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Ultrasound and exercise in skeletal ...

Markert, Chad D.

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Ultrasound and exercise in skeletal muscle regeneration.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Ultrasound and exercise in skeletal muscle regeneration./
作者:	Markert, Chad D.
面頁冊數:	53 p.
附註:	Adviser: Steven T. Devor.
Contained By:	Dissertation Abstracts International65-07B.
標題:	Biology, Animal Physiology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3141671
ISBN:	9780496887514

Ultrasound and exercise in skeletal muscle regeneration.
Markert, Chad D.

Ultrasound and exercise in skeletal muscle regeneration. - 53 p.

Adviser: Steven T. Devor.

Thesis (Ph.D.)--The Ohio State University, 2004.

Objective. To determine whether non-thermal therapeutic ultrasound (US) and low-intensity exercise (Ex) influence skeletal muscle regeneration following a standardized contusion injury in an animal model. Hypothesis. Compared with the three other contusion injured treatment groups, which received exercise treatment alone (Ex+NoUS), ultrasound treatment alone (NoEx+US), and no treatment (NoEx+NoUS), the Ex+US group will exhibit an increase in measures of skeletal muscle regeneration. Design. Randomized control trial with blinded comparisons in a 2 x 2 factorial (ultrasound X exercise) design. Setting. Animal care facility/exercise physiology biochemistry laboratory. Participants. Twenty male Wistar rats (8 mo.) received a reproducible bilateral contusion injury to the gastrocnemius (GTN) muscles. Interventions. Ultrasound (parameters = 3 MHz, 0.1 W/cm2, 1cm2 transducer, 5 min duration/day) and exercise (20 min/day of low-intensity treadmill walking at 14 m/min). Main outcome measures. 96 hour post-injury muscle mass, contractile protein concentration, fiber cross-sectional area (CSAf), number of nuclei per fiber, and myonuclear density. Results. There was a statistical difference (p < 0.05) between injured and non-injured GTN muscles in terms of myonuclei per fiber. There were no statistical differences (p < 0.01) between the 4 treatment groups for any of the outcome measures chosen as biomarkers of skeletal muscle regeneration. Conclusions. The specific hypothesis was not supported. There is no evidence that the specific continuous ultrasound and exercise protocols investigated interact to enhance skeletal muscle regeneration following contusion injury.

ISBN: 9780496887514Subjects--Topical Terms:

1017835
Biology, Animal Physiology.

Ultrasound and exercise in skeletal muscle regeneration.
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