東華大學圖書館 |

Transcription factors in blood cell development

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Transcription factors in blood cell development/ edited by Tilman Borggrefe, Benedetto Daniele Giaimo.
其他作者:	Borggrefe, Tilman.
出版者:	Cham :Springer Nature Switzerland : : 2024.,
面頁冊數:	xliv, 430 p. :ill. (chiefly col.), digital ;24 cm.
內容註:	Part 1 - Stem/Progenitor Cells -- Chapter 1. MYB - A Key Transcription Factor in the Hematopoietic System Subject to many Levels of Control - Roza Berhanu Lemma, Bettina Maria Fuglerud, Jon Frampton & Odd Stokke Gabrielsen -- Part 2 - T-Cells -- Chapter 2. Ikaros Family Transcription Factors in Lymphocyte Differentiation and Function - Philippe Kastner & Susan Chan -- Chapter 3. The Role of the Transcriptional Co-Activator BOB.1/OBF.1 in Adaptive Immunity - Annika C. Betzler & Cornelia Brunner -- Chapter 4. Key Functions of the Transcription Factor BCL6 during T-Cell Differentiation - Chara Konstantakopoulou & Mihalis Verykokakis -- Part 3 - B-Cells -- Chapter 5. The Function of E2A in B-Cell Development - Masaki Miyazaki & Kazuko Miyazaki -- Chapter 6. Hypoxia and the Hypoxia-Inducible Factors in Lymphocyte Differentiation and Function - Mark Boothby & Sung Hoon Cho -- Chapter 7. Early B-Cell Factor 1: An Archetype for a Lineage-Restricted Transcription Factor Linking Development to Disease - Mikael Sigvardsson -- Part 4 - Myeloid Cells -- Chapter 8. Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function - Marc Pfefferlé & Florence Vallelian -- Part 5 - Erythroid Cells -- Chapter 9. Trancriptional Repressor BCL11A In Erythroid Cells - Ge Zheng & Stuart H. Orkin -- Chapter 10. Erythroid Krüppel-like Factor / KLF1: a Surprisingly Versatile Regulator of Erythroid Differentiation - James J Bieker & Sjaak Philipsen -- Chapter 11. Transcription Factor TAL1 in Erythropoiesis - Johannes Fechner & Jörn Lausen -- Part 6 - Megakaryocytes -- Chapter 12. GATA1 in Normal and Pathologic Megakaryopoiesis and Platelet Development - Kaoru Takasaki & Stella T. Chou -- Part 7 - Leukemia/Lymphoma -- Chapter 13. The Diverse Roles of ETV6 Alterations in B-Lymphoblastic Leukemia and other Hematopoietic Cancers - Alexander C. Monovich, Aishwarya Gurumurthy & Russell J.H. Ryan -- Chapter 14. Function of PML-RARA in Acute Promyelocytic Leukemia - Ugo Testa & Elvira Pelosi -- Cha[ter 15. MYB as a Critical Transcription Factor and Potential Therapeutic Target in AML - Mary Louise Clarke, Odd Stokke Gabrielsen & Jon Frampton -- Chapter 16. ETS1 Function in Leukemia and Lymphoma - Rebecca A. Luchtel -- Chapter 17. The Molecular and Biological Function of MEF2D in Leukemia - Pengcheng Zhang & Rui Lu -- Chapter 18. HOXA9 Regulome and Pharmacological Interventions in Leukemia - Sajesan Aryal & Rui Lu.
Contained By:	Springer Nature eBook
標題:	Transcription factors. -
電子資源:	https://doi.org/10.1007/978-3-031-62731-6
ISBN:	9783031627316

Transcription factors in blood cell development
Transcription factors in blood cell development[electronic resource] /edited by Tilman Borggrefe, Benedetto Daniele Giaimo. - Cham :Springer Nature Switzerland :2024. - xliv, 430 p. :ill. (chiefly col.), digital ;24 cm. - Advances in experimental medicine and biology,v. 14592214-8019 ;. - Advances in experimental medicine and biology ;v. 1459..

