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The Prevalence and One Year Incidenc...
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Yancey, Julia Ann.
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The Prevalence and One Year Incidence of Frontotemporal Dementia in Individuals with Amyotrophic Lateral Sclerosis Based on Race.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
The Prevalence and One Year Incidence of Frontotemporal Dementia in Individuals with Amyotrophic Lateral Sclerosis Based on Race./
作者:
Yancey, Julia Ann.
出版者:
Ann Arbor : ProQuest Dissertations & Theses, : 2020,
面頁冊數:
67 p.
附註:
Source: Masters Abstracts International, Volume: 81-12.
Contained By:
Masters Abstracts International81-12.
標題:
Neurosciences. -
電子資源:
https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27961986
ISBN:
9798641085043
The Prevalence and One Year Incidence of Frontotemporal Dementia in Individuals with Amyotrophic Lateral Sclerosis Based on Race.
Yancey, Julia Ann.
The Prevalence and One Year Incidence of Frontotemporal Dementia in Individuals with Amyotrophic Lateral Sclerosis Based on Race.
- Ann Arbor : ProQuest Dissertations & Theses, 2020 - 67 p.
Source: Masters Abstracts International, Volume: 81-12.
Thesis (M.S.)--Wake Forest University, 2020.
This item must not be sold to any third party vendors.
Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with progressive loss of upper and lower motor neurons, whereas frontotemporal dementia (FTD) is a progressive dementing condition characterized by selective degeneration of the frontal and anterior temporal lobes. A link between ALS and FTD is well-established, and case studies document a strong association between amyotrophic lateral sclerosis and the behavioral form of FTD. A retrospective cohort study was conducted from patients visits to the Wake Forest School of Medicine. Individuals with ALS were identified from Epic chart review from the past ten years. The charts were matched, Caucasian to African-American patients, regarding the following variables: race, age, and site of onset. Cognitive behavioral screen (CBS) scores were collected from all cases and compared between Caucasian and African American cohorts. In the Epic database there are 36 African-Americans patients and 102 Caucasian patients that received ALS-CBS testing. The CBS scores were reviewed and we performed logistic regression to compare their scores. No clear association was found between CBS scores and race in individuals with ALS, although after controlling for multiple variables some patterns arose suggesting lower CBS scores in African Americans. The evolving knowledge of the links between ALS and FTD has allowed for better understanding of how these conditions affect each other. Determining the prevalence of FTD in different races may provide insight regarding who is at risk, and it may also impact how physicians recognize and treat dementia in those with ALS.
ISBN: 9798641085043Subjects--Topical Terms:
588700
Neurosciences.
Subjects--Index Terms:
Frontotemporal dementia
The Prevalence and One Year Incidence of Frontotemporal Dementia in Individuals with Amyotrophic Lateral Sclerosis Based on Race.
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Amyotrophic lateral sclerosis (ALS) is a motor neuron disease with progressive loss of upper and lower motor neurons, whereas frontotemporal dementia (FTD) is a progressive dementing condition characterized by selective degeneration of the frontal and anterior temporal lobes. A link between ALS and FTD is well-established, and case studies document a strong association between amyotrophic lateral sclerosis and the behavioral form of FTD. A retrospective cohort study was conducted from patients visits to the Wake Forest School of Medicine. Individuals with ALS were identified from Epic chart review from the past ten years. The charts were matched, Caucasian to African-American patients, regarding the following variables: race, age, and site of onset. Cognitive behavioral screen (CBS) scores were collected from all cases and compared between Caucasian and African American cohorts. In the Epic database there are 36 African-Americans patients and 102 Caucasian patients that received ALS-CBS testing. The CBS scores were reviewed and we performed logistic regression to compare their scores. No clear association was found between CBS scores and race in individuals with ALS, although after controlling for multiple variables some patterns arose suggesting lower CBS scores in African Americans. The evolving knowledge of the links between ALS and FTD has allowed for better understanding of how these conditions affect each other. Determining the prevalence of FTD in different races may provide insight regarding who is at risk, and it may also impact how physicians recognize and treat dementia in those with ALS.
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