| 紀錄類型: |
書目-語言資料,印刷品
: Monograph/item
|
| 正題名/作者: |
Osteoporosis/ edited by Robert Marcus ... [et al.]. |
| 其他作者: |
Marcus, Robert, |
| 出版者: |
Amsterdam ;Elsevier Academic Press, : c2008., |
| 面頁冊數: |
2 v. (xxv, 1941 p., [16] p. of plates) :ill. ;29 cm. |
| 內容註: |
Introduction -- The Bone Organ System: Form and Function -- The Nature of Osteoporosis -- The Economics of Osteoporosis -- Reflections on Osteoporosis -- Skeletal Heterogeneity and the Purposes of Bone Remodeling: Implications for the -- Understanding of Osteoporosis -- Basic Science/Bone Biology -- Osteoblast Biology -- Osteoclast Biology -- Osteocytes -- The Regulatory Role of Matrix Proteins in Mineralization of Bone -- Development of the Skeleton -- Mouse Genetics as a Tool to Study Bone Development and Physiology -- Parathyroid Hormone and Parathyroid Hormone-Related Protein -- Vitamin D: Biology, Action, and Clinical Implications -- Regulation of Bone Cell Function by Estrogens -- Androgens and Skeletal Biology: Basic Mechanisms -- Phosphatonins -- Wnt Signaling in Bone -- Cytokines and Bone Remodeling -- Skeletal Growth Factors -- Intercellular Communication During Bone Remodeling -- Structural and Biomechanics -- Skeletal Development: Mechanical Consequences of Growth, Aging and Disease -- Inhibition of Osteoporosis by Biophysical Intervention -- Biomechanics of Age-Related Fractures -- Bone Quality -- Epidemiology & Risk Factors -- Epidemiologic Methods in Studies of Osteoporosis -- Race, Ethnicity and Osteoporosis -- The Study of Osteoporotic Fractures (SOF): Major Findings and Contributions -- Bone Mineral Acquisition in Utero and During Infancy and Childhood -- Bone Acquisition in Adolescence -- Genetic Determinants of Osteoporosis -- Nutrition and Risk for Osteoporosis -- Physical Activity in Prevention of Osteoporosis and Associated Fractures -- Premenopausal Reproductive and Hormonal Characteristics and the Risk for Osteoporosis -- Non-Skeletal Risk Factors for Osteoporosis and Fractures -- Falls as Risk Factors for Fracture -- Assessment of Fracture Risk -- Outcomes of Osteoporotic Fractures -- Pathophysiology -- Local and Systemic Factors in the Pathogenesis of Osteoporosis -- Animal Models for Osteoporosis -- Estrogen, Bone Homeostasis and Osteoporosis -- Postmenopausal Osteoporosis: How the Hormonal Changes of Menopause Cause Bone Loss -- Osteoporosis in Men: Epidemiology, Pathophysiology, and Clinical Characterization -- Osteoporosis in Childhood and Adolescence -- Glucocorticoid-Induced Osteoporosis -- Adult Scoliosis, Degenerative Disease, and BMD: a Sub-Segmental Analytic Approach -- Mechanisms of Immobilization-induced Bone Loss -- Leptin-Dependent Regulation of Bone Mass -- Thyroid Hormone and the Skeleton -- Osteoporosis in Gastrointestinal, Pancreatic, and Hepatic Disease -- The Skeletal Actions of Parathyroid Hormone in Primary Hyperparathyroidism and in Osteoporosis -- Osteogenesis Imperfecta and Other Defects of Bone Development as Occasional Causes of Adult Osteoporosis -- Osteoporosis Associated with Illnesses and Medications -- Transplantation Osteoporosis -- Osteoporosis Associated with Cancer Therapy -- Osteoporosis Associated with Pregnancy -- Osteoporosis Associated with Rheumatologic Disease -- Oral Bone Loss and Systemic Osteopenia: Potential Treatment and Risks -- Localized Osteoporosis -- Evaluation and Management -- Evaluation of the Patient with Osteoporosis or at Risk for Osteoporosis -- Who Should be Screened: Who Should be Treated? -- Radiology of Osteoporosis -- Clinical Use of Bone Densitometry -- Biochemical Markers of Bone Turnover in Osteoporosis -- The Conundrum of Compliance and Persistence with Oral Bisphosphonates for Postmenopausal Osteoporosis -- An Orthopedic Perspective of Osteoporosis -- Lessons from Bone Histomorphometry on the Mechanism of Action of Osteoporosis Drugs -- Pharmacology and Therapeutics -- Design Considerations for Clinical Investigations of Osteoporosis -- Regulatory Considerations for the Design and Conduct of Osteoporosis Registration Trials -- Evidence-Based Osteoporosis Care -- The Role of Calcium in the Treatment of Osteoporosis -- Vitamin D and its Metabolites and Analogs in the Management of Osteoporosis -- Estrogen Therapy: Prevention and Treatment of Osteoporosis -- Estrogen Analogues: Selective Estrogen Receptor Modulators (SERMs) and Phytoestrogens -- Bisphosphonates: Pharmacology and Use in the Treatment of Osteoporosis -- Calcitonin in Osteoporosis -- Strontium Therapy for Osteoporosis -- Androgens -- Treatment with PTH Peptides -- Growth Hormone and Insulin-like Growth Factors: Potential Applications and Limitations in the Management of Osteoporosis -- New approaches to Osteoporosis Therapeutics. |
