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Reducing prescription drug abuse by ...

Coleman, John J.

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Reducing prescription drug abuse by design.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Reducing prescription drug abuse by design./
作者:	Coleman, John J.
面頁冊數:	352 p.
附註:	Adviser: Susan J. Tolchin.
Contained By:	Dissertation Abstracts International68-03B.
標題:	Health Sciences, Pharmacy. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3255787

Reducing prescription drug abuse by design.
Coleman, John J.

Reducing prescription drug abuse by design. - 352 p.

Adviser: Susan J. Tolchin.

Thesis (Ph.D.)--George Mason University, 2007.

According a recent government report, the nonmedical use of prescription drugs is the second most prevalent form of illicit drug abuse in the U.S. today. Nonmedical use of lawfully manufactured drugs is estimated to cost the American economy more than Subjects--Topical Terms:

1017737
Health Sciences, Pharmacy.

Reducing prescription drug abuse by design.
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100 1 $a Coleman, John J. $3 1273651
245 1 0 $a Reducing prescription drug abuse by design.
300 $a 352 p.
500 $a Adviser: Susan J. Tolchin.
500 $a Source: Dissertation Abstracts International, Volume: 68-03, Section: B, page: 1585.
502 $a Thesis (Ph.D.)--George Mason University, 2007.
520 $a According a recent government report, the nonmedical use of prescription drugs is the second most prevalent form of illicit drug abuse in the U.S. today. Nonmedical use of lawfully manufactured drugs is estimated to cost the American economy more than $2 00 billion annually. Supply-side regulatory measures developed almost a century ago appear ineffective today for controlling this form of drug abuse and may even impinge upon healthcare. In this study, we examine a theory for reducing prescription drug abuse by employing abuse-resistant technology in the composition and design of abusable drugs. We test this hypothesis by comparing estimated abuse levels for drugs containing the same active ingredient but using different design characteristics, including some that appear to inhibit abuse. Results: In every instance, drugs employing abuse-resistant designs showed significantly lower estimated abuse levels than comparator drugs without such designs. In addition, recommendations for implementing suggested regulatory policy changes are presented and discussed.
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