東華大學圖書館 |

Language: English

Help

回圖書館首頁

手機版館藏查詢

Back

Switch To: Labeled | MARC Mode | ISBD

Design and analysis of subgroups wit...

Ting, Naitee.

Linked to FindBook

Google Book

Amazon

博客來

Design and analysis of subgroups with biopharmaceutical applications

Record Type:	Electronic resources : Monograph/item
Title/Author:	Design and analysis of subgroups with biopharmaceutical applications/ edited by Naitee Ting ... [et al.].
other author:	Ting, Naitee.
Published:	Cham :Springer International Publishing : : 2020.,
Description:	xviii, 400 p. :ill., digital ;24 cm.
[NT 15003449]:	1. Data-driven and Confirmatory Subgroup Analysis in Clinical Trials -- 2. Subgroup Analysis - A View from Industry -- 3. Biomarker-Targeted Confirmatory Trials -- 4. Considerations on Subgroup Analysis in Design and Analysis of Multi-Regional Clinical Trials -- 5. Practical Subgroup Identification Strategies in Late-stage Clinical Trials -- 6. Exploratory Subgroup Identification for Biopharmaceutical Development -- 7. Logical Inference on Treatment Efficacy When Subgroup Exists -- 8. The GUIDE Approach to Subgroup Identification and Inference -- 9. Use of the VG (Virtual Twins Combined with GUIDE) Method in the Development of Precision Medicines -- 10. Subgroups Identification for Tailored Therapies: a System of Methods, a Framework for Consistent Methodology Evaluation, and an Integrated Learn-and-confirm Approach -- 11. Developing and Validating Predictive Classifiers in Randomized Clinical Trials -- 12. Issues Related to Subgroup Analysis -- 13. Subgroup Analysis with Partial Linear Model -- 14. Subgroup Analysis in the 21st Century -- 15. Power of Statistical Tests for Subgroup Analysis in Meta-Analysis -- 16. Heterogeneity and Subgroup Analysis in Network Meta-Analysis.
Contained By:	Springer eBooks
Subject:	Drugs - Testing -
Online resource:	https://doi.org/10.1007/978-3-030-40105-4
ISBN:	9783030401054

Design and analysis of subgroups with biopharmaceutical applications
Design and analysis of subgroups with biopharmaceutical applications[electronic resource] /edited by Naitee Ting ... [et al.]. - Cham :Springer International Publishing :2020. - xviii, 400 p. :ill., digital ;24 cm. - Emerging topics in statistics and biostatistics,2524-7735. - Emerging topics in statistics and biostatistics..

1. Data-driven and Confirmatory Subgroup Analysis in Clinical Trials -- 2. Subgroup Analysis - A View from Industry -- 3. Biomarker-Targeted Confirmatory Trials -- 4. Considerations on Subgroup Analysis in Design and Analysis of Multi-Regional Clinical Trials -- 5. Practical Subgroup Identification Strategies in Late-stage Clinical Trials -- 6. Exploratory Subgroup Identification for Biopharmaceutical Development -- 7. Logical Inference on Treatment Efficacy When Subgroup Exists -- 8. The GUIDE Approach to Subgroup Identification and Inference -- 9. Use of the VG (Virtual Twins Combined with GUIDE) Method in the Development of Precision Medicines -- 10. Subgroups Identification for Tailored Therapies: a System of Methods, a Framework for Consistent Methodology Evaluation, and an Integrated Learn-and-confirm Approach -- 11. Developing and Validating Predictive Classifiers in Randomized Clinical Trials -- 12. Issues Related to Subgroup Analysis -- 13. Subgroup Analysis with Partial Linear Model -- 14. Subgroup Analysis in the 21st Century -- 15. Power of Statistical Tests for Subgroup Analysis in Meta-Analysis -- 16. Heterogeneity and Subgroup Analysis in Network Meta-Analysis.

This book provides an overview of the theories and applications on subgroups in the biopharmaceutical industry. Drawing from a range of expert perspectives in academia and industry, this collection offers an overarching dialogue about recent advances in biopharmaceutical applications, novel statistical and methodological developments, and potential future directions. The volume covers topics in subgroups in clinical trial design; subgroup identification and personalized medicine; and general issues in subgroup analyses, including regulatory ones. Included chapters present current methods, theories, and case applications in the diverse field of subgroup application and analysis. Offering timely perspectives from a range of authoritative sources, the volume is designed to have wide appeal to professionals in the pharmaceutical industry and to graduate students and researchers in academe and government.

