東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Asymmetric Conjugated Addition of Ca...

Eickhoff, John Adam.

FindBook

Google Book

Amazon

博客來

Asymmetric Conjugated Addition of Carboxylic Acids with Traceless Chiral Lithium Amides and Synthesis of alpha-Substituted Ketones and 2-Aminoazoles from Thioesters via Copper-Mediated Cross-Coupling.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Asymmetric Conjugated Addition of Carboxylic Acids with Traceless Chiral Lithium Amides and Synthesis of alpha-Substituted Ketones and 2-Aminoazoles from Thioesters via Copper-Mediated Cross-Coupling./
作者:	Eickhoff, John Adam.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2018,
面頁冊數:	124 p.
附註:	Source: Masters Abstracts International, Volume: 