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Rapid effects of 25-hydroxyvitamin D...

Phadnis, Ruta Rajan.

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Rapid effects of 25-hydroxyvitamin D3 on calcium uptake in chick enterocytes.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Rapid effects of 25-hydroxyvitamin D3 on calcium uptake in chick enterocytes./
Author:	Phadnis, Ruta Rajan.
Description:	53 p.
Notes:	Source: Masters Abstracts International, Volume: 42-01, page: 0213.
Contained By:	Masters Abstracts International42-01.
Subject:	Health Sciences, Nutrition. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1415142

Rapid effects of 25-hydroxyvitamin D3 on calcium uptake in chick enterocytes.
Phadnis, Ruta Rajan.

Rapid effects of 25-hydroxyvitamin D3 on calcium uptake in chick enterocytes. - 53 p.

Source: Masters Abstracts International, Volume: 42-01, page: 0213.

Thesis (M.S.)--Utah State University, 2003.

This study investigates the potential biological activity of 25(OH)D 3 considered to be an inactive vitamin D3 metabolite. In isolated enterocytes 25(OH)D3 within 1 min decreased 45 Ca uptake to 54% of the controls. The enterocytes exhibited a biphasic dose response curve for 25(OH)D3-stimulated calcium uptake and 24,25(OH)2D3 inhibited the stimulation. Increasing age decreased response to 25(OH)D3 stimulated calcium uptake in isolated epithelial cells. BAY K8644, protein kinase A (PKA) activator forskolin, and phorbol ester treatment enhanced levels of 45Ca at T = 10 min (each, P < 0.05). 25(OH)D3 increased PKA activity above corresponding controls at T = 1 min (89.8%, P < 0.05) and T = 3 min (78.4%). No evidence for the activation of PKC by 25(OH)D3 was found.Subjects--Topical Terms:

1017801
Health Sciences, Nutrition.

Rapid effects of 25-hydroxyvitamin D3 on calcium uptake in chick enterocytes.
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008 130614s2003 eng d
035 $a (UnM)AAI1415142
035 $a AAI1415142
040 $a UnM $c UnM
100 1 $a Phadnis, Ruta Rajan. $3 1948458
245 1 0 $a Rapid effects of 25-hydroxyvitamin D3 on calcium uptake in chick enterocytes.
300 $a 53 p.
500 $a Source: Masters Abstracts International, Volume: 42-01, page: 0213.
500 $a Major Professor: Ilka Nemere.
502 $a Thesis (M.S.)--Utah State University, 2003.
520 $a This study investigates the potential biological activity of 25(OH)D 3 considered to be an inactive vitamin D3 metabolite. In isolated enterocytes 25(OH)D3 within 1 min decreased 45 Ca uptake to 54% of the controls. The enterocytes exhibited a biphasic dose response curve for 25(OH)D3-stimulated calcium uptake and 24,25(OH)2D3 inhibited the stimulation. Increasing age decreased response to 25(OH)D3 stimulated calcium uptake in isolated epithelial cells. BAY K8644, protein kinase A (PKA) activator forskolin, and phorbol ester treatment enhanced levels of 45Ca at T = 10 min (each, P < 0.05). 25(OH)D3 increased PKA activity above corresponding controls at T = 1 min (89.8%, P < 0.05) and T = 3 min (78.4%). No evidence for the activation of PKC by 25(OH)D3 was found.
590 $a School code: 0241.
650 4 $a Health Sciences, Nutrition. $3 1017801
650 4 $a Biology, Cell. $3 1017686
650 4 $a Chemistry, Biochemistry. $3 1017722
690 $a 0570
690 $a 0379
690 $a 0487
710 2 0 $a Utah State University. $3 960049
773 0 $t Masters Abstracts International $g 42-01.
790 1 0 $a Nemere, Ilka, $e advisor
790 $a 0241
791 $a M.S.
792 $a 2003
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1415142