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A practical guide to drug developmen...

Mochly-Rosen, Daria.

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A practical guide to drug development in academia = the SPARK approach /

Record Type:	Electronic resources : Monograph/item
Title/Author:	A practical guide to drug development in academia/ edited by Daria Mochly-Rosen, Kevin Grimes.
Reminder of title:	the SPARK approach /
other author:	Mochly-Rosen, Daria.
Published:	Cham :Springer International Publishing : : 2023.,
Description:	xiii, 267 p. :ill. (some col.), digital ;24 cm.
Contained By:	Springer Nature eBook
Subject:	Drug development - Handbooks, manuals, etc. -
Online resource:	https://doi.org/10.1007/978-3-031-34724-5
ISBN:	9783031347245

A practical guide to drug development in academia = the SPARK approach /
A practical guide to drug development in academiathe SPARK approach /[electronic resource] :edited by Daria Mochly-Rosen, Kevin Grimes. - Second edition. - Cham :Springer International Publishing :2023. - xiii, 267 p. :ill. (some col.), digital ;24 cm.

"A lot of hard-won knowledge is laid out here in a brief but informative way. Every topic is well referenced, with citations from both the primary literature and relevant resources from the internet." Review of first edition from Nature Chemical Biology Written by the founders of the SPARK program at Stanford University, this book is a practical guide designed for professors, students and clinicians at academic research institutions who are interested in learning more about the drug development process and how to start transforming their basic research discoveries into novel drugs. Often many potentially transformative basic science discoveries are not pursued because they are deemed 'too early' to attract industry interest. This comprehensive book lays out simple, relatively cost-effective things that academic researchers can do to advance their findings to the point that they can be tested in the clinic or attract more industry interest. Each chapter broadly discusses an important topic in drug development, from discovery, optimization and preclinical studies through clinical trial design, regulatory issues and marketing assessments. After the practical overview provided here, the reader is encouraged to consult more detailed texts on specific topics of interest. The SPARK model has been adopted in over 50 institutions on six continents, and the program has been honored with multiple awards including the 2020 Xconomy Award for Ecosystem Development, the 2020 Cures Within Reach Award for Patient Impact Research, and the 2022 California Life Sciences Pantheon Award for Academia, Non-Profits, & Research. The new edition updates every chapter with the latest developments since the 2014 publication of the first edition.

ISBN: 9783031347245

Standard No.: 10.1007/978-3-031-34724-5doiSubjects--Topical Terms:

726826
Drug development
--Handbooks, manuals, etc.

LC Class. No.: RM301.25

Dewey Class. No.: 615.19

A practical guide to drug development in academia = the SPARK approach /
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520 $a "A lot of hard-won knowledge is laid out here in a brief but informative way. Every topic is well referenced, with citations from both the primary literature and relevant resources from the internet." Review of first edition from Nature Chemical Biology Written by the founders of the SPARK program at Stanford University, this book is a practical guide designed for professors, students and clinicians at academic research institutions who are interested in learning more about the drug development process and how to start transforming their basic research discoveries into novel drugs. Often many potentially transformative basic science discoveries are not pursued because they are deemed 'too early' to attract industry interest. This comprehensive book lays out simple, relatively cost-effective things that academic researchers can do to advance their findings to the point that they can be tested in the clinic or attract more industry interest. Each chapter broadly discusses an important topic in drug development, from discovery, optimization and preclinical studies through clinical trial design, regulatory issues and marketing assessments. After the practical overview provided here, the reader is encouraged to consult more detailed texts on specific topics of interest. The SPARK model has been adopted in over 50 institutions on six continents, and the program has been honored with multiple awards including the 2020 Xconomy Award for Ecosystem Development, the 2020 Cures Within Reach Award for Patient Impact Research, and the 2022 California Life Sciences Pantheon Award for Academia, Non-Profits, & Research. The new edition updates every chapter with the latest developments since the 2014 publication of the first edition.
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