語系:
繁體中文
English
說明(常見問題)
回圖書館首頁
手機版館藏查詢
登入
回首頁
切換:
標籤
|
MARC模式
|
ISBD
Human epigenetics = how science works /
~
Carlberg, Carsten.
FindBook
Google Book
Amazon
博客來
Human epigenetics = how science works /
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Human epigenetics/ by Carsten Carlberg, Ferdinand Molnar.
其他題名:
how science works /
作者:
Carlberg, Carsten.
其他作者:
Molnar, Ferdinand.
出版者:
Cham :Springer International Publishing : : 2019.,
面頁冊數:
xvi, 153 p. :ill., digital ;24 cm.
內容註:
Introduction -- Chromatin and gene expression -- DNA methylation -- Histone modifications -- Chromatin modifying proteins and RNAs -- Embryogenesis and cellular differentiation -- Population epigenetics and aging -- Cancer epigenetics -- Neuroepigenetics -- Nutritional epigenetics -- Epigenetics of immune function -- Epigenome-environment interactions and their therapy.
Contained By:
Springer eBooks
標題:
Epigenetics. -
電子資源:
https://doi.org/10.1007/978-3-030-22907-8
ISBN:
9783030229078
Human epigenetics = how science works /
Carlberg, Carsten.
Human epigenetics
how science works /[electronic resource] :by Carsten Carlberg, Ferdinand Molnar. - Cham :Springer International Publishing :2019. - xvi, 153 p. :ill., digital ;24 cm.
Introduction -- Chromatin and gene expression -- DNA methylation -- Histone modifications -- Chromatin modifying proteins and RNAs -- Embryogenesis and cellular differentiation -- Population epigenetics and aging -- Cancer epigenetics -- Neuroepigenetics -- Nutritional epigenetics -- Epigenetics of immune function -- Epigenome-environment interactions and their therapy.
The view "It's all in our genes and we cannot change it" developed in the past 150 years since Gregor Mendel's experiments with flowering pea plants. However, there is a special form of genetics, referred to as epigenetics, which does not involve any change of our genes but regulates how and when they are used. In the cell nucleus our genes are packed into chromatin, which is a complex of histone proteins and genomic DNA, representing the molecular basis of epigenetics. Our environment and lifestyle decisions influence the epigenetics of our cells and organs, i.e. epigenetics changes dynamically throughout our whole life. Thus, we have the chance to change our epigenetics in a positive as well as negative way and are able to prevent the onset of diseases, such a type 2 diabetes or cancer. This book provides a molecular explanation how our genome is connected with environmental signals. It outlines that epigenetic programming is a learning process that results in epigenetic memory in each of the cells forming our body. The central importance of epigenetics during embryogenesis and cellular differentiation as well as in the process of aging and the risk for the development of cancer are discussed. Moreover, the role of the epigenome as a molecular storage of cellular events not only in the brain but also in metabolic organs and in the immune system is described. The book represents an updated but simplified version of our textbook "Human Epigenomics" (ISBN 978-981-10-7614-8) The first five chapters explain the molecular basis of epigenetics, while the following seven chapters provide examples for the impact of epigenetics in human health and disease.
ISBN: 9783030229078
Standard No.: 10.1007/978-3-030-22907-8doiSubjects--Topical Terms:
1568224
Epigenetics.
LC Class. No.: QH431 / .C375 2019
Dewey Class. No.: 599.935
Human epigenetics = how science works /
LDR
:03023nmm a2200325 a 4500
001
2193095
003
DE-He213
005
20191217160314.0
006
m d
007
cr nn 008maaau
008
200514s2019 gw s 0 eng d
020
$a
9783030229078
$q
(electronic bk.)
020
$a
9783030229061
$q
(paper)
024
7
$a
10.1007/978-3-030-22907-8
$2
doi
035
$a
978-3-030-22907-8
040
$a
GP
$c
GP
041
0
$a
eng
050
4
$a
QH431
$b
.C375 2019
072
7
$a
MFN
$2
bicssc
072
7
$a
MED107000
$2
bisacsh
072
7
$a
MFN
$2
thema
082
0 4
$a
599.935
$2
23
090
$a
QH431
$b
.C278 2019
100
1
$a
Carlberg, Carsten.
$3
2057498
245
1 0
$a
Human epigenetics
$h
[electronic resource] :
$b
how science works /
$c
by Carsten Carlberg, Ferdinand Molnar.
260
$a
Cham :
$b
Springer International Publishing :
$b
Imprint: Springer,
$c
2019.
300
$a
xvi, 153 p. :
$b
ill., digital ;
$c
24 cm.
505
0
$a
Introduction -- Chromatin and gene expression -- DNA methylation -- Histone modifications -- Chromatin modifying proteins and RNAs -- Embryogenesis and cellular differentiation -- Population epigenetics and aging -- Cancer epigenetics -- Neuroepigenetics -- Nutritional epigenetics -- Epigenetics of immune function -- Epigenome-environment interactions and their therapy.
520
$a
The view "It's all in our genes and we cannot change it" developed in the past 150 years since Gregor Mendel's experiments with flowering pea plants. However, there is a special form of genetics, referred to as epigenetics, which does not involve any change of our genes but regulates how and when they are used. In the cell nucleus our genes are packed into chromatin, which is a complex of histone proteins and genomic DNA, representing the molecular basis of epigenetics. Our environment and lifestyle decisions influence the epigenetics of our cells and organs, i.e. epigenetics changes dynamically throughout our whole life. Thus, we have the chance to change our epigenetics in a positive as well as negative way and are able to prevent the onset of diseases, such a type 2 diabetes or cancer. This book provides a molecular explanation how our genome is connected with environmental signals. It outlines that epigenetic programming is a learning process that results in epigenetic memory in each of the cells forming our body. The central importance of epigenetics during embryogenesis and cellular differentiation as well as in the process of aging and the risk for the development of cancer are discussed. Moreover, the role of the epigenome as a molecular storage of cellular events not only in the brain but also in metabolic organs and in the immune system is described. The book represents an updated but simplified version of our textbook "Human Epigenomics" (ISBN 978-981-10-7614-8) The first five chapters explain the molecular basis of epigenetics, while the following seven chapters provide examples for the impact of epigenetics in human health and disease.
650
0
$a
Epigenetics.
$3
1568224
650
0
$a
Human genetics.
$3
518846
650
1 4
$a
Gene Expression.
$3
600530
650
2 4
$a
Molecular Medicine.
$3
890952
650
2 4
$a
Nutrition.
$3
517777
650
2 4
$a
Cancer Research.
$3
891172
650
2 4
$a
Immunology.
$3
611031
700
1
$a
Molnar, Ferdinand.
$3
2057499
710
2
$a
SpringerLink (Online service)
$3
836513
773
0
$t
Springer eBooks
856
4 0
$u
https://doi.org/10.1007/978-3-030-22907-8
950
$a
Biomedical and Life Sciences (Springer-11642)
筆 0 讀者評論
館藏地:
全部
電子資源
出版年:
卷號:
館藏
1 筆 • 頁數 1 •
1
條碼號
典藏地名稱
館藏流通類別
資料類型
索書號
使用類型
借閱狀態
預約狀態
備註欄
附件
W9375385
電子資源
11.線上閱覽_V
電子書
EB QH431 .C375 2019
一般使用(Normal)
在架
0
1 筆 • 頁數 1 •
1
多媒體
評論
新增評論
分享你的心得
Export
取書館
處理中
...
變更密碼
登入