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Comparison of Social-communication i...

Geiser, Mary.

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Comparison of Social-communication in Individuals with Fragile X Syndrome and Williams Syndrome.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Comparison of Social-communication in Individuals with Fragile X Syndrome and Williams Syndrome./
Author:	Geiser, Mary.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2020,
Description:	58 p.
Notes:	Source: Masters Abstracts International, Volume: 81-11.
Contained By:	Masters Abstracts International81-11.
Subject:	Speech therapy. -
Online resource:	https://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27740262
ISBN:	9798645454517

Comparison of Social-communication in Individuals with Fragile X Syndrome and Williams Syndrome.
Geiser, Mary.

Comparison of Social-communication in Individuals with Fragile X Syndrome and Williams Syndrome. - Ann Arbor : ProQuest Dissertations & Theses, 2020 - 58 p.

Source: Masters Abstracts International, Volume: 81-11.

Thesis (M.S.)--Rush University, 2020.

This item must not be sold to any third party vendors.

Fragile X Syndrome (FXS) is a monogenetic syndrome that results from a mutation on the FMR1 gene on the X-chromosome. Williams Syndrome (WS) is a neurodevelopmental disorder caused by the deletion of twenty-six genes on chromosome 7. Both syndromes have increased risk of diagnosis of intellectual disability and Autism Spectrum Disorder. Despite these similarities, individuals with FXS present with reduced engagement in social interactions, whereas individuals with WS present with a hypersocial drive to engage with others. While the profiles of these two syndromes are well established, there is little to no research comparing the S-C profiles. This study used caregiver report to compare S-C profiles between FXS and WS, and examine how they compare to the NT profile, as well as examine if a diagnosis of FXS or WS determines the S-C profile, or if the profile is determined by a different factor. The Children's Communication Checklist-Second Edition measured the S-C profiles of each participant. SPSS analyses and latent profile analysis was used to examine the S-C profiles of each group. Results of these analyses revealed a splintered structural profile, but a consistent pragmatic profile among the group with FXS, and a globally reduced structural and pragmatic profile among the group with WS. S-C profiles were determined by overall language ability, as well as level of intellectual disability. Analyses did not reveal that S-C profiles were determined by diagnosis.

ISBN: 9798645454517Subjects--Topical Terms:

520446
Speech therapy.
Subjects--Index Terms:

Caregiver report

Comparison of Social-communication in Individuals with Fragile X Syndrome and Williams Syndrome.
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245 1 0 $a Comparison of Social-communication in Individuals with Fragile X Syndrome and Williams Syndrome.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2020
300 $a 58 p.
500 $a Source: Masters Abstracts International, Volume: 81-11.
500 $a Advisor: Hoffmann, Anne.
502 $a Thesis (M.S.)--Rush University, 2020.
506 $a This item must not be sold to any third party vendors.
520 $a Fragile X Syndrome (FXS) is a monogenetic syndrome that results from a mutation on the FMR1 gene on the X-chromosome. Williams Syndrome (WS) is a neurodevelopmental disorder caused by the deletion of twenty-six genes on chromosome 7. Both syndromes have increased risk of diagnosis of intellectual disability and Autism Spectrum Disorder. Despite these similarities, individuals with FXS present with reduced engagement in social interactions, whereas individuals with WS present with a hypersocial drive to engage with others. While the profiles of these two syndromes are well established, there is little to no research comparing the S-C profiles. This study used caregiver report to compare S-C profiles between FXS and WS, and examine how they compare to the NT profile, as well as examine if a diagnosis of FXS or WS determines the S-C profile, or if the profile is determined by a different factor. The Children's Communication Checklist-Second Edition measured the S-C profiles of each participant. SPSS analyses and latent profile analysis was used to examine the S-C profiles of each group. Results of these analyses revealed a splintered structural profile, but a consistent pragmatic profile among the group with FXS, and a globally reduced structural and pragmatic profile among the group with WS. S-C profiles were determined by overall language ability, as well as level of intellectual disability. Analyses did not reveal that S-C profiles were determined by diagnosis.
590 $a School code: 0821.
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653 $a Caregiver report
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653 $a Genetic disorders
653 $a Social communication
653 $a Williams syndrome
690 $a 0460
710 2 $a Rush University. $b Speech-Language Pathology. $3 3554753
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