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The Role of Dietary Patterns in Chro...

Hu, Emily A.

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The Role of Dietary Patterns in Chronic Kidney Disease Incidence and Progression.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The Role of Dietary Patterns in Chronic Kidney Disease Incidence and Progression./
作者:	Hu, Emily A.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2020,
面頁冊數:	147 p.
附註:	Source: Dissertations Abstracts International, Volume: 82-03, Section: B.
Contained By:	Dissertations Abstracts International82-03B.
標題:	Public health. -
電子資源:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=28068768
ISBN:	9798662429734

The Role of Dietary Patterns in Chronic Kidney Disease Incidence and Progression.
Hu, Emily A.

The Role of Dietary Patterns in Chronic Kidney Disease Incidence and Progression. - Ann Arbor : ProQuest Dissertations & Theses, 2020 - 147 p.

Source: Dissertations Abstracts International, Volume: 82-03, Section: B.

Thesis (Ph.D.)--The Johns Hopkins University, 2020.

This item must not be sold to any third party vendors.

This dissertation was designed to examine imperative questions related to the role of dietary patterns in chronic kidney disease (CKD) incidence and progression. We sought to examine whether adherence to dietary patterns is associated with kidney disease and its progression using two datasets, the Atherosclerosis Risk in Communities (ARIC) Study, and the Chronic Renal Insufficiency Cohort (CRIC) Study. First, we examined the association between three diet quality indices, the Healthy Eating Index-2015 (HEI-2015), Alternative Healthy Eating Index-2010 (AHEI-2010), and alternate Mediterranean (aMed) diet scores, and risk of incident CKD among generally healthy participants in the ARIC Study. Compared with participants in quintile 1 of each dietary score, participants in quintile 5 of HEI-2015, AHEI-2010, and aMed had, respectively, a 17%, 20%, and 13% lower risk of incident CKD. Second, we examined the association between the HEI-2015, AHEI-2010, aMed, and Dietary Approaches to Stop Hypertension (DASH) scores and risk of CKD progression and all-cause mortality among people with CKD from the CRIC Study. We found that compared with participants who were in tertile 1, participants in tertile 3 of AHEI-2010, aMed, and DASH scores had lower risk of CKD progression, with the strongest results for aMed (hazard ratio: 0.75, 95% confidence interval: 0.62-0.90). Highest adherence for all four scores was associated with 24-31% lower risk of all-cause mortality compared with lowest adherence. Third, we created a novel index, the Healthy Beverage Score, to characterize the quality of beverage patterns and examined its association with CKD progression and all-cause mortality among people with CKD in the CRIC Study. Compared with participants in the lowest tertile of the score, participants in the highest tertile had a 27% lower risk of CKD progression and 17% lower risk of all-cause mortality. These findings suggest that 1) dietary modification can be used as primary and secondary prevention strategies to reduce risk of CKD incidence and CKD progression; and 2) beverage intake may be an important modifiable target to manage adverse health outcomes among people with CKD. This dissertation extends current knowledge on the role of dietary patterns in chronic disease prevention and management.

ISBN: 9798662429734Subjects--Topical Terms:

534748
Public health.
Subjects--Index Terms:

Diet

The Role of Dietary Patterns in Chronic Kidney Disease Incidence and Progression.
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