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Stress, Inflammation, and Mood: A Role for Leptin?
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Stress, Inflammation, and Mood: A Role for Leptin?/
作者:
Hodgin, Kathleen.
出版者:
Ann Arbor : ProQuest Dissertations & Theses, : 2021,
面頁冊數:
85 p.
附註:
Source: Masters Abstracts International, Volume: 83-01.
Contained By:
Masters Abstracts International83-01.
標題:
Psychology. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28491226
ISBN:
9798516074936
Stress, Inflammation, and Mood: A Role for Leptin?
Hodgin, Kathleen.
Stress, Inflammation, and Mood: A Role for Leptin?
- Ann Arbor : ProQuest Dissertations & Theses, 2021 - 85 p.
Source: Masters Abstracts International, Volume: 83-01.
Thesis (M.A.)--The University of Alabama at Birmingham, 2021.
This item must not be sold to any third party vendors.
Prior research has suggested a possible role for the proinflammatory adipokine leptin in depression. Leptin has also been associated with stress, a known predictor of depression. The purpose of this project was to investigate associations between stress, leptin, and depressed mood. We used data from a larger observational study that collected daily levels of plasma leptin and self-reported stress and depressed mood from 55 women over 25 days. Women with and without chronic fatigue syndrome (CFS) were included. We hypothesized the following: increased stress would be associated with both worsened mood and higher leptin, and that leptin would be positively associated with depressed mood. Vitamin D was also explored as a potential moderating factor. Linear mixed models were used to analyze associations between daily stress, leptin, and mood at a 1-day time lag. Results suggested an association between stress and next-day leptin, dependent on vitamin D level (p = .018). Leptin also varied by patient group depending on vitamin D (p = .018), with highest leptin observed among women with CFS and lower vitamin D (< 20 ng/mL). Overall, findings support further investigation of vitamin D in relation to stress and leptin; leptin, however, does not appear to play a substantial role in depressed mood.
ISBN: 9798516074936Subjects--Topical Terms:
519075
Psychology.
Subjects--Index Terms:
Chronic Fatigue Syndrome
Stress, Inflammation, and Mood: A Role for Leptin?
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Prior research has suggested a possible role for the proinflammatory adipokine leptin in depression. Leptin has also been associated with stress, a known predictor of depression. The purpose of this project was to investigate associations between stress, leptin, and depressed mood. We used data from a larger observational study that collected daily levels of plasma leptin and self-reported stress and depressed mood from 55 women over 25 days. Women with and without chronic fatigue syndrome (CFS) were included. We hypothesized the following: increased stress would be associated with both worsened mood and higher leptin, and that leptin would be positively associated with depressed mood. Vitamin D was also explored as a potential moderating factor. Linear mixed models were used to analyze associations between daily stress, leptin, and mood at a 1-day time lag. Results suggested an association between stress and next-day leptin, dependent on vitamin D level (p = .018). Leptin also varied by patient group depending on vitamin D (p = .018), with highest leptin observed among women with CFS and lower vitamin D (< 20 ng/mL). Overall, findings support further investigation of vitamin D in relation to stress and leptin; leptin, however, does not appear to play a substantial role in depressed mood.
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