東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Exploration of the Independent and C...

Southmayd, Emily Anne.

FindBook

Google Book

Amazon

博客來

Exploration of the Independent and Combined Effects of Energy and Estrogen on Bone Metabolism, Bone Structure, and Estimated Bone Strength in Young Exercising Women.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Exploration of the Independent and Combined Effects of Energy and Estrogen on Bone Metabolism, Bone Structure, and Estimated Bone Strength in Young Exercising Women./
作者:	Southmayd, Emily Anne.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2019,
面頁冊數:	305 p.
附註:	Source: Dissertations Abstracts International, Volume: 80-12, Section: B.
Contained By:	Dissertations Abstracts International80-12B.
標題:	Nutrition. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=13917960
ISBN:	9781392318935

Exploration of the Independent and Combined Effects of Energy and Estrogen on Bone Metabolism, Bone Structure, and Estimated Bone Strength in Young Exercising Women.
Southmayd, Emily Anne.

Exploration of the Independent and Combined Effects of Energy and Estrogen on Bone Metabolism, Bone Structure, and Estimated Bone Strength in Young Exercising Women. - Ann Arbor : ProQuest Dissertations & Theses, 2019 - 305 p.

Source: Dissertations Abstracts International, Volume: 80-12, Section: B.

Thesis (Ph.D.)--The Pennsylvania State University, 2019.

The Female Athlete Triad (Triad), a syndrome of low energy availability, menstrual dysfunction, and low bone mineral density (BMD), affects up to 60% of exercising girls and women. As such, understanding the physiology underlying the Triad is imperative in order to identify therapeutic targets and develop effective treatment strategies to prevent long-term health detriments in afflicted women. Bone health is a major clinical outcome of concern in female athletes and exercising women with the Triad, as bone loss or suboptimal peak bone mass development may predispose women to osteoporosis and related fractures later in life. To garner a better understanding of factors contributing to bone health and to inform guidelines for treatment targets in female athletes and exercising women with the Triad, this purpose of this dissertation was 1) to assess the unique and combined effects of energy status and estrogen status on volumetric BMD (vBMD), bone geometry, and estimated bone strength in exercising women, 2) to assess the unique and combined effects of energy status and estrogen status on bone turnover in exercising women, 3) to evaluate predictors of change in bone turnover dynamics across a 12-month nutritional intervention in women with exercise-associated menstrual disturbances, and 4) to determine if bone turnover dynamics at baseline impact BMD outcomes in women with exercise-associated menstrual disturbances participating in a nutritional intervention. Key findings of the studies that made up this dissertation implicate that energy status is a main driving factor dictating vBMD, bone geometry, estimated bone strength, and bone metabolism in exercising women. The results indicate that improving energetic status will not only improve bone turnover at the cellular level, but that bone turnover favoring bone formation over bone resorption will also predict improved BMD in the following year. The findings support the guidelines put forth by the Female Athlete Triad Coalition that endorse nutritional therapy as the first line of treatment for the Triad, as low energy availability is the root cause of the clinical sequelae, including menstrual dysfunction and compromised bone health.

ISBN: 9781392318935Subjects--Topical Terms:

517777
Nutrition.

Exploration of the Independent and Combined Effects of Energy and Estrogen on Bone Metabolism, Bone Structure, and Estimated Bone Strength in Young Exercising Women.
LDR:03303nmm a2200313 4500 001 2207764
005 20190920102418.5
008 201008s2019 ||||||||||||||||| ||eng d
020 $a 9781392318935
035 $a (MiAaPQ)AAI13917960
035 $a AAI13917960
040 $a MiAaPQ $c MiAaPQ
100 1 $a Southmayd, Emily Anne. $3 3434765
245 1 0 $a Exploration of the Independent and Combined Effects of Energy and Estrogen on Bone Metabolism, Bone Structure, and Estimated Bone Strength in Young Exercising Women.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2019
300 $a 305 p.
500 $a Source: Dissertations Abstracts International, Volume: 80-12, Section: B.
500 $a Publisher info.: Dissertation/Thesis.
500 $a Advisor: Souza, Mary Jane De.
502 $a Thesis (Ph.D.)--The Pennsylvania State University, 2019.
520 $a The Female Athlete Triad (Triad), a syndrome of low energy availability, menstrual dysfunction, and low bone mineral density (BMD), affects up to 60% of exercising girls and women. As such, understanding the physiology underlying the Triad is imperative in order to identify therapeutic targets and develop effective treatment strategies to prevent long-term health detriments in afflicted women. Bone health is a major clinical outcome of concern in female athletes and exercising women with the Triad, as bone loss or suboptimal peak bone mass development may predispose women to osteoporosis and related fractures later in life. To garner a better understanding of factors contributing to bone health and to inform guidelines for treatment targets in female athletes and exercising women with the Triad, this purpose of this dissertation was 1) to assess the unique and combined effects of energy status and estrogen status on volumetric BMD (vBMD), bone geometry, and estimated bone strength in exercising women, 2) to assess the unique and combined effects of energy status and estrogen status on bone turnover in exercising women, 3) to evaluate predictors of change in bone turnover dynamics across a 12-month nutritional intervention in women with exercise-associated menstrual disturbances, and 4) to determine if bone turnover dynamics at baseline impact BMD outcomes in women with exercise-associated menstrual disturbances participating in a nutritional intervention. Key findings of the studies that made up this dissertation implicate that energy status is a main driving factor dictating vBMD, bone geometry, estimated bone strength, and bone metabolism in exercising women. The results indicate that improving energetic status will not only improve bone turnover at the cellular level, but that bone turnover favoring bone formation over bone resorption will also predict improved BMD in the following year. The findings support the guidelines put forth by the Female Athlete Triad Coalition that endorse nutritional therapy as the first line of treatment for the Triad, as low energy availability is the root cause of the clinical sequelae, including menstrual dysfunction and compromised bone health.
590 $a School code: 0176.
650 4 $a Nutrition. $3 517777
650 4 $a Kinesiology. $3 517627
650 4 $a Physiology. $3 518431
690 $a 0570
690 $a 0575
690 $a 0719
710 2 $a The Pennsylvania State University. $b Kinesiology. $3 2104413
773 0 $t Dissertations Abstracts International $g 80-12B.
790 $a 0176
791 $a Ph.D.
792 $a 2019
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=13917960