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Polymeric micro/nanofibers: Fabricat...

Nain, Amrinder Singh.

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Polymeric micro/nanofibers: Fabrication, aligned deposition, mechanical characterization, and biological applications.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Polymeric micro/nanofibers: Fabrication, aligned deposition, mechanical characterization, and biological applications./
作者:	Nain, Amrinder Singh.
面頁冊數:	264 p.
附註:	Source: Dissertation Abstracts International, Volume: 68-09, Section: B, page: 6256.
Contained By:	Dissertation Abstracts International68-09B.
標題:	Biophysics, Medical. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3282365
ISBN:	9780549241768

Polymeric micro/nanofibers: Fabrication, aligned deposition, mechanical characterization, and biological applications.
Nain, Amrinder Singh.

Polymeric micro/nanofibers: Fabrication, aligned deposition, mechanical characterization, and biological applications. - 264 p.

Source: Dissertation Abstracts International, Volume: 68-09, Section: B, page: 6256.

Thesis (Ph.D.)--Carnegie Mellon University, 2007.

Precise manufacturing of nanofibers is an essential bottom-up manufacturing technique in nano environment and polymeric micro/nanofibers offer several advantages over other materials. In this work, we have developed two techniques for repeatable fabrication of precisely aligned polymeric fibers of polystyrene (PS) and poly (methyl methacrylate) (PMMA) with diameters ranging from sub 50 nm to few microns and several millimeters in length. For the first time, dependency of properties of the fabricated micro/nanofibers on solution rheological properties and molecular weight are mapped in accordance with theoretical predictions. Mechanical properties of the deposited aligned fibers, as small as 34 nm in diameter, with fixed-fixed boundary conditions are characterized using state-of-the-art atomic force microscopy and electron microscopy. Resonance frequency measurements of the deposited fibers are in agreement with analytical models and are shown to estimate the Young's modulus of sub-micron fibers. Finally, Spinneret based Tunable Engineered Parameters (STEP) technique has been developed for fabricating single and multi-layer biomaterial scaffolds. Scaffolds are successfully seeded with mouse pluripotential cells for tissue engineering applications and the geometrical constraints of diverging fibers in single layer scaffolds and intersecting fibers (right angle) have provided new insights into cellular dynamics and the design of future aligned biomaterial scaffolds.

ISBN: 9780549241768Subjects--Topical Terms:

1017681
Biophysics, Medical.

Polymeric micro/nanofibers: Fabrication, aligned deposition, mechanical characterization, and biological applications.
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