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Values-Driven Decision Support for Cadaveric Kidney Transplant Decisions.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Values-Driven Decision Support for Cadaveric Kidney Transplant Decisions./
作者:
Diao, Tianhui.
面頁冊數:
1 online resource (66 pages)
附註:
Source: Dissertations Abstracts International, Volume: 84-05, Section: A.
Contained By:
Dissertations Abstracts International84-05A.
標題:
Hemodialysis. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=29755916click for full text (PQDT)
ISBN:
9798357508379
Values-Driven Decision Support for Cadaveric Kidney Transplant Decisions.
Diao, Tianhui.
Values-Driven Decision Support for Cadaveric Kidney Transplant Decisions.
- 1 online resource (66 pages)
Source: Dissertations Abstracts International, Volume: 84-05, Section: A.
Thesis (Ph.D.)--Stanford University, 2022.
Includes bibliographical references
Although the demand for kidney transplants continues to greatly exceed supply, most cadaveric kidneys are o↵ered to multiple patients before being accepted or discarded. The decision of whether to accept or decline an o↵ered kidney is dicult because of uncertainty about the quality and length of the patient's remaining life. If they decline the o↵er, then it is uncertain whether they will ever receive a kidney, let alone one of higher quality than the one currently available.This thesis develops a decision-analytical approach to model the situation facing patients waiting for kidney transplants, based on twenty years of data on patients waiting for transplants in the US. When they are o↵ered a matching kidney, they and their surgeons must decide whether to accept the o↵er. We model each patient's situation as a one-step decision-making problem that compares the observed remaining lifetime or landmark survival for similar patients who accepted an o↵ered kidney of similar quality and those who declined such an o↵er. This information can facilitate a meaningful conversation between a patient and their surgeon that can address the particular preferences and circumstances of that patient.Our analysis shows that for patients in almost every situation, the observed remaining lifetime for similar patients was longer if they accepted the o↵er than if they declined it, and sometimes significantly longer. Because accepting an o↵er almost always reduces the time a patient will spend on dialysis, it also improves the quality of life for most patients. Therefore, we believe that our results should encourage patients to accept many more o↵ered kidneys than they have in the past.
Electronic reproduction.
Ann Arbor, Mich. :
ProQuest,
2023
Mode of access: World Wide Web
ISBN: 9798357508379Subjects--Topical Terms:
802778
Hemodialysis.
Index Terms--Genre/Form:
542853
Electronic books.
Values-Driven Decision Support for Cadaveric Kidney Transplant Decisions.
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Source: Dissertations Abstracts International, Volume: 84-05, Section: A.
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Although the demand for kidney transplants continues to greatly exceed supply, most cadaveric kidneys are o↵ered to multiple patients before being accepted or discarded. The decision of whether to accept or decline an o↵ered kidney is dicult because of uncertainty about the quality and length of the patient's remaining life. If they decline the o↵er, then it is uncertain whether they will ever receive a kidney, let alone one of higher quality than the one currently available.This thesis develops a decision-analytical approach to model the situation facing patients waiting for kidney transplants, based on twenty years of data on patients waiting for transplants in the US. When they are o↵ered a matching kidney, they and their surgeons must decide whether to accept the o↵er. We model each patient's situation as a one-step decision-making problem that compares the observed remaining lifetime or landmark survival for similar patients who accepted an o↵ered kidney of similar quality and those who declined such an o↵er. This information can facilitate a meaningful conversation between a patient and their surgeon that can address the particular preferences and circumstances of that patient.Our analysis shows that for patients in almost every situation, the observed remaining lifetime for similar patients was longer if they accepted the o↵er than if they declined it, and sometimes significantly longer. Because accepting an o↵er almost always reduces the time a patient will spend on dialysis, it also improves the quality of life for most patients. Therefore, we believe that our results should encourage patients to accept many more o↵ered kidneys than they have in the past.
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