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Neurocognitive Functioning in Parkin...
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Brett, Benjamin.
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Neurocognitive Functioning in Parkinson's Disease Patients: Assessing the Unique Contributions of Depression and Fatigue while Controlling for Disease Severity.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Neurocognitive Functioning in Parkinson's Disease Patients: Assessing the Unique Contributions of Depression and Fatigue while Controlling for Disease Severity./
作者:
Brett, Benjamin.
出版者:
Ann Arbor : ProQuest Dissertations & Theses, : 2018,
面頁冊數:
29 p.
附註:
Source: Dissertation Abstracts International, Volume: 80-02(E), Section: B.
Contained By:
Dissertation Abstracts International80-02B(E).
標題:
Counseling Psychology. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10812554
ISBN:
9780438386433
Neurocognitive Functioning in Parkinson's Disease Patients: Assessing the Unique Contributions of Depression and Fatigue while Controlling for Disease Severity.
Brett, Benjamin.
Neurocognitive Functioning in Parkinson's Disease Patients: Assessing the Unique Contributions of Depression and Fatigue while Controlling for Disease Severity.
- Ann Arbor : ProQuest Dissertations & Theses, 2018 - 29 p.
Source: Dissertation Abstracts International, Volume: 80-02(E), Section: B.
Thesis (Ph.D.)--The University of Memphis, 2018.
Background: While individuals diagnosed with Parkinson's disease (PD) often experience cognitive deficits, depression, and fatigue, the relationships among these non-motor sequelae throughout the progression of the disease are unclear.
ISBN: 9780438386433Subjects--Topical Terms:
2122842
Counseling Psychology.
Neurocognitive Functioning in Parkinson's Disease Patients: Assessing the Unique Contributions of Depression and Fatigue while Controlling for Disease Severity.
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Neurocognitive Functioning in Parkinson's Disease Patients: Assessing the Unique Contributions of Depression and Fatigue while Controlling for Disease Severity.
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Source: Dissertation Abstracts International, Volume: 80-02(E), Section: B.
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Thesis (Ph.D.)--The University of Memphis, 2018.
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Background: While individuals diagnosed with Parkinson's disease (PD) often experience cognitive deficits, depression, and fatigue, the relationships among these non-motor sequelae throughout the progression of the disease are unclear.
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Objective: To examine the relationships among disease severity, depression, and fatigue and investigate the independent contributions of depression and fatigue to a composite measure of cognitive functioning, when controlling for disease severity in PD patients.
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Methods: A mixed retrospective and prospective sample of PD patients completed a comprehensive neuropsychological battery, as well as self-report measures of depression and fatigue. Cognitive functioning was represented by a summary statistic, or cognitive impairment index (CII). A hierarchal linear regression model, controlling for disease severity, examined the unique contributions of depression and fatigue on cognitive functioning. A Pearson correlation examined the relationship between depression and fatigue.
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Results: At step one, disease severity significantly contributed to the model, F(1, 41) = 48.06, p < .001, accounting for 52.8% of the variance in cognitive functioning. Introduction of depression and fatigue explained an additional 7.2% of the variance and this change in R2 was significant F(2,39) = 4.68, p < 0.05. Only depression continued to be a significant contributor beyond disease severity, t = 2.21, beta = 0.24, p < 0.05 and the change in the model was significant, F(1, 40) = 4.88, p < 0.05, R2 change = 0.05.
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Conclusions: Findings suggest that depression is uniquely associated with cognitive functioning observed in PD patients independent of disease severity or level of fatigue. Interventions targeted towards depression may improve cognitive functioning.
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