharmaceuticals and their treatment by-products in drinking water and wastewater by LC/MS/MS.
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Assessment of the occurrence and potential risks of pharmaceuticals and their metabolites in fish and water using liquid chromatography mass spectrometry.
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Human exposure to indoor organic contaminants, with emphasis on novel brominated flame retardants.
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Affinity chromatographic studies of drug-protein binding in personalized medicine.
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Serum pharmacochemistry of traditional Chinese medicine = technologies, strategies and applications /
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Novel utilization of transition metal organometallic chemistry for the synthesis of natural products.
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