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Population genetic approaches to the...

The University of Chicago.

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Population genetic approaches to the study of speciation.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Population genetic approaches to the study of speciation./
作者:	Becquet, Celine.
面頁冊數:	212 p.
附註:	Adviser: Molly Przeworski.
Contained By:	Dissertation Abstracts International69-07B.
標題:	Biology, Bioinformatics. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3322562
ISBN:	9780549739654

Population genetic approaches to the study of speciation.
Becquet, Celine.

Population genetic approaches to the study of speciation. - 212 p.

Adviser: Molly Przeworski.

Thesis (Ph.D.)--The University of Chicago, 2008.

The mechanisms of speciation still escape our full understanding despite over a century of research. Here, I take a population genetic approach to learn about the processes by which populations diverge and eventually become distinct species, illustrating its application in fields varying from conservation biology to human evolution. As a background to the dissertation, I present in Chapter 1 the state of research in these fields at the time I started my PhD and provide brief introductions to the projects described in the thesis. In Chapter 2, I use extensive variation data from multiple loci to unravel the complex relationships and evolutionary history of chimpanzee species and subspecies. In Chapter 3, I introduce a computational approach, MIMAR , which uses summary statistics of polymorphism at multiple independently-evolving loci and allows for intra-locus recombination to estimate the parameters of simple speciation models. I apply this method to data from the species and subspecies of chimpanzee, refining and completing the results of Chapter 2, as well as from the other non-human ape species and populations. In Chapter 4, I study the behavior of my and related computational methods when data are generated under realistic deviations from the simple models considered to date. This work underscores the limitation of computational approaches in resolving the question of whether the early stages of speciation can occur in the presence of gene flow. Finally in Chapter 5, I use my method to learn more about the demographic history of six human populations.

ISBN: 9780549739654Subjects--Topical Terms:

1018415
Biology, Bioinformatics.

Population genetic approaches to the study of speciation.
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