語系:
繁體中文
English
說明(常見問題)
回圖書館首頁
手機版館藏查詢
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
Discovery of small-molecule modulato...
~
Byun, Wan Gi.
FindBook
Google Book
Amazon
博客來
Discovery of small-molecule modulators of protein-RNA interactions for treating cancer and COVID-19
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Discovery of small-molecule modulators of protein-RNA interactions for treating cancer and COVID-19/ by Wan Gi Byun.
作者:
Byun, Wan Gi.
出版者:
Singapore :Springer Nature Singapore : : 2023.,
面頁冊數:
xxxii, 128 p. :ill., digital ;24 cm.
附註:
"Doctoral thesis accepted by Seoul National University, Seoul, Korea (Republic of)"
內容註:
1. Introduction -- 2. Identification of Small-Molecule Inhibitors of Oncogenic Lin28-Let-7 Interaction -- 3. Discovery of Small-Molecule Modulators of Protein-RNA Interactions by Fluorescence Intensity-Based Binding Assay -- 4. Harnessing Stress Granule Formation by Small Molecules to Inhibit the Cellular Replication of SARS-CoV-2 -- Appendix.
Contained By:
Springer Nature eBook
標題:
RNA-protein interactions. -
電子資源:
https://doi.org/10.1007/978-981-19-7814-2
ISBN:
9789811978142
Discovery of small-molecule modulators of protein-RNA interactions for treating cancer and COVID-19
Byun, Wan Gi.
Discovery of small-molecule modulators of protein-RNA interactions for treating cancer and COVID-19
[electronic resource] /by Wan Gi Byun. - Singapore :Springer Nature Singapore :2023. - xxxii, 128 p. :ill., digital ;24 cm. - Springer theses,2190-5061. - Springer theses..
"Doctoral thesis accepted by Seoul National University, Seoul, Korea (Republic of)"
1. Introduction -- 2. Identification of Small-Molecule Inhibitors of Oncogenic Lin28-Let-7 Interaction -- 3. Discovery of Small-Molecule Modulators of Protein-RNA Interactions by Fluorescence Intensity-Based Binding Assay -- 4. Harnessing Stress Granule Formation by Small Molecules to Inhibit the Cellular Replication of SARS-CoV-2 -- Appendix.
This book describes the development of novel protein-RNA-binding assays and their applications in a high-throughput manner for the identification of small-molecule modulators of protein-RNA interactions to treat cancer and COVID-19. Modulating protein-RNA interactions with small molecules is expected to provide novel biological insights of the interrelation of diseases with the protein-RNA interactome. The modulations may also be exploited therapeutically. For these reasons, the development of a simple, reliable, and sensitive protein-RNA-binding assay is necessary for high-throughput screening to discover new effective chemical entities capable of acting on diverse protein-RNA interactions. This book discusses the discovery of small-molecule modulators targeting protein-RNA interactions that are potentially valuable to treat cancer and COVID-19 by constructing novel high-throughput screening methods. The results of this dissertation provide valuable insights into the regulation of protein-RNA interactions in chemical biology and drug development.
ISBN: 9789811978142
Standard No.: 10.1007/978-981-19-7814-2doiSubjects--Topical Terms:
569547
RNA-protein interactions.
LC Class. No.: QP623.8.P75 / B98 2023
Dewey Class. No.: 572.633
Discovery of small-molecule modulators of protein-RNA interactions for treating cancer and COVID-19
LDR
:02572nmm a2200349 a 4500
001
2314750
003
DE-He213
005
20221213201814.0
006
m d
007
cr nn 008mamaa
008
230902s2023 si s 0 eng d
020
$a
9789811978142
$q
(electronic bk.)
020
$a
9789811978135
$q
(paper)
024
7
$a
10.1007/978-981-19-7814-2
$2
doi
035
$a
978-981-19-7814-2
040
$a
GP
$c
GP
041
0
$a
eng
050
4
$a
QP623.8.P75
$b
B98 2023
072
7
$a
T
$2
bicssc
072
7
$a
SCI009000
$2
bisacsh
072
7
$a
T
$2
thema
082
0 4
$a
572.633
$2
23
090
$a
QP623.8.P75
$b
B998 2023
100
1
$a
Byun, Wan Gi.
$3
3626441
245
1 0
$a
Discovery of small-molecule modulators of protein-RNA interactions for treating cancer and COVID-19
$h
[electronic resource] /
$c
by Wan Gi Byun.
260
$a
Singapore :
$b
Springer Nature Singapore :
$b
Imprint: Springer,
$c
2023.
300
$a
xxxii, 128 p. :
$b
ill., digital ;
$c
24 cm.
490
1
$a
Springer theses,
$x
2190-5061
500
$a
"Doctoral thesis accepted by Seoul National University, Seoul, Korea (Republic of)"
505
0
$a
1. Introduction -- 2. Identification of Small-Molecule Inhibitors of Oncogenic Lin28-Let-7 Interaction -- 3. Discovery of Small-Molecule Modulators of Protein-RNA Interactions by Fluorescence Intensity-Based Binding Assay -- 4. Harnessing Stress Granule Formation by Small Molecules to Inhibit the Cellular Replication of SARS-CoV-2 -- Appendix.
520
$a
This book describes the development of novel protein-RNA-binding assays and their applications in a high-throughput manner for the identification of small-molecule modulators of protein-RNA interactions to treat cancer and COVID-19. Modulating protein-RNA interactions with small molecules is expected to provide novel biological insights of the interrelation of diseases with the protein-RNA interactome. The modulations may also be exploited therapeutically. For these reasons, the development of a simple, reliable, and sensitive protein-RNA-binding assay is necessary for high-throughput screening to discover new effective chemical entities capable of acting on diverse protein-RNA interactions. This book discusses the discovery of small-molecule modulators targeting protein-RNA interactions that are potentially valuable to treat cancer and COVID-19 by constructing novel high-throughput screening methods. The results of this dissertation provide valuable insights into the regulation of protein-RNA interactions in chemical biology and drug development.
650
0
$a
RNA-protein interactions.
$3
569547
650
0
$a
Cancer
$x
Genetic aspects.
$3
669248
650
0
$a
Cancer
$x
Molecular aspects.
$3
661419
650
0
$a
COVID-19 (Disease)
$x
Genetic aspects.
$3
3626442
650
0
$a
COVID-19 (Disease)
$x
Molecular aspects.
$3
3490515
650
1 4
$a
Biological and Physical Engineering.
$3
3626015
650
2 4
$a
Chemical Bioengineering.
$3
3591613
650
2 4
$a
Biophysics.
$3
518360
650
2 4
$a
Protein Folding.
$3
916838
650
2 4
$a
RNA Interference.
$3
753203
710
2
$a
SpringerLink (Online service)
$3
836513
773
0
$t
Springer Nature eBook
830
0
$a
Springer theses.
$3
1314442
856
4 0
$u
https://doi.org/10.1007/978-981-19-7814-2
950
$a
Engineering (SpringerNature-11647)
筆 0 讀者評論
館藏地:
全部
電子資源
出版年:
卷號:
館藏
1 筆 • 頁數 1 •
1
條碼號
典藏地名稱
館藏流通類別
資料類型
索書號
使用類型
借閱狀態
預約狀態
備註欄
附件
W9451000
電子資源
11.線上閱覽_V
電子書
EB QP623.8.P75 B98 2023
一般使用(Normal)
在架
0
1 筆 • 頁數 1 •
1
多媒體
評論
新增評論
分享你的心得
Export
取書館
處理中
...
變更密碼
登入