| 內容註: |
The bone organ system: form and function -- The nature of osteporosis -- The economics of osteoporosis -- Reflections on osteoporosis -- Skeletal heterogeneity and the purposes of bone remodeling: implications for the understanding of osteporosis -- Osteoblast biology -- Osteoclast biology -- Osteocytes -- The regulatory role of matrix proteins in mineralization of bone -- Development of the skeleton -- Mouse genetics as a tool to study bone development and physiology -- Parathyroid hormone and parathyroid hormone-related protein -- Vitamin D: biology, action, and clinical implications -- Regulation of bone cell function by estrogens -- Androgens and skeletal biology: basic mechanisms -- Phosphatonins -- Wnt Signaling in bone -- Cytokins and bone remodeling -- Skeletal growth factors -- Intercellular communication during bone remodeling -- Skeletal development: mechanical consequences of growth, aging, and disease -- Inhibition of osteoporosis by biophysical intervention -- Biomechanics of age-related fractures -- Bone quality -- Epidemiologic methods in studies of osteoporosis -- Race, ethnicity and osteoporosis -- The study of osteoporotic fractures: major findings and contributions -- Bone mineral acquistion In Utero and during infancy and childhood -- Bone acquisition in adolescence -- Genetic determinants of osteoporosis -- Nutrition and risk for osteoporosis -- Physical activity in prevention of osteoporosis and associated fractures -- Premenopausal reproductive and hormonal characteristics and the risk for osteoporosis -- Nonskeletal risk factors for osteoporosis and fractures -- Falls as risk factors for fracture -- Assessment of fracture risk -- Outcomes of osteoporotic fractures -- Local and systemic factors in the pathogenesis of osteoporosis -- Animal modesl for osteoporosis -- Estrogen, bone homeostasis, and osteoporosis -- Postmenopausal osteoporosis: how the hormonal changes of menopause cause bone loss -- Osteoporosis in men: epidemiology, pathophysiology, and clinical characterization -- Osteoporosis in childhood and adolescence -- |
| 內容註: |
Glucocorticoid-induced osteoporosis -- Adult scoliosis, degenerative disease, and BMD: a subsegmental analytic approach -- Mechanisms of immobilization-induced bone loss -- Leptin-dependent regulation of bone mass -- Thyroid hormone and the skeleton -- Osteoporosis in gastrointestinal, pancreatic, and hepatic diseases -- The skeletal actions of parathyroid hormone in primary hyperparathyroidism and in osteoporosis -- Osteogenesis imperfecta and other defects of bone development as occasional causes of adult osteoporosis -- Osteoporosis associated with illnesses and medications -- Transplantation osteoporosis -- Osteoporosis associated with cancer therapy -- Osteoporosis associated with pregnancy -- Osteoporosis associated with rheumatologic disorders -- Oral bone loss and systemic osteopenia: potential treatment and risks -- Localized osteoporosis -- Evaluation of the patient with osteoporosis or at risk for osteoporosis -- Who should be screened: who should be treated? -- Radiology of osteoporosis -- Clinical use of bone densitometry -- Biochemical markers of bone turnover in osteoporosis -- The conundrum of compliance and persistence with oral biophosphonates for postmenopausal osteoporosis -- An orthopedic perspective of osteoporosis -- Lessons from the bone histomorphometry on the mechanism of action of osteoporosis drugs -- Design considerations for clinical investigations of osteoporosis -- Regulatory considerations for the design and conduct of osteoporosis registration trials -- Evidence-based osteoporosis care -- The role of calcium in the treatment of osteoporosis -- Vitamin D and its metabolites and analogs in the management of osteoporosis -- Estrogen therapy: prevention and treatment of osteoporosis -- Estrogen analogues: selective estrogen receptor modulators and phytoestrogens -- Bisphosphonates: pharmacology and use in the treatment of osteoporosis -- Calcitonin in osteoporosis -- Strontium ranelate -- Androgens -- Treatment with PTH peptides -- Growth hormone and insulin-like growth factors: potential applications and limitations in the management of osteoporosis -- New approaches to osteoporosis therapeutics. |
| 標題: |
Osteoporosis. - |
| 電子資源: |
http://www.sciencedirect.com/science/book/9780123705440An electronic book accessible through the World Wide Web; click for information |
| ISBN: |
0123705444 |