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Combating Bacterial Antibiotic Resis...

MacKnight, Michael A.

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Combating Bacterial Antibiotic Resistance Through the Investigation and Inhibition of Peptidoglycan Synthesis.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Combating Bacterial Antibiotic Resistance Through the Investigation and Inhibition of Peptidoglycan Synthesis./
作者:	MacKnight, Michael A.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2021,
面頁冊數:	67 p.
附註:	Source: Masters Abstracts International, Volume: 82-08.
Contained By:	Masters Abstracts International82-08.
標題:	Organic chemistry. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28264653
ISBN:	9798569963034

Combating Bacterial Antibiotic Resistance Through the Investigation and Inhibition of Peptidoglycan Synthesis.
MacKnight, Michael A.

Combating Bacterial Antibiotic Resistance Through the Investigation and Inhibition of Peptidoglycan Synthesis. - Ann Arbor : ProQuest Dissertations & Theses, 2021 - 67 p.

Source: Masters Abstracts International, Volume: 82-08.

Thesis (M.S.)--Indiana University, 2021.

This item must not be sold to any third party vendors.

The alarming increase of bacterial resistance to commercially available antibiotics has become a global health concern. In an effort to combat this problem, a deeper understanding of bacterial life processes is required, and compounds that disrupt these processes through novel mechanisms of action should be investigated. Improving the efficiency of synthesis of one such compound, lysobactin, is focused on increasing the availability of this compound for biological studies. Additionally, the synthesis of a tool of study for peptidoglycan synthesis in the form of a Fluorescent D-Amino Acid, Fluoremidine-D-Lysine, serves to expand the potential for studying peptidoglycan synthesis.

ISBN: 9798569963034Subjects--Topical Terms:

523952
Organic chemistry.
Subjects--Index Terms:

Bacterial antibiotic resistance

Combating Bacterial Antibiotic Resistance Through the Investigation and Inhibition of Peptidoglycan Synthesis.
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500 $a Source: Masters Abstracts International, Volume: 82-08.
500 $a Advisor: VanNieuwenhze, Michael S.
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506 $a This item must not be sold to any third party vendors.
520 $a The alarming increase of bacterial resistance to commercially available antibiotics has become a global health concern. In an effort to combat this problem, a deeper understanding of bacterial life processes is required, and compounds that disrupt these processes through novel mechanisms of action should be investigated. Improving the efficiency of synthesis of one such compound, lysobactin, is focused on increasing the availability of this compound for biological studies. Additionally, the synthesis of a tool of study for peptidoglycan synthesis in the form of a Fluorescent D-Amino Acid, Fluoremidine-D-Lysine, serves to expand the potential for studying peptidoglycan synthesis.
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