東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Disinfection By-Products: Method Opt...

Cuthbertson, Amy A.

FindBook

Google Book

Amazon

博客來

Disinfection By-Products: Method Optimization for Quantification, Unknown Analysis, and Calculated Toxicity.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Disinfection By-Products: Method Optimization for Quantification, Unknown Analysis, and Calculated Toxicity./
作者:	Cuthbertson, Amy A.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2019,
面頁冊數:	263 p.
附註:	Source: Dissertations Abstracts International, Volume: 81-05, Section: B.
Contained By:	Dissertations Abstracts International81-05B.
標題:	Chemistry. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=13897837
ISBN:	9781687952677

Disinfection By-Products: Method Optimization for Quantification, Unknown Analysis, and Calculated Toxicity.
Cuthbertson, Amy A.

Disinfection By-Products: Method Optimization for Quantification, Unknown Analysis, and Calculated Toxicity. - Ann Arbor : ProQuest Dissertations & Theses, 2019 - 263 p.

Source: Dissertations Abstracts International, Volume: 81-05, Section: B.

Thesis (Ph.D.)--University of South Carolina, 2019.

This item must not be sold to any third party vendors.

Disinfected drinking water contains hundreds of disinfection by-products (DBPs) that are formed by the reaction of disinfectants with natural and anthropogenic organic matter, bromide, and iodide. Understanding what these DBPs are is important because millions of people worldwide consume drinking water every day, and human epidemiologic studies have reported cancer, miscarriage, and birth defects from consuming such waters. While more than 700 DBPs are reported in the literature, very few studies quantify complete classes of chlorinated, brominated, and iodinated DBPs. The following document contains five chapters in the format designated for specific scientific journals on this subject. Chapter 1 describes an optimized extraction method that combines 61 disinfection by-products from 7 different chemical classes prioritized by in vivo toxicity, and includes regulated trihalomethanes (THMs) and haloacetic acids (HAAs), unregulated iodinated HAAs and THMs, tri-haloacetaldehydes, haloketones, haloacetonitriles, halonitromethanes, and haloacetamides. Chapter 2 describes a novel method developed for the quantification of 10 halobenzoquinones (HBQs), a class of DBPs in drinking water which have been shown to be more toxic than most regulated DBPs. This method allows low ng/L limits of detection, requires minimal sample preparation, and analysis is almost entirely automated.Chapter 3 discusses a method that simultaneously quantifies DBPs, and analyzes unknown DBPs under full-scan conditions using a new type of time-of-flight (TOF) mass spectrometer, which combines selected ion monitoring (SIM)-level sensitivity with mass accuracy of ± 0.05 Da. Chapter 4 evaluates the reduction of 70 priority unregulated and regulated DBPs in full-scale chlorinated drinking plants using granular activated carbon (GAC), while assessing calculated cytotoxicity and genotoxicity. Chapter 5 evaluates the reduction of these priority unregulated DBPs, regulated DBPs, and N-nitrosodimethylamine (NDMA) in full-scale chloraminated drinking water plants that utilize biological activated carbon, while assessing calculated cytotoxicity and genotoxicity. Chapter 4 and 5 provide valuable insight into how to reduce these toxic unregulated DBPs, and what DBPs are toxicity-drivers in real-world exposure conditions. Chapter 1 is in the format of the journal, Analytical Chemistry; Chapter 2: Journal of Chromatography A; Chapter 3: Water Research; Chapter 4: Environmental Science & Technology; Chapter 5: Water Research.

