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Nutritional status of postmenopausal...

Woolf, Kathleen.

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Nutritional status of postmenopausal women with and without rheumatoid arthritis.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Nutritional status of postmenopausal women with and without rheumatoid arthritis./
作者:	Woolf, Kathleen.
面頁冊數:	158 p.
附註:	Chair: Melinda Manore.
Contained By:	Dissertation Abstracts International63-06B.
標題:	Health Sciences, Nutrition. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3057423
ISBN:	9780493727363

Nutritional status of postmenopausal women with and without rheumatoid arthritis.
Woolf, Kathleen.

Nutritional status of postmenopausal women with and without rheumatoid arthritis. - 158 p.

Chair: Melinda Manore.

Thesis (Ph.D.)--Arizona State University, 2002.

Rheumatoid arthritis (RA), a chronic, inflammatory connective-tissue disorder, increases the risk for poor nutritional status as well as osteoporosis and cardiovascular disease (CVD). This research examined nutritional status and bone health of postmenopausal women with RA as compared to women without RA (HC).

ISBN: 9780493727363Subjects--Topical Terms:

1017801
Health Sciences, Nutrition.

Nutritional status of postmenopausal women with and without rheumatoid arthritis.
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100 1 $a Woolf, Kathleen. $3 1288313
245 1 0 $a Nutritional status of postmenopausal women with and without rheumatoid arthritis.
300 $a 158 p.
500 $a Chair: Melinda Manore.
500 $a Source: Dissertation Abstracts International, Volume: 63-06, Section: B, page: 2793.
502 $a Thesis (Ph.D.)--Arizona State University, 2002.
520 $a Rheumatoid arthritis (RA), a chronic, inflammatory connective-tissue disorder, increases the risk for poor nutritional status as well as osteoporosis and cardiovascular disease (CVD). This research examined nutritional status and bone health of postmenopausal women with RA as compared to women without RA (HC).
520 $a Chapter one reviews the literature on nutrition, exercise, and RA. Chapter two reports the nutritional status (folate, vitamin B12, vitamin B6, riboflavin) of RA and HC women. No significant differences existed for dietary intake; however, nutrient intakes were not optimal. Due to the extensive use of supplements (80--87% of subjects), results showed no significant differences between groups for blood nutrient parameters. Among subjects not using supplemental B6, pyridoxal 5'phosphate (PLP) was significantly lower in RA subjects compared to HC. Vitamin supplements helped maintain nutritional status despite inadequate dietary intakes. Due to the high supplement use, the study was unable to examine the impact of RA on folate, B12, B6, or riboflavin status.
520 $a Chapter three reports measures of bone health, dietary intakes, and physical activity in RA and HC women. Energy, macronutrient, and calcium intakes were similar between groups but RA subjects consumed less vitamin C, vitamin D, and magnesium. Total alkaline phosphatase was elevated in women with RA; no differences were seen between groups for serum osteocalcin, estradiol, bone mineral density, or physical activity patterns. Subjects in both groups exhibited osteopenia and osteoporosis, thus, bone health should be monitored in all older women.
520 $a Individuals with RA have an increased risk of CVD and elevated plasma homocysteine is an independent risk factor for CVD. Chapter four reports plasma homocysteine and folate, vitamin B12, and vitamin B6 status in nonsupplementing RA and HC women. Plasma homocysteine was significantly higher and PLP concentrations significantly lower in RA versus HC women. Poor vitamin B6 status and elevated plasma homocysteine may explain why individuals with RA have an increased risk of CVD.
520 $a In conclusion, identifying populations at risk for poor nutritional status, such as individuals with RA, and making nutritional recommendations to reduce chronic disease, such as osteoporosis or CVD, is an important area of nutrition and is becoming more critical as our population ages.
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791 $a Ph.D.
792 $a 2002
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