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Localization and semi-quantitation o...

State University of New York at Buffalo.

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Localization and semi-quantitation of NMDA2A and NMDA2B receptor mRNAs in auditory cortex.

Record Type:	Language materials, printed : Monograph/item
Title/Author:	Localization and semi-quantitation of NMDA2A and NMDA2B receptor mRNAs in auditory cortex./
Author:	Liu, Jiayun.
Description:	82 p.
Notes:	Source: Masters Abstracts International, Volume: 45-02, page: 0740.
Contained By:	Masters Abstracts International45-02.
Subject:	Biology, Molecular. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1440063

Localization and semi-quantitation of NMDA2A and NMDA2B receptor mRNAs in auditory cortex.
Liu, Jiayun.

Localization and semi-quantitation of NMDA2A and NMDA2B receptor mRNAs in auditory cortex. - 82 p.

Source: Masters Abstracts International, Volume: 45-02, page: 0740.

Thesis (M.S.)--State University of New York at Buffalo, 2007.

NMDA (N-methyl-d-aspartate) receptors are essential for learning and formation of memory. Recent research reported that expression of NMDA2A and NMDA2B receptor mRNAs in the cortices of adult rats decreased after intensive auditory learning. To confirm and better understand the phenomenon, radioactive in situ hybridization (ISH) was applied to locate and quantitate the expressed NMDA2A and NMDA2B receptor mRNAs in sections of auditory cortices prepared from one control and one auditory trained rat.Subjects--Topical Terms:

1017719
Biology, Molecular.

Localization and semi-quantitation of NMDA2A and NMDA2B receptor mRNAs in auditory cortex.
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005 20100629
008 100629s2007 ||||||||||||||||| ||eng d
035 $a (UMI)AAI1440063
035 $a AAI1440063
040 $a UMI $c UMI
100 1 $a Liu, Jiayun. $3 1017818
245 1 0 $a Localization and semi-quantitation of NMDA2A and NMDA2B receptor mRNAs in auditory cortex.
300 $a 82 p.
500 $a Source: Masters Abstracts International, Volume: 45-02, page: 0740.
502 $a Thesis (M.S.)--State University of New York at Buffalo, 2007.
520 $a NMDA (N-methyl-d-aspartate) receptors are essential for learning and formation of memory. Recent research reported that expression of NMDA2A and NMDA2B receptor mRNAs in the cortices of adult rats decreased after intensive auditory learning. To confirm and better understand the phenomenon, radioactive in situ hybridization (ISH) was applied to locate and quantitate the expressed NMDA2A and NMDA2B receptor mRNAs in sections of auditory cortices prepared from one control and one auditory trained rat.
520 $a Cells expressing both NMDA2A and NMDA2B receptor subunit mRNAs were found in the pyramidal layer of auditory cortices, while expression level differences of NMDA2A and NMDA2B receptor subunit mRNAs in auditory cortices between control and trained rats were not detected. This pilot study has confirmed the feasibility of the ISH protocol we developed, though some further refinement will need to be done to distinguish subtle expression pattern of the NMDA receptor mRNAs that are associated with learning in the auditory cortex.
590 $a School code: 0656.
650 4 $a Biology, Molecular. $3 1017719
650 4 $a Biology, Neuroscience. $3 1017680
650 4 $a Biology, Physiology. $3 1017816
690 $a 0307
690 $a 0317
690 $a 0719
710 2 $a State University of New York at Buffalo. $3 1017814
773 0 $t Masters Abstracts International $g 45-02.
790 $a 0656
791 $a M.S.
792 $a 2007
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1440063