東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Antibody-drug conjugates and cellula...

Chen, Shuqing.

Linked to FindBook

Google Book

Amazon

博客來

Antibody-drug conjugates and cellular metabolic dynamics

Record Type:	Electronic resources : Monograph/item
Title/Author:	Antibody-drug conjugates and cellular metabolic dynamics/ edited by Shuqing Chen, Jinbiao Zhan.
other author:	Chen, Shuqing.
Published:	Singapore :Springer Nature Singapore : : 2023.,
Description:	ix, 135 p. :ill., digital ;24 cm.
[NT 15003449]:	Antibody-Drug Conjugates Basic Concepts and Structures -- Relationship between target and specific action of antibody-drugs conjugates -- The internalization and therapeutic activity of antibody drug conjugate -- The internalization and intracellular trafficking of ADC -- Distribution and metabolism of antibody-drug conjugates -- Application of Antibody fragments in ADCs -- Novel Targeting Carriers in Antibody-drug Conjugates -- Site-specified Conjugating Technology and Application -- Determination of drug-to-antibody ratio of ADCs -- Pharmacokinetic study of antibody-drug conjugates.
Contained By:	Springer Nature eBook
Subject:	Antibody-drug conjugates. -
Online resource:	https://doi.org/10.1007/978-981-19-5638-6
ISBN:	9789811956386

Antibody-drug conjugates and cellular metabolic dynamics
Antibody-drug conjugates and cellular metabolic dynamics[electronic resource] /edited by Shuqing Chen, Jinbiao Zhan. - Singapore :Springer Nature Singapore :2023. - ix, 135 p. :ill., digital ;24 cm.

Antibody-Drug Conjugates Basic Concepts and Structures -- Relationship between target and specific action of antibody-drugs conjugates -- The internalization and therapeutic activity of antibody drug conjugate -- The internalization and intracellular trafficking of ADC -- Distribution and metabolism of antibody-drug conjugates -- Application of Antibody fragments in ADCs -- Novel Targeting Carriers in Antibody-drug Conjugates -- Site-specified Conjugating Technology and Application -- Determination of drug-to-antibody ratio of ADCs -- Pharmacokinetic study of antibody-drug conjugates.

This book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs. This book combines the basic theory with the research technology. It can be used as a reference book for students, teachers and researchers of biomedical field.

ISBN: 9789811956386

Standard No.: 10.1007/978-981-19-5638-6doiSubjects--Topical Terms:

2139008
Antibody-drug conjugates.

LC Class. No.: RS201.A56 / A58 2023

Dewey Class. No.: 615.36

Antibody-drug conjugates and cellular metabolic dynamics
LDR:02738nmm a2200349 a 4500 001 2316737
003 DE-He213
005 20230418051944.0
006 m d
007 cr nn 008maaau
008 230902s2023 si s 0 eng d
020 $a 9789811956386 $q (electronic bk.)
020 $a 9789811956379 $q (paper)
024 7 $a 10.1007/978-981-19-5638-6 $2 doi
035 $a 978-981-19-5638-6
040 $a GP $c GP
041 0 $a eng
050 4 $a RS201.A56 $b A58 2023
072 7 $a PS $2 bicssc
072 7 $a PDN $2 bicssc
072 7 $a SCI008000 $2 bisacsh
072 7 $a PS $2 thema
072 7 $a PDN $2 thema
082 0 4 $a 615.36 $2 23
090 $a RS201.A56 $b A629 2023
245 1 0 $a Antibody-drug conjugates and cellular metabolic dynamics $h [electronic resource] / $c edited by Shuqing Chen, Jinbiao Zhan.
260 $a Singapore : $b Springer Nature Singapore : $b Imprint: Springer, $c 2023.
300 $a ix, 135 p. : $b ill., digital ; $c 24 cm.
505 0 $a Antibody-Drug Conjugates Basic Concepts and Structures -- Relationship between target and specific action of antibody-drugs conjugates -- The internalization and therapeutic activity of antibody drug conjugate -- The internalization and intracellular trafficking of ADC -- Distribution and metabolism of antibody-drug conjugates -- Application of Antibody fragments in ADCs -- Novel Targeting Carriers in Antibody-drug Conjugates -- Site-specified Conjugating Technology and Application -- Determination of drug-to-antibody ratio of ADCs -- Pharmacokinetic study of antibody-drug conjugates.
520 $a This book summarizes the related research achievements in Antibody-drug conjugates (ADCs) and their cell metabolism kinetics. The book has three main parts. The first part describes the basic theory of ADCs, including the basic concept and structure of ADCs, and the relationship between the targets of ADCs and their specific functions. The second part mainly introduces the endocytosis and intracellular metabolism of ADCs, including the relationship between endocytosis and ADC activity, the endocytosis and intracellular transport of ADCs, the distribution and metabolism of ADC in vivo. Then it discusses the new formats and research technology of ADCs, including the application of miniaturized antibodies in ADC synthesis, novel carriers for ADC design, the technology and application of site-specific conjugation, and approaches for analyzing the drug: antibody ratio (DAR), the study of pharmacokinetics of ADCs. This book combines the basic theory with the research technology. It can be used as a reference book for students, teachers and researchers of biomedical field.
650 0 $a Antibody-drug conjugates. $3 2139008
650 1 4 $a Immunological Techniques. $3 3627693
650 2 4 $a Pharmaceutics. $3 3538434
650 2 4 $a Biomedical Research. $3 851895
650 2 4 $a Cell Biology. $3 892383
650 2 4 $a Medical Biochemistry. $3 892387
700 1 $a Chen, Shuqing. $3 3630226
700 1 $a Zhan, Jinbiao. $3 3630227
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer Nature eBook
856 4 0 $u https://doi.org/10.1007/978-981-19-5638-6
950 $a Biomedical and Life Sciences (SpringerNature-11642)