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Advancements in Stimulated Raman Sca...

Figueroa, Benjamin, Jr.

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Advancements in Stimulated Raman Scattering Microscopy.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Advancements in Stimulated Raman Scattering Microscopy./
作者:	Figueroa, Benjamin, Jr.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2020,
面頁冊數:	147 p.
附註:	Source: Dissertations Abstracts International, Volume: 82-08, Section: B.
Contained By:	Dissertations Abstracts International82-08B.
標題:	Optics. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28259333
ISBN:	9798569995318

Advancements in Stimulated Raman Scattering Microscopy.
Figueroa, Benjamin, Jr.

Advancements in Stimulated Raman Scattering Microscopy. - Ann Arbor : ProQuest Dissertations & Theses, 2020 - 147 p.

Source: Dissertations Abstracts International, Volume: 82-08, Section: B.

Thesis (Ph.D.)--University of Washington, 2020.

This item must not be sold to any third party vendors.

Stimulated Raman scattering (SRS) microscopy has transformed our ability to image chemical and biological systems because of its sub-micrometer resolution and molecular specificity. However, limitations in small spectral coverage, poor spectral resolution, and low sensitivity hamper the ability of SRS to investigate complex systems. Furthermore, the usage of SRS microscopy beyond biological systems is still very limited.Here I present my work which specifically addresses these issues. In chapters 2 and 3 I demonstrate the benefits of using SRS microscopy outside of its current biological niche, by investigating materials such as latent fingerprints and pharmaceutical tablets. In chapter 4 I address the limitations of poor spectral resolution and small spectral coverage by developing a parabolic fiber amplifier to provide a better SRS microscope. In chapter 5 I demonstrate an application of the developed fiber amplifier system for monitoring and quantifying temperature at the microscale level. Lastly, in chapter 6 I introduce the development of a new optical parametric oscillator (OPO) source to address the final limitation by increasing the sensitivity of SRS imaging, which ties into the future outlook on advancements needed in SRS microscopy.

ISBN: 9798569995318Subjects--Topical Terms:

517925
Optics.
Subjects--Index Terms:

Laser engineering

Advancements in Stimulated Raman Scattering Microscopy.
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245 1 0 $a Advancements in Stimulated Raman Scattering Microscopy.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2020
300 $a 147 p.
500 $a Source: Dissertations Abstracts International, Volume: 82-08, Section: B.
500 $a Advisor: Fu, Dan.
502 $a Thesis (Ph.D.)--University of Washington, 2020.
506 $a This item must not be sold to any third party vendors.
520 $a Stimulated Raman scattering (SRS) microscopy has transformed our ability to image chemical and biological systems because of its sub-micrometer resolution and molecular specificity. However, limitations in small spectral coverage, poor spectral resolution, and low sensitivity hamper the ability of SRS to investigate complex systems. Furthermore, the usage of SRS microscopy beyond biological systems is still very limited.Here I present my work which specifically addresses these issues. In chapters 2 and 3 I demonstrate the benefits of using SRS microscopy outside of its current biological niche, by investigating materials such as latent fingerprints and pharmaceutical tablets. In chapter 4 I address the limitations of poor spectral resolution and small spectral coverage by developing a parabolic fiber amplifier to provide a better SRS microscope. In chapter 5 I demonstrate an application of the developed fiber amplifier system for monitoring and quantifying temperature at the microscale level. Lastly, in chapter 6 I introduce the development of a new optical parametric oscillator (OPO) source to address the final limitation by increasing the sensitivity of SRS imaging, which ties into the future outlook on advancements needed in SRS microscopy.
590 $a School code: 0250.
650 4 $a Optics. $3 517925
650 4 $a Physics. $3 516296
653 $a Laser engineering
653 $a Microscopy
653 $a Stimulated Raman Spectroscopy
690 $a 0752
690 $a 0605
710 2 $a University of Washington. $b Chemistry. $3 2093573
773 0 $t Dissertations Abstracts International $g 82-08B.
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791 $a Ph.D.
792 $a 2020
793 $a English
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