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Mathematical Model for Studying Comb...

Banwarth-Kuhn, Mikahl.

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Mathematical Model for Studying Combined Effect of Individual Cell Behavior on Developing Tissue Shape in Plants.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Mathematical Model for Studying Combined Effect of Individual Cell Behavior on Developing Tissue Shape in Plants./
作者:	Banwarth-Kuhn, Mikahl.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2019,
面頁冊數:	112 p.
附註:	Source: Dissertations Abstracts International, Volume: 80-12, Section: B.
Contained By:	Dissertations Abstracts International80-12B.
標題:	Mathematics. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=13807405
ISBN:	9781392170335

Mathematical Model for Studying Combined Effect of Individual Cell Behavior on Developing Tissue Shape in Plants.
Banwarth-Kuhn, Mikahl.

Mathematical Model for Studying Combined Effect of Individual Cell Behavior on Developing Tissue Shape in Plants. - Ann Arbor : ProQuest Dissertations & Theses, 2019 - 112 p.

Source: Dissertations Abstracts International, Volume: 80-12, Section: B.

Thesis (Ph.D.)--University of California, Riverside, 2019.

This item must not be sold to any third party vendors.

The development of an organ or organism is a complex process that includes many interacting components. Scientific inquiries in developmental biology have motivated the creation of novel mathematical tools to better understand how distributions of cellular identities and phenotypes are attained through spatiotemporal regulation of cell behaviors and gene regulation. One of the central problems in animal and plant developmental biology is deciphering how chemical and mechanical signals interact within a tissue to produce organs of defined size, shape, and function. Plant development is much different from animals since the majority of organs are continually produced throughout the life of the plant and the presence of the cell wall imposes a unique constraint on cell behaviors. How exactly cell wall mechanical properties influence cell behaviors that lead to stem cell maintenance and correct organ formation is still largely unknown. To address this problem, a novel, subcellular element computational model of growth of stem cells within the multilayered shoot apical meristem (SAM) of Arabidopsis thaliana is developed and calibrated using experimental data. Novel features of the model include separate, detailed descriptions of cell wall extensibility and mechanical stiffness, deformation of the middle lamella, and increase in cytoplasmic pressure generating internal turgor pressure. The model is used to test novel hypothesized mechanisms of formation of the shape and structure of the growing, multilayered SAM based on WUS concentration of individual cells controlling cell growth rates and layer-dependent anisotropic mechanical properties of subcellular components of individual cells determining anisotropic cell expansion directions. Model simulations also provide a detailed prediction of distribution of stresses in the growing tissue which can be tested in future experiments.

ISBN: 9781392170335Subjects--Topical Terms:

515831
Mathematics.
Subjects--Index Terms:

Anisotropic cell expansion directions

Mathematical Model for Studying Combined Effect of Individual Cell Behavior on Developing Tissue Shape in Plants.
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500 $a Publisher info.: Dissertation/Thesis.
500 $a Advisor: Alber, Mark.
502 $a Thesis (Ph.D.)--University of California, Riverside, 2019.
506 $a This item must not be sold to any third party vendors.
520 $a The development of an organ or organism is a complex process that includes many interacting components. Scientific inquiries in developmental biology have motivated the creation of novel mathematical tools to better understand how distributions of cellular identities and phenotypes are attained through spatiotemporal regulation of cell behaviors and gene regulation. One of the central problems in animal and plant developmental biology is deciphering how chemical and mechanical signals interact within a tissue to produce organs of defined size, shape, and function. Plant development is much different from animals since the majority of organs are continually produced throughout the life of the plant and the presence of the cell wall imposes a unique constraint on cell behaviors. How exactly cell wall mechanical properties influence cell behaviors that lead to stem cell maintenance and correct organ formation is still largely unknown. To address this problem, a novel, subcellular element computational model of growth of stem cells within the multilayered shoot apical meristem (SAM) of Arabidopsis thaliana is developed and calibrated using experimental data. Novel features of the model include separate, detailed descriptions of cell wall extensibility and mechanical stiffness, deformation of the middle lamella, and increase in cytoplasmic pressure generating internal turgor pressure. The model is used to test novel hypothesized mechanisms of formation of the shape and structure of the growing, multilayered SAM based on WUS concentration of individual cells controlling cell growth rates and layer-dependent anisotropic mechanical properties of subcellular components of individual cells determining anisotropic cell expansion directions. Model simulations also provide a detailed prediction of distribution of stresses in the growing tissue which can be tested in future experiments.
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650 4 $a Physiology. $3 518431
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653 $a Plant development
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