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Inhibitory effects of cellulose and nonprovitamin A carotenoids on beta-carotene utilization in rats.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Inhibitory effects of cellulose and nonprovitamin A carotenoids on beta-carotene utilization in rats./
作者:	Huang, Shih-I.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 1995,
面頁冊數:	128 p.
附註:	Source: Dissertations Abstracts International, Volume: 57-06, Section: B.
Contained By:	Dissertations Abstracts International57-06B.
標題:	Nutrition. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=9601846
ISBN:	9798209267270

Inhibitory effects of cellulose and nonprovitamin A carotenoids on beta-carotene utilization in rats.
Huang, Shih-I.

Inhibitory effects of cellulose and nonprovitamin A carotenoids on beta-carotene utilization in rats. - Ann Arbor : ProQuest Dissertations & Theses, 1995 - 128 p.

Source: Dissertations Abstracts International, Volume: 57-06, Section: B.

Thesis (Ph.D.)--University of Rhode Island, 1995.

This item must not be sold to any third party vendors.

Inhibitory effects of cellulose (Celufil) and lutein on the rats fed with 0.1% $\\beta$-carotene were investigated. Using the HPLC, the retinol concentration of the liver in response to the various cellulose level in diets were significantly difference. The more the cellulose intake, the less the vitamin A storage in the liver. In the small intestine and kidney, the retinol concentrations were higher in the non-Celufil group. Statistically, serum retinol levels were not altered by feeding cellulose in the 8-week study. The retinol concentrations in sera were reduced by cellulose (Celufil) and lutein in a 3-day experiment. The result of this study confirmed that $\\beta$-carotene was converted by not only central cleavage but also excentric cleavage. Retinoids and $\\beta$-apo-carotenals, including retinal, $\\beta$-apo-12$\\sp\\prime$-, -8$\\sp\\prime$-carotenal and two major unknown compounds (R340-5 & C450-7), were found in a three-hour incubation of $\\beta$-carotene with intestinal mucosa homogenate. The specific enzyme activity of intestinal mucosa homogenate on retinoids formation was also measured. The maximum production of retinoids (retinal and R340-5) was in the first hour. The formation rate of retinal and R340-5 were 2.11 to 2.54% and 1.20 to 1.50%, respectively. Effect of lutein and lycopene on retinoids formation was evaluated. The formation of retinoids was inhibited in high doses of lutein and lycopene. The retinal formation was significantly depressed by low doses of lutein (44%) and by high doses of lutein (65%) compared with the no lutein group. In the low doses of lycopene experiment, there was no significant inhibition on retinal and R340-5 formation. However, the formation of retinoids was inhibited by high doses of lycopene.

ISBN: 9798209267270Subjects--Topical Terms:

517777
Nutrition.
Subjects--Index Terms:

Vitamin A

Inhibitory effects of cellulose and nonprovitamin A carotenoids on beta-carotene utilization in rats.
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500 $a Source: Dissertations Abstracts International, Volume: 57-06, Section: B.
500 $a Publisher info.: Dissertation/Thesis.
500 $a Advisor: Simpson, K.L.
502 $a Thesis (Ph.D.)--University of Rhode Island, 1995.
506 $a This item must not be sold to any third party vendors.
506 $a This item must not be added to any third party search indexes.
520 $a Inhibitory effects of cellulose (Celufil) and lutein on the rats fed with 0.1% $\\beta$-carotene were investigated. Using the HPLC, the retinol concentration of the liver in response to the various cellulose level in diets were significantly difference. The more the cellulose intake, the less the vitamin A storage in the liver. In the small intestine and kidney, the retinol concentrations were higher in the non-Celufil group. Statistically, serum retinol levels were not altered by feeding cellulose in the 8-week study. The retinol concentrations in sera were reduced by cellulose (Celufil) and lutein in a 3-day experiment. The result of this study confirmed that $\\beta$-carotene was converted by not only central cleavage but also excentric cleavage. Retinoids and $\\beta$-apo-carotenals, including retinal, $\\beta$-apo-12$\\sp\\prime$-, -8$\\sp\\prime$-carotenal and two major unknown compounds (R340-5 & C450-7), were found in a three-hour incubation of $\\beta$-carotene with intestinal mucosa homogenate. The specific enzyme activity of intestinal mucosa homogenate on retinoids formation was also measured. The maximum production of retinoids (retinal and R340-5) was in the first hour. The formation rate of retinal and R340-5 were 2.11 to 2.54% and 1.20 to 1.50%, respectively. Effect of lutein and lycopene on retinoids formation was evaluated. The formation of retinoids was inhibited in high doses of lutein and lycopene. The retinal formation was significantly depressed by low doses of lutein (44%) and by high doses of lutein (65%) compared with the no lutein group. In the low doses of lycopene experiment, there was no significant inhibition on retinal and R340-5 formation. However, the formation of retinoids was inhibited by high doses of lycopene.
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