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Organotypic models in drug development

Stuchi Maria-Engler, Silvya.

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Organotypic models in drug development

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Organotypic models in drug development/ edited by Monika Schafer-Korting, Silvya Stuchi Maria-Engler, Robert Landsiedel.
其他作者:	Stuchi Maria-Engler, Silvya.
出版者:	Cham :Springer International Publishing : : 2021.,
面頁冊數:	viii, 323 p. :ill. (some col.), digital ;24 cm.
內容註:	Inflammatory skin disease models in vitro and in animals - predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development "Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
Contained By:	Springer Nature eBook
標題:	Drug development. -
電子資源:	https://doi.org/10.1007/978-3-030-70063-8
ISBN:	9783030700638

Organotypic models in drug development
Organotypic models in drug development[electronic resource] /edited by Monika Schafer-Korting, Silvya Stuchi Maria-Engler, Robert Landsiedel. - Cham :Springer International Publishing :2021. - viii, 323 p. :ill. (some col.), digital ;24 cm. - Handbook of experimental pharmacology,v.2650171-2004 ;. - Handbook of experimental pharmacology ;v.265..

Inflammatory skin disease models in vitro and in animals - predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development "Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.

This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.

ISBN: 9783030700638

Standard No.: 10.1007/978-3-030-70063-8doiSubjects--Topical Terms:

716904
Drug development.

LC Class. No.: RM301.25

Dewey Class. No.: 615.19

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