語系:
繁體中文
English
說明(常見問題)
回圖書館首頁
手機版館藏查詢
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
Health-related fitness, physical act...
~
Krasnoff, Joanne B.
FindBook
Google Book
Amazon
博客來
Health-related fitness, physical activity, and non-alcoholic fatty liver disease.
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Health-related fitness, physical activity, and non-alcoholic fatty liver disease./
作者:
Krasnoff, Joanne B.
面頁冊數:
408 p.
附註:
Adviser: Janet P. Wallace.
Contained By:
Dissertation Abstracts International68-07B.
標題:
Biology, Physiology. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3274261
ISBN:
9780549151357
Health-related fitness, physical activity, and non-alcoholic fatty liver disease.
Krasnoff, Joanne B.
Health-related fitness, physical activity, and non-alcoholic fatty liver disease.
- 408 p.
Adviser: Janet P. Wallace.
Thesis (Ph.D.)--Indiana University, 2007.
Nonalcoholic fatty liver disease (NAFLD) has been referred to as the hepatic manifestation of the metabolic syndrome (MS). There is a lower prevalence of MS in individuals with higher health-related fitness (HRF) and physical activity (PA) participation. The relationship between NAFLD severity and HRF and PA is unknown. The purpose of this study was to document and compare measures of HRF and PA in patients with a histological spectrum of NAFLD. Thirty-seven patients with liver biopsy confirmed-NAFLD (18F/19M; age = 45.9 +/- 12.7 yr) completed assessment of cardiorespiratory fitness (CRF, VO2peak), muscle strength (quadriceps peak torque), and body composition (%fat). Current and historical PA was also assessed. Liver histology classified NAFLD severity by steatosis (mild, moderate, severe), fibrosis stage (stage 1 vs. stage 2/3), necroinflammatory activity (NAFLD Activity Score; ≤ 4, NAS1 vs. ≥ 5, NAS2) and diagnosis of nonalcoholic steatohepatitis by Brunt criteria (NASH vs. NotNASH). ANOVA and independent t-tests were used to determine the differences among the various groups. Less than 20% of the patients met recommended guidelines for PA and 97.3% were classified as increased risk of morbidity and mortality by %fat. No differences were detected in VO2peak (x=26.8 +/- 7.4 ml/kg/min) or %fat (x=38.6 +/- 8.2%) among the steatosis or fibrosis groups. Peak VO2 was higher in the NAS1 vs. NAS2 (p=0.013) and notNASH vs. the NASH (p= 0.048). Patients with NAFLD of differing severity have sub-optimal HRF. CRF was significantly worse in those with NASH and greater NAS. Lifestyle interventions to improve HRF may be beneficial in reducing the associated risk factors and preventing progression of NAFLD.
ISBN: 9780549151357Subjects--Topical Terms:
1017816
Biology, Physiology.
Health-related fitness, physical activity, and non-alcoholic fatty liver disease.
LDR
:02612nam 2200277 a 45
001
955092
005
20110622
008
110622s2007 eng d
020
$a
9780549151357
035
$a
(UMI)AAI3274261
035
$a
AAI3274261
040
$a
UMI
$c
UMI
100
1
$a
Krasnoff, Joanne B.
$3
1278552
245
1 0
$a
Health-related fitness, physical activity, and non-alcoholic fatty liver disease.
300
$a
408 p.
500
$a
Adviser: Janet P. Wallace.
500
$a
Source: Dissertation Abstracts International, Volume: 68-07, Section: B, page: 4315.
502
$a
Thesis (Ph.D.)--Indiana University, 2007.
520
$a
Nonalcoholic fatty liver disease (NAFLD) has been referred to as the hepatic manifestation of the metabolic syndrome (MS). There is a lower prevalence of MS in individuals with higher health-related fitness (HRF) and physical activity (PA) participation. The relationship between NAFLD severity and HRF and PA is unknown. The purpose of this study was to document and compare measures of HRF and PA in patients with a histological spectrum of NAFLD. Thirty-seven patients with liver biopsy confirmed-NAFLD (18F/19M; age = 45.9 +/- 12.7 yr) completed assessment of cardiorespiratory fitness (CRF, VO2peak), muscle strength (quadriceps peak torque), and body composition (%fat). Current and historical PA was also assessed. Liver histology classified NAFLD severity by steatosis (mild, moderate, severe), fibrosis stage (stage 1 vs. stage 2/3), necroinflammatory activity (NAFLD Activity Score; ≤ 4, NAS1 vs. ≥ 5, NAS2) and diagnosis of nonalcoholic steatohepatitis by Brunt criteria (NASH vs. NotNASH). ANOVA and independent t-tests were used to determine the differences among the various groups. Less than 20% of the patients met recommended guidelines for PA and 97.3% were classified as increased risk of morbidity and mortality by %fat. No differences were detected in VO2peak (x=26.8 +/- 7.4 ml/kg/min) or %fat (x=38.6 +/- 8.2%) among the steatosis or fibrosis groups. Peak VO2 was higher in the NAS1 vs. NAS2 (p=0.013) and notNASH vs. the NASH (p= 0.048). Patients with NAFLD of differing severity have sub-optimal HRF. CRF was significantly worse in those with NASH and greater NAS. Lifestyle interventions to improve HRF may be beneficial in reducing the associated risk factors and preventing progression of NAFLD.
590
$a
School code: 0093.
650
4
$a
Biology, Physiology.
$3
1017816
650
4
$a
Health Sciences, Recreation.
$3
1018003
690
$a
0575
690
$a
0719
710
2
$a
Indiana University.
$b
School of Health, Physical Education and Recreation.
$3
1018026
773
0
$t
Dissertation Abstracts International
$g
68-07B.
790
$a
0093
790
1 0
$a
Wallace, Janet P.,
$e
advisor
791
$a
Ph.D.
792
$a
2007
856
4 0
$u
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3274261
筆 0 讀者評論
館藏地:
全部
電子資源
出版年:
卷號:
館藏
1 筆 • 頁數 1 •
1
條碼號
典藏地名稱
館藏流通類別
資料類型
索書號
使用類型
借閱狀態
預約狀態
備註欄
附件
W9119528
電子資源
11.線上閱覽_V
電子書
EB W9119528
一般使用(Normal)
在架
0
1 筆 • 頁數 1 •
1
多媒體
評論
新增評論
分享你的心得
Export
取書館
處理中
...
變更密碼
登入