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Part-1: General Considerations. History of traumatic brain injury and the evolution of neuromonitoring: an overview -- The importance of pathways: Trauma Center and Neurocritical care unit -- The central role of specialized Neurocritical Care Team: Standards of Neurologic Critical Care Units -- The central role of specialized Neurocritical Care Team: nursing perspective in neurocritical care practice -- Part-2: Diagnosis and neuromonitoring. Clinical evaluation: neurological examination and standardized scales -- Neuroradiological imaging -- Interactions between volumes, flows and pressures in the brain: intracranial pressure, cerebral perfusion pressure, cerebral autoregulation and the concept of compensatory reserve -- Non-invasive neuromonitoring: Near infrared spectroscopy and Pupillometry -- Non-invasive neuromonitoring: Neurosonology - TCD, TCCD and optic nerve ultrasound -- Neurophysiology: EEG and Evoked potentials -- Brain oxygen measurements and cerebral metabolism: Brain tissue oxygenation (PbtO2), Jugular bulb oximetry, intracerebral microdialysis, and the role of brain injury biomarkers -- Future direction: Multimodality monitoring and machine learning -- Out of hospital management of trauma brain injury -- Sedation, pain and delirium management -- Intracranial pressure management: The stepwise approach -- Ventilation strategy and the timing of tracheotomy: a different approach in trauma? -- Systemic hemodynamics monitoring & Blood pressure target during acute brain injury -- Temperature control and the role of therapeutic hypothermia -- Coagulation, transfusion, reversal of anticoagulant and antiplatelet agents, and thromboembolism prophylaxis in acute brain injury: point of care test and treatment -- Fluid management and Hyperosmolar therapy in neurotrauma -- Neurosurgical treatment and the role of Decompressive craniotomy -- Multiple trauma management: treatment of abdominal injury in combination with trauma brain injury -- Polycompartment syndrome in severe trauma braininjury -- Seizure: prophylaxis and treatment in acute brain injury -- Endocrine consequence of traumatic brain injury -- Infection management in neurocritical care setting -- Trauma brain injury in pregnant patients -- Trauma brain injury in pediatric patients -- Trauma brain injury in elderly patients -- Part- 4: Final Considerations. Prognostication and treatment-limiting decisions after severe traumatic brain injury -- Clinical and bioethical perspective on brain death, organ donation, and family communication -- Long-term outcome and the role of Neurorehabilitation after severe Traumatic brain injury. |