ISBN: 9783030401054

Standard No.: 10.1007/978-3-030-40105-4doiSubjects--Topical Terms:

661379
Drugs
--Testing

LC Class. No.: RM301.27 / .D475 2020

Dewey Class. No.: 615.580724

Design and analysis of subgroups with biopharmaceutical applications
LDR:03222nmm a2200349 a 4500 001 2217916
003 DE-He213
005 20200818165732.0
006 m d
007 cr nn 008maaau
008 201120s2020 sz s 0 eng d
020 $a 9783030401054 $q (electronic bk.)
020 $a 9783030401047 $q (paper)
024 7 $a 10.1007/978-3-030-40105-4 $2 doi
035 $a 978-3-030-40105-4
040 $a GP $c GP
041 0 $a eng
050 4 $a RM301.27 $b .D475 2020
072 7 $a PBT $2 bicssc
072 7 $a MED090000 $2 bisacsh
072 7 $a PBT $2 thema
072 7 $a MBNS $2 thema
082 0 4 $a 615.580724 $2 23
090 $a RM301.27 $b .D457 2020
245 0 0 $a Design and analysis of subgroups with biopharmaceutical applications $h [electronic resource] / $c edited by Naitee Ting ... [et al.].
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2020.
300 $a xviii, 400 p. : $b ill., digital ; $c 24 cm.
490 1 $a Emerging topics in statistics and biostatistics, $x 2524-7735
505 0 $a 1. Data-driven and Confirmatory Subgroup Analysis in Clinical Trials -- 2. Subgroup Analysis - A View from Industry -- 3. Biomarker-Targeted Confirmatory Trials -- 4. Considerations on Subgroup Analysis in Design and Analysis of Multi-Regional Clinical Trials -- 5. Practical Subgroup Identification Strategies in Late-stage Clinical Trials -- 6. Exploratory Subgroup Identification for Biopharmaceutical Development -- 7. Logical Inference on Treatment Efficacy When Subgroup Exists -- 8. The GUIDE Approach to Subgroup Identification and Inference -- 9. Use of the VG (Virtual Twins Combined with GUIDE) Method in the Development of Precision Medicines -- 10. Subgroups Identification for Tailored Therapies: a System of Methods, a Framework for Consistent Methodology Evaluation, and an Integrated Learn-and-confirm Approach -- 11. Developing and Validating Predictive Classifiers in Randomized Clinical Trials -- 12. Issues Related to Subgroup Analysis -- 13. Subgroup Analysis with Partial Linear Model -- 14. Subgroup Analysis in the 21st Century -- 15. Power of Statistical Tests for Subgroup Analysis in Meta-Analysis -- 16. Heterogeneity and Subgroup Analysis in Network Meta-Analysis.
520 $a This book provides an overview of the theories and applications on subgroups in the biopharmaceutical industry. Drawing from a range of expert perspectives in academia and industry, this collection offers an overarching dialogue about recent advances in biopharmaceutical applications, novel statistical and methodological developments, and potential future directions. The volume covers topics in subgroups in clinical trial design; subgroup identification and personalized medicine; and general issues in subgroup analyses, including regulatory ones. Included chapters present current methods, theories, and case applications in the diverse field of subgroup application and analysis. Offering timely perspectives from a range of authoritative sources, the volume is designed to have wide appeal to professionals in the pharmaceutical industry and to graduate students and researchers in academe and government.
650 0 $a Drugs $x Testing $x Statistical methods. $3 661379
650 0 $a Biopharmaceutics. $3 690368
650 1 4 $a Statistics for Life Sciences, Medicine, Health Sciences. $3 891086
650 2 4 $a Biostatistics. $3 1002712
650 2 4 $a Pharmaceutical Sciences/Technology. $3 1001579
700 1 $a Ting, Naitee. $3 2184875
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a Emerging topics in statistics and biostatistics. $3 3450304
856 4 0 $u https://doi.org/10.1007/978-3-030-40105-4
950 $a Mathematics and Statistics (Springer-11649)