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Salivary cortisol and depression ris...

State University of New York at Stony Brook.

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Salivary cortisol and depression risk: Relations with child temperament, maternal history of depression, parenting, and life stress.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
正題名/作者:	Salivary cortisol and depression risk: Relations with child temperament, maternal history of depression, parenting, and life stress./
作者:	Dougherty, Lea Rose.
面頁冊數:	122 p.
附註:	Source: Dissertation Abstracts International, Volume: 69-12, Section: B, page: 7807.
Contained By:	Dissertation Abstracts International69-12B.
標題:	Psychology, Clinical. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoeng/servlet/advanced?query=3340098
ISBN:	9780549942894

Salivary cortisol and depression risk: Relations with child temperament, maternal history of depression, parenting, and life stress.
Dougherty, Lea Rose.

Salivary cortisol and depression risk: Relations with child temperament, maternal history of depression, parenting, and life stress. - 122 p.

Source: Dissertation Abstracts International, Volume: 69-12, Section: B, page: 7807.

Thesis (Ph.D.)--State University of New York at Stony Brook, 2008.

Dysregulation of the HPA system has been consistently associated with the affective disorders. The current study aims to test the hypothesis that low positive emotionality (PE), a possible temperamental precursor to depression, is associated with HPA axis functioning in children prior to the onset of a depressive disorder. This study also aims to examine the unique and joint effects of some of the complex factors related to children's early HPA axis functioning and depression risk, including maternal history of depression, parenting and life stress, alongside early temperament. These factors were examined in relation to children's salivary cortisol levels in response to a laboratory stressor and to children's home basal cortisol levels. One hundred and sixty-six preschool-aged children and their biological parents were recruited from a larger study examining temperamental risk for mood disorders: 166 children completed all 4 salivary cortisol samples during the lab visit; 94 children provided a home morning salivary cortisol sample; and 93 children provided an evening salivary cortisol sample. Child temperament and parenting were assessed using laboratory observational measures, and maternal depression and child life stressors were assessed with semi-structured clinical interviews. First, mixed effects modeling was used to examine predictors of children's laboratory cortisol reactivity. We found that temperamental negative emotionality (NE), behavioral inhibition (BI), parental hostility and life stress were significantly associated with components of the trajectory of cortisol during the lab visit. Furthermore, several significant interactions emerged that predicted greater laboratory cortisol reactivity, including child low PE X maternal melancholic depression, child BI X maternal melancholic depression, child low PE X parental hostility, and maternal depression X parental hostility. In addition, child BI interacted with parental support to predict lower laboratory baseline cortisol levels. Next, multiple regression was used to examine predictors of children's home basal cortisol levels. We found that both child low PE and maternal melancholic depression were significantly associated with higher morning cortisol levels, suggesting potential depressive endophenotypes. The study's findings are summarized in terms of risk, resilience, and potentiation as they relate to the development of neuroendocrine dysfunction in young children, and suggest several potential avenues for future research.

ISBN: 9780549942894Subjects--Topical Terms:

524864
Psychology, Clinical.

Salivary cortisol and depression risk: Relations with child temperament, maternal history of depression, parenting, and life stress.
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