Part 1 - Stem/Progenitor Cells -- Chapter 1. MYB - A Key Transcription Factor in the Hematopoietic System Subject to many Levels of Control - Roza Berhanu Lemma, Bettina Maria Fuglerud, Jon Frampton & Odd Stokke Gabrielsen -- Part 2 - T-Cells -- Chapter 2. Ikaros Family Transcription Factors in Lymphocyte Differentiation and Function - Philippe Kastner & Susan Chan -- Chapter 3. The Role of the Transcriptional Co-Activator BOB.1/OBF.1 in Adaptive Immunity - Annika C. Betzler & Cornelia Brunner -- Chapter 4. Key Functions of the Transcription Factor BCL6 during T-Cell Differentiation - Chara Konstantakopoulou & Mihalis Verykokakis -- Part 3 - B-Cells -- Chapter 5. The Function of E2A in B-Cell Development - Masaki Miyazaki & Kazuko Miyazaki -- Chapter 6. Hypoxia and the Hypoxia-Inducible Factors in Lymphocyte Differentiation and Function - Mark Boothby & Sung Hoon Cho -- Chapter 7. Early B-Cell Factor 1: An Archetype for a Lineage-Restricted Transcription Factor Linking Development to Disease - Mikael Sigvardsson -- Part 4 - Myeloid Cells -- Chapter 8. Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function - Marc Pfefferlé & Florence Vallelian -- Part 5 - Erythroid Cells -- Chapter 9. Trancriptional Repressor BCL11A In Erythroid Cells - Ge Zheng & Stuart H. Orkin -- Chapter 10. Erythroid Krüppel-like Factor / KLF1: a Surprisingly Versatile Regulator of Erythroid Differentiation - James J Bieker & Sjaak Philipsen -- Chapter 11. Transcription Factor TAL1 in Erythropoiesis - Johannes Fechner & Jörn Lausen -- Part 6 - Megakaryocytes -- Chapter 12. GATA1 in Normal and Pathologic Megakaryopoiesis and Platelet Development - Kaoru Takasaki & Stella T. Chou -- Part 7 - Leukemia/Lymphoma -- Chapter 13. The Diverse Roles of ETV6 Alterations in B-Lymphoblastic Leukemia and other Hematopoietic Cancers - Alexander C. Monovich, Aishwarya Gurumurthy & Russell J.H. Ryan -- Chapter 14. Function of PML-RARA in Acute Promyelocytic Leukemia - Ugo Testa & Elvira Pelosi -- Cha[ter 15. MYB as a Critical Transcription Factor and Potential Therapeutic Target in AML - Mary Louise Clarke, Odd Stokke Gabrielsen & Jon Frampton -- Chapter 16. ETS1 Function in Leukemia and Lymphoma - Rebecca A. Luchtel -- Chapter 17. The Molecular and Biological Function of MEF2D in Leukemia - Pengcheng Zhang & Rui Lu -- Chapter 18. HOXA9 Regulome and Pharmacological Interventions in Leukemia - Sajesan Aryal & Rui Lu.

This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that contain a part of a transcription factor. In the given chapters covering each one particular example, the function of transcription factors is characterized in normal as well as leukemic contexts. New technologies such as ChIP-Seq or RNA-Seq, that make use of genome-wide sequencing, have shown that such master regulators of blood cell development often work in combinatorial fashion and, when dysregulated, results in leukemogenesis. This book is not only intended for experts but it should also be a useful resource for younger scientists or scientists from other disciplines, who may use this book as a stimulating starting point for further discoveries and/ or translational endeavors.

ISBN: 9783031627316

Standard No.: 10.1007/978-3-031-62731-6doiSubjects--Topical Terms:

