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Engineered MEMS Microenvironments fo...
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Perebikovsky, Alexandra.
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Engineered MEMS Microenvironments for Studying Stem Cells and Microorganisms.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Engineered MEMS Microenvironments for Studying Stem Cells and Microorganisms./
作者:
Perebikovsky, Alexandra.
出版者:
Ann Arbor : ProQuest Dissertations & Theses, : 2020,
面頁冊數:
199 p.
附註:
Source: Dissertations Abstracts International, Volume: 82-02, Section: B.
Contained By:
Dissertations Abstracts International82-02B.
標題:
Physics. -
電子資源:
https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27998856
ISBN:
9798662428393
Engineered MEMS Microenvironments for Studying Stem Cells and Microorganisms.
Perebikovsky, Alexandra.
Engineered MEMS Microenvironments for Studying Stem Cells and Microorganisms.
- Ann Arbor : ProQuest Dissertations & Theses, 2020 - 199 p.
Source: Dissertations Abstracts International, Volume: 82-02, Section: B.
Thesis (Ph.D.)--University of California, Irvine, 2020.
This item must not be sold to any third party vendors.
Advances in miniaturization and nanofabrication techniques have led to significant medical breakthroughs, especially in the fields of stem cell therapy and medical diagnostics. In this contribution, we use MEMS techniques to develop two different tools that allow us to study different biological organisms: 1.) a multi-functional smart scaffold for studying stem cells, and 2.) a centrifugal microfluidic platform for studying microorganisms like bacteria. In Part II, we use the multi-functional smart scaffold to control neural stem cell growth/differentiation and simultaneously monitor Dopamine released from the cells. In Part III, we use the centrifugal microfluidic platform to optimize the incubation of multiple bacteria species. We then use the same platform to develop a sample-to-answer phenotypic antibiotic susceptbility test that successfully identifies resistance in 11 different species of E. Coli in under 2 hours.
ISBN: 9798662428393Subjects--Topical Terms:
516296
Physics.
Subjects--Index Terms:
Antibiotics
Engineered MEMS Microenvironments for Studying Stem Cells and Microorganisms.
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