ISBN: 9781687952677Subjects--Topical Terms:

516420
Chemistry.
Subjects--Index Terms:

Disinfection by-products

Disinfection By-Products: Method Optimization for Quantification, Unknown Analysis, and Calculated Toxicity.
LDR:03918nmm a2200433 4500 001 2272614
005 20201105110137.5
008 220629s2019 ||||||||||||||||| ||eng d
020 $a 9781687952677
035 $a (MiAaPQ)AAI13897837
035 $a AAI13897837
040 $a MiAaPQ $c MiAaPQ
100 1 $a Cuthbertson, Amy A. $3 3550041
245 1 0 $a Disinfection By-Products: Method Optimization for Quantification, Unknown Analysis, and Calculated Toxicity.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2019
300 $a 263 p.
500 $a Source: Dissertations Abstracts International, Volume: 81-05, Section: B.
500 $a Advisor: Richardson, Susan D.
502 $a Thesis (Ph.D.)--University of South Carolina, 2019.
506 $a This item must not be sold to any third party vendors.
506 $a This item must not be added to any third party search indexes.
520 $a Disinfected drinking water contains hundreds of disinfection by-products (DBPs) that are formed by the reaction of disinfectants with natural and anthropogenic organic matter, bromide, and iodide. Understanding what these DBPs are is important because millions of people worldwide consume drinking water every day, and human epidemiologic studies have reported cancer, miscarriage, and birth defects from consuming such waters. While more than 700 DBPs are reported in the literature, very few studies quantify complete classes of chlorinated, brominated, and iodinated DBPs. The following document contains five chapters in the format designated for specific scientific journals on this subject. Chapter 1 describes an optimized extraction method that combines 61 disinfection by-products from 7 different chemical classes prioritized by in vivo toxicity, and includes regulated trihalomethanes (THMs) and haloacetic acids (HAAs), unregulated iodinated HAAs and THMs, tri-haloacetaldehydes, haloketones, haloacetonitriles, halonitromethanes, and haloacetamides. Chapter 2 describes a novel method developed for the quantification of 10 halobenzoquinones (HBQs), a class of DBPs in drinking water which have been shown to be more toxic than most regulated DBPs. This method allows low ng/L limits of detection, requires minimal sample preparation, and analysis is almost entirely automated.Chapter 3 discusses a method that simultaneously quantifies DBPs, and analyzes unknown DBPs under full-scan conditions using a new type of time-of-flight (TOF) mass spectrometer, which combines selected ion monitoring (SIM)-level sensitivity with mass accuracy of ± 0.05 Da. Chapter 4 evaluates the reduction of 70 priority unregulated and regulated DBPs in full-scale chlorinated drinking plants using granular activated carbon (GAC), while assessing calculated cytotoxicity and genotoxicity. Chapter 5 evaluates the reduction of these priority unregulated DBPs, regulated DBPs, and N-nitrosodimethylamine (NDMA) in full-scale chloraminated drinking water plants that utilize biological activated carbon, while assessing calculated cytotoxicity and genotoxicity. Chapter 4 and 5 provide valuable insight into how to reduce these toxic unregulated DBPs, and what DBPs are toxicity-drivers in real-world exposure conditions. Chapter 1 is in the format of the journal, Analytical Chemistry; Chapter 2: Journal of Chromatography A; Chapter 3: Water Research; Chapter 4: Environmental Science & Technology; Chapter 5: Water Research.
590 $a School code: 0202.
650 4 $a Chemistry. $3 516420
650 4 $a Environmental science. $3 677245
650 4 $a Hydrologic sciences. $3 3168407
650 4 $a Natural resource management. $3 589570
650 4 $a Water resources management. $3 794747
650 4 $a Public health. $3 534748
650 4 $a Toxicology. $3 556884
653 $a Disinfection by-products
653 $a Disinfected drinking water
653 $a Optimized extraction method
653 $a Unregulated DBP
653 $a Toxicity-drivers
690 $a 0485
690 $a 0768
690 $a 0573
690 $a 0595
690 $a 0383
690 $a 0388
690 $a 0528
710 2 $a University of South Carolina. $b Chemistry. $3 1020774
773 0 $t Dissertations Abstracts International $g 81-05B.
790 $a 0202
791 $a Ph.D.
792 $a 2019
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=13897837