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Biological Memories: Examining Early...

Fried, Ruby Laurel.

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Biological Memories: Examining Early Indicators of Intergenerational Health among Alaska Native Women and Children Living in Anchorage, Alaska.

Record Type:	Electronic resources : Monograph/item
Title/Author:	Biological Memories: Examining Early Indicators of Intergenerational Health among Alaska Native Women and Children Living in Anchorage, Alaska./
Author:	Fried, Ruby Laurel.
Published:	Ann Arbor : ProQuest Dissertations & Theses, : 2019,
Description:	240 p.
Notes:	Source: Dissertations Abstracts International, Volume: 81-07, Section: B.
Contained By:	Dissertations Abstracts International81-07B.
Subject:	Physical anthropology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=27544511
ISBN:	9781392353455

Biological Memories: Examining Early Indicators of Intergenerational Health among Alaska Native Women and Children Living in Anchorage, Alaska.
Fried, Ruby Laurel.

Biological Memories: Examining Early Indicators of Intergenerational Health among Alaska Native Women and Children Living in Anchorage, Alaska. - Ann Arbor : ProQuest Dissertations & Theses, 2019 - 240 p.

Source: Dissertations Abstracts International, Volume: 81-07, Section: B.

Thesis (Ph.D.)--Northwestern University, 2019.

This item must not be sold to any third party vendors.

The prevalence of obesity and associated chronic diseases has increased dramatically among the Alaska Native population within the relatively short time frame of 20-30 years. Research on dietary changes has received a great deal of attention, largely attributing these upward trends to an increasing proportion of store-bought foods relative to traditional foods. While it is clear that an individual's diet across his/her lifespan is important for his/her own health, recent research has begun to show that a person's metabolic health has origins reaching back one, to two, generations. Maternal biology and health before and during pregnancy, including body mass index and blood glucose levels, shapes a prenatal environment that may promote suboptimal fetal and infant growth patterns that increase the risk of developing obesity and metabolic dysregulation later in life.As such, with a respectful and culturally appropriate execution, this dissertation explores the potential intergenerational impacts of maternal biology and health, and early-life dietary correlates on fetal and infant growth. Research was conducted at the Alaska Native Medical Center at the Outpatient Pediatrics Clinic for a total of 16 months between October 2016 and August 2018. Survey data is from in-person interviews of 161 Alaska Native mothers who had a total of 231 children. Electronic medical record data from Southcentral Foundation on select maternal pregnancy measures, birth outcomes, and infant measures provided biological and clinical data for this study.The main findings of the study are as follows: 1) Subsistence food access, not preference, is related to subsistence food consumption during pregnancy and while living in Anchorage, 2) a greater number of sources of subsistence food consumption is significantly positively correlated with greater subsistence food consumption during pregnancy, 3) greater subsistence food consumption is significantly predictive of lower maternal pre-pregnancy body mass index (BMI) and weight, 4) lower pre-pregnancy BMI are associated with lower blood glucose levels during pregnancy as measured through Oral Glucose Tolerance Test (1-hour) and glycated hemoglobin (A1C), 5) both higher pre-pregnancy BMI and pregnancy blood glucose levels are associated with higher birth weight of newborns, 6) maternal subsistence food consumption significantly predicts child subsistence food consumption, 7) breastfeeding initiation at birth was 94% and breastfeeding through 6 months was common, and 8) breastfeeding is associated with lower weight-for-age z-scores of children between 6 months and 6 years old.By taking a lifecourse perspective to helping identify new ways to reduce obesity, diabetes, and cardiovascular disease across generations this study aligns with the visions, missions and initiatives of Southcentral Foundation, the Alaska Native Medical Center, the Alaska Native Tribal Health Consortium, and Healthy Alaskans 2020.

ISBN: 9781392353455Subjects--Topical Terms:

518358
Physical anthropology.
Subjects--Index Terms:

Alaska

Biological Memories: Examining Early Indicators of Intergenerational Health among Alaska Native Women and Children Living in Anchorage, Alaska.
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245 1 0 $a Biological Memories: Examining Early Indicators of Intergenerational Health among Alaska Native Women and Children Living in Anchorage, Alaska.
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300 $a 240 p.
500 $a Source: Dissertations Abstracts International, Volume: 81-07, Section: B.
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502 $a Thesis (Ph.D.)--Northwestern University, 2019.
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520 $a The prevalence of obesity and associated chronic diseases has increased dramatically among the Alaska Native population within the relatively short time frame of 20-30 years. Research on dietary changes has received a great deal of attention, largely attributing these upward trends to an increasing proportion of store-bought foods relative to traditional foods. While it is clear that an individual's diet across his/her lifespan is important for his/her own health, recent research has begun to show that a person's metabolic health has origins reaching back one, to two, generations. Maternal biology and health before and during pregnancy, including body mass index and blood glucose levels, shapes a prenatal environment that may promote suboptimal fetal and infant growth patterns that increase the risk of developing obesity and metabolic dysregulation later in life.As such, with a respectful and culturally appropriate execution, this dissertation explores the potential intergenerational impacts of maternal biology and health, and early-life dietary correlates on fetal and infant growth. Research was conducted at the Alaska Native Medical Center at the Outpatient Pediatrics Clinic for a total of 16 months between October 2016 and August 2018. Survey data is from in-person interviews of 161 Alaska Native mothers who had a total of 231 children. Electronic medical record data from Southcentral Foundation on select maternal pregnancy measures, birth outcomes, and infant measures provided biological and clinical data for this study.The main findings of the study are as follows: 1) Subsistence food access, not preference, is related to subsistence food consumption during pregnancy and while living in Anchorage, 2) a greater number of sources of subsistence food consumption is significantly positively correlated with greater subsistence food consumption during pregnancy, 3) greater subsistence food consumption is significantly predictive of lower maternal pre-pregnancy body mass index (BMI) and weight, 4) lower pre-pregnancy BMI are associated with lower blood glucose levels during pregnancy as measured through Oral Glucose Tolerance Test (1-hour) and glycated hemoglobin (A1C), 5) both higher pre-pregnancy BMI and pregnancy blood glucose levels are associated with higher birth weight of newborns, 6) maternal subsistence food consumption significantly predicts child subsistence food consumption, 7) breastfeeding initiation at birth was 94% and breastfeeding through 6 months was common, and 8) breastfeeding is associated with lower weight-for-age z-scores of children between 6 months and 6 years old.By taking a lifecourse perspective to helping identify new ways to reduce obesity, diabetes, and cardiovascular disease across generations this study aligns with the visions, missions and initiatives of Southcentral Foundation, the Alaska Native Medical Center, the Alaska Native Tribal Health Consortium, and Healthy Alaskans 2020.
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