How to optimize fluid bed processing...
Parikh, Dilip M., (1945-)

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  • How to optimize fluid bed processing technology : = part of the expertise in pharmaceutical process technology series /
  • 紀錄類型: 書目-電子資源 : Monograph/item
    正題名/作者: How to optimize fluid bed processing technology :/ Dilip M. Parikh.
    其他題名: part of the expertise in pharmaceutical process technology series /
    作者: Parikh, Dilip M.,
    面頁冊數: 1 online resource :illustrations (some color)
    內容註: Front Cover; How to Optimize Fluid Bed Processing Technology; Copyright Page; Dedication; Contents; About the Expertise in Pharmaceutical Process Technology Series; Format; Subject Matter; Target Audience; 1 Introduction; 1.1 Introduction; 1.2 Advantages and Challenges of Fluidized Bed Granulation; 1.2.1 Granulation; 1.2.2 Drying; 1.2.3 Coating; 1.2.4 Challenges; 2 Fluidization Theory; 2.1 How Does Fluidization Take Place?; 2.2 Understanding the Particles; 2.3 Types of Fluid Beds; 2.4 Controlling Gas Velocity; 2.5 Addressing Fluidization Challenges; 2.6 Summary; References.
    內容註: 3 Fluid Bed Processor Equipment and Its Functionality3.1 Introduction; 3.2 Questions Before Specifying the Equipment; 3.2.1 Granulating in Fluid Bed; 3.2.2 Drying in Fluid Bed; 3.2.3 Coating in Fluid Bed; 3.3 Fluid Bed Processor Components; 3.3.1 Machine Tower; 3.3.2 Air Handling Unit (AHU); 3.3.3 Fan; 3.3.4 Product Container; 3.3.5 Solution Delivery System; 3.3.6 Utilities; 3.3.7 Process Filters; 3.3.8 Control Panel; 3.4 Summary; 4 Process Development; 4.1 Process Selection; 4.2 Quality by Design; 4.3 Processing in Fluid Bed; 4.3.1 Establishing the Critical Process Parameters.
    內容註: 4.4 Risk Assessment and Management4.4.1 Risk Reduction and Control; 4.5 Process Control; 4.6 Case Study; 4.7 Summary; Reference; 5 Granulation; 5.1 Theory; 5.1.1 Process; 5.2 Binders; 5.2.1 How to Select the Proper Binder?; 5.3 Nozzles; 5.3.1 The Different Orientations of the Spray Nozzle; 5.3.2 Nozzle Blockage; 5.4 Process Parameters; 5.5 Challenges in Fluid Bed Granulation; 5.6 Granulation End Point; 5.6.1 Off-Line Methods; 5.6.2 Near Infrared (NIR); 5.6.3 Focused Beam Reflectance Measurement (FBRM); 5.6.4 Spatial Filtering Velocimetry (Parsum); 5.6.5 Imaging Methods.
    內容註: 5.7 Granulation Characterization5.8 Summary; References; 6 Drying; 6.1 Theory; 6.2 Drying Granulated Product; 6.2.1 Drying Challenges; 6.2.1.1 Loading the Wet Granulated Product in the Fluid Bed Bowl; 6.2.1.2 Effect of Particle Size on Drying End Point; 6.2.1.3 Minimizing Granule Breakage; 6.2.1.4 Fluidizing Heavy/Cohesive Product; 6.2.1.5 Minimizing Product Segregation; 6.2.1.6 Avoiding Uneven Drying of the Granulation; 6.2.1.7 Drying Nonaqueous Granulation; 6.2.1.8 Minimizing the Drying Time to Increase Optimizing the Drying Process; 6.2.1.9 Increasing Yield After Drying.
    內容註: 6.2.1.10 Determination of End Point6.2.1.10.1 Off-Line Methods; 6.2.1.10.2 Other Off-Line Methods; 6.2.1.10.3 On-Line/At-Line Methods; Near-Infrared (NIR); Effusivity; 6.3 Summary; References; 7 Coating; 7.1 Introduction; 7.2 Top-Spray Coating; 7.2.1 Hot Melt Coating in Fluid Bed; 7.3 Wurster Coating; 7.3.1 Operating a Wurster Coater; 7.4 Other Coating Modules; 7.4.1 Precision Coater; 7.4.2 FlexStream System for Coating; 7.4.3 Rotary or Tangential Fluid Bed Coating; 7.5 Dry Powder Coating; 7.6 Problems in Coating in Fluid Bed; 7.7 Case Studies; 7.7.1 Case Study 1; 7.7.2 Case Study 2.
    標題: Fluidization. -
    電子資源: https://www.sciencedirect.com/science/book/9780128047279
    ISBN: 9780128047286
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