669191
Transcription factors.

LC Class. No.: QP552.T68

Dewey Class. No.: 572.8845

Transcription factors in blood cell development
LDR:04539nmm a2200337 a 4500 001 2373731
003 DE-He213
005 20240717125227.0
006 m d
007 cr nn 008maaau
008 241231s2024 sz s 0 eng d
020 $a 9783031627316 $q (electronic bk.)
020 $a 9783031627309 $q (paper)
024 7 $a 10.1007/978-3-031-62731-6 $2 doi
035 $a 978-3-031-62731-6
040 $a GP $c GP
041 0 $a eng
050 4 $a QP552.T68
072 7 $a PSD $2 bicssc
072 7 $a SCI029000 $2 bisacsh
072 7 $a PSD $2 thema
082 0 4 $a 572.8845 $2 23
090 $a QP552.T68 $b T772 2024
245 0 0 $a Transcription factors in blood cell development $h [electronic resource] / $c edited by Tilman Borggrefe, Benedetto Daniele Giaimo.
260 $a Cham : $b Springer Nature Switzerland : $b Imprint: Springer, $c 2024.
300 $a xliv, 430 p. : $b ill. (chiefly col.), digital ; $c 24 cm.
490 1 $a Advances in experimental medicine and biology, $x 2214-8019 ; $v v. 1459
505 0 $a Part 1 - Stem/Progenitor Cells -- Chapter 1. MYB - A Key Transcription Factor in the Hematopoietic System Subject to many Levels of Control - Roza Berhanu Lemma, Bettina Maria Fuglerud, Jon Frampton & Odd Stokke Gabrielsen -- Part 2 - T-Cells -- Chapter 2. Ikaros Family Transcription Factors in Lymphocyte Differentiation and Function - Philippe Kastner & Susan Chan -- Chapter 3. The Role of the Transcriptional Co-Activator BOB.1/OBF.1 in Adaptive Immunity - Annika C. Betzler & Cornelia Brunner -- Chapter 4. Key Functions of the Transcription Factor BCL6 during T-Cell Differentiation - Chara Konstantakopoulou & Mihalis Verykokakis -- Part 3 - B-Cells -- Chapter 5. The Function of E2A in B-Cell Development - Masaki Miyazaki & Kazuko Miyazaki -- Chapter 6. Hypoxia and the Hypoxia-Inducible Factors in Lymphocyte Differentiation and Function - Mark Boothby & Sung Hoon Cho -- Chapter 7. Early B-Cell Factor 1: An Archetype for a Lineage-Restricted Transcription Factor Linking Development to Disease - Mikael Sigvardsson -- Part 4 - Myeloid Cells -- Chapter 8. Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function - Marc Pfefferlé & Florence Vallelian -- Part 5 - Erythroid Cells -- Chapter 9. Trancriptional Repressor BCL11A In Erythroid Cells - Ge Zheng & Stuart H. Orkin -- Chapter 10. Erythroid Krüppel-like Factor / KLF1: a Surprisingly Versatile Regulator of Erythroid Differentiation - James J Bieker & Sjaak Philipsen -- Chapter 11. Transcription Factor TAL1 in Erythropoiesis - Johannes Fechner & Jörn Lausen -- Part 6 - Megakaryocytes -- Chapter 12. GATA1 in Normal and Pathologic Megakaryopoiesis and Platelet Development - Kaoru Takasaki & Stella T. Chou -- Part 7 - Leukemia/Lymphoma -- Chapter 13. The Diverse Roles of ETV6 Alterations in B-Lymphoblastic Leukemia and other Hematopoietic Cancers - Alexander C. Monovich, Aishwarya Gurumurthy & Russell J.H. Ryan -- Chapter 14. Function of PML-RARA in Acute Promyelocytic Leukemia - Ugo Testa & Elvira Pelosi -- Cha[ter 15. MYB as a Critical Transcription Factor and Potential Therapeutic Target in AML - Mary Louise Clarke, Odd Stokke Gabrielsen & Jon Frampton -- Chapter 16. ETS1 Function in Leukemia and Lymphoma - Rebecca A. Luchtel -- Chapter 17. The Molecular and Biological Function of MEF2D in Leukemia - Pengcheng Zhang & Rui Lu -- Chapter 18. HOXA9 Regulome and Pharmacological Interventions in Leukemia - Sajesan Aryal & Rui Lu.
520 $a This book describes transcription factors in the context of hematopoietic development and reveal mechanistic insights how they orchestrate specific gene expression patterns. Several examples from lymphoid and myeloid lineages are given as well as particular examples of leukemia fusion proteins that contain a part of a transcription factor. In the given chapters covering each one particular example, the function of transcription factors is characterized in normal as well as leukemic contexts. New technologies such as ChIP-Seq or RNA-Seq, that make use of genome-wide sequencing, have shown that such master regulators of blood cell development often work in combinatorial fashion and, when dysregulated, results in leukemogenesis. This book is not only intended for experts but it should also be a useful resource for younger scientists or scientists from other disciplines, who may use this book as a stimulating starting point for further discoveries and/ or translational endeavors.
650 0 $a Transcription factors. $3 669191
650 0 $a Blood cells. $3 865835
650 1 4 $a Gene Transcription. $3 3594188
650 2 4 $a Cell Biology. $3 892383
650 2 4 $a Post-translational Modifications. $3 3603792
650 2 4 $a Haematopoietic System. $3 3663925
650 2 4 $a Developmental Biology and Stem Cells. $3 3531341
700 1 $a Borggrefe, Tilman. $3 3337963
700 1 $a Giaimo, Benedetto Daniele. $3 3337964
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
830 0 $a Advances in experimental medicine and biology ; $v v. 1459. $3 3722092
856 4 0 $u https://doi.org/10.1007/978-3-031-62731-6
950 $a Biomedical and Life Sciences (SpringerNature-11642)