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Mammographic density and different b...
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University of Southern California., Preventive Medicine (Health Behavior Research).
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Mammographic density and different breast cancer subtypes defined by prognostic biomarkers.
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
正題名/作者:
Mammographic density and different breast cancer subtypes defined by prognostic biomarkers./
作者:
Luo, Jianning.
面頁冊數:
31 p.
附註:
Adviser: Giske Ursin.
Contained By:
Masters Abstracts International46-06.
標題:
Biology, Biostatistics. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1454081
ISBN:
9780549608486
Mammographic density and different breast cancer subtypes defined by prognostic biomarkers.
Luo, Jianning.
Mammographic density and different breast cancer subtypes defined by prognostic biomarkers.
- 31 p.
Adviser: Giske Ursin.
Thesis (M.S.)--University of Southern California, 2008.
Mammographic density is a strong risk factor for breast cancer. However, it has been unclear whether it is a risk factor for all the subtypes of breast cancer defined by prognostic biomarkers.
ISBN: 9780549608486Subjects--Topical Terms:
1018416
Biology, Biostatistics.
Mammographic density and different breast cancer subtypes defined by prognostic biomarkers.
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Source: Masters Abstracts International, Volume: 46-06, page: 3132.
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Thesis (M.S.)--University of Southern California, 2008.
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Mammographic density is a strong risk factor for breast cancer. However, it has been unclear whether it is a risk factor for all the subtypes of breast cancer defined by prognostic biomarkers.
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Our results suggest that mammographic density is a risk factor for both basal-like and luminal A breast cancer.
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We examined the association of mammographic density with subtypes of breast cancer (defined using immunohistochemical analysis of breast tumors) among 479 female breast cancer patients and 376 controls aged 35-64 years in Los Angeles County using multivariable unconditional logistic regression models. The subtypes we focused on include basal-like (defined as ER-, PR-, HER2-) and luminal A (defined as ER+ and/or PR+, HER2-).
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Mammographic density was positively associated with both basal-like and luminal A breast cancers among postmenopausal women (both ptrend ≤ 0.03). Women having 60 and more percent mammographic density had approximately 2-3 times higher risk for these two subtypes compared to those with less than 10 percent of mammographic density.
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