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The effect of consumption of differe...

Light, Heather.

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The effect of consumption of different sugar-sweetened beverages on the development of obesity and related metabolic disorders in young female rats.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	The effect of consumption of different sugar-sweetened beverages on the development of obesity and related metabolic disorders in young female rats./
Author:	Light, Heather.
Description:	87 p.
Notes:	Adviser: Janet C. L. Tou.
Contained By:	Masters Abstracts International46-04.
Subject:	Health Sciences, Nutrition. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1451719
ISBN:	9780549433033

The effect of consumption of different sugar-sweetened beverages on the development of obesity and related metabolic disorders in young female rats.
Light, Heather.

The effect of consumption of different sugar-sweetened beverages on the development of obesity and related metabolic disorders in young female rats. - 87 p.

Adviser: Janet C. L. Tou.

Thesis (M.S.)--West Virginia University, 2007.

The consumption of sugar-sweetened beverages particularly, high fructose corn syrup (HFCS), by adolescents has increased. The substitution of sucrose (50:50 glucose: fructose) by HFCS-55 (45:55 glucose: fructose) has been suggested to promote weight gain based on the observation that as intake of HFCS-55 sweetened beverages has increased so has the rate of obesity. Despite gaps in the existing knowledge regarding the health implication of increased fructose intake, the more cheaply produced HFCS-55 has replaced sucrose as the main sweetener added to beverages. The objective of this study was to determine the effect of consumption of HFCS-55 compared to other sugar-sweetened beverages on the development of obesity and obesity-related metabolic disorders.

ISBN: 9780549433033Subjects--Topical Terms:

1017801
Health Sciences, Nutrition.

The effect of consumption of different sugar-sweetened beverages on the development of obesity and related metabolic disorders in young female rats.
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005 20110622
008 110622s2007 ||||||||||||||||| ||eng d
020 $a 9780549433033
035 $a (UMI)AAI1451719
035 $a AAI1451719
040 $a UMI $c UMI
100 1 $a Light, Heather. $3 1278353
245 1 4 $a The effect of consumption of different sugar-sweetened beverages on the development of obesity and related metabolic disorders in young female rats.
300 $a 87 p.
500 $a Adviser: Janet C. L. Tou.
500 $a Source: Masters Abstracts International, Volume: 46-04, page: 2089.
502 $a Thesis (M.S.)--West Virginia University, 2007.
520 $a The consumption of sugar-sweetened beverages particularly, high fructose corn syrup (HFCS), by adolescents has increased. The substitution of sucrose (50:50 glucose: fructose) by HFCS-55 (45:55 glucose: fructose) has been suggested to promote weight gain based on the observation that as intake of HFCS-55 sweetened beverages has increased so has the rate of obesity. Despite gaps in the existing knowledge regarding the health implication of increased fructose intake, the more cheaply produced HFCS-55 has replaced sucrose as the main sweetener added to beverages. The objective of this study was to determine the effect of consumption of HFCS-55 compared to other sugar-sweetened beverages on the development of obesity and obesity-related metabolic disorders.
520 $a Young (age 28 days) female Sprague-Dawley rats were randomized into treatment groups consisting of deionized distilled water (ddH2O) sweetened with sugars at the levels typically found in soft drinks of 13% w/v as either: (1) Glucose; (2) Sucrose; (3) Fructose; (4) HFCS-55 or (5) Control (no sugar). Rats were given ad libitum access to their assigned sweetened beverages for 8 weeks.
520 $a Rats provided HFCS-55 beverages had higher (P<0.05) final body weight and fat pad (retroperitoneal and gonadal) weights compared to rats drinking the glucose sweetened beverages and control animals. A negative correlation (r2=0.89, P<0.05) between food intake and beverage consumption suggested that rats compensated for additional calories provided by beverages by decreasing food intake. Increased fat mass was not associated with substantial differences in adipose tissue function indicated by no significant differences in LPL or PPARgamma mRNA abundance in the gonadal adipose tissue. Increased adiposity did not result in metabolic variables indicated by the absence of significant difference in the serum lipid and lipoprotein profile, fasting serum glucose, leptin, insulin, or C-peptide levels from control animals.
520 $a The study results showed that consumption of HFCS-55 sweetened beverages resulted in greater adiposity compared to the other sweeteners. Thus, the addition of HFCS-55 to food products may be an important contributing dietary factor to the increase prevalence of obesity.
590 $a School code: 0256.
650 4 $a Health Sciences, Nutrition. $3 1017801
690 $a 0570
710 2 $a West Virginia University. $3 1017532
773 0 $t Masters Abstracts International $g 46-04.
790 $a 0256
790 1 0 $a Tou, Janet C. L., $e advisor
791 $a M.S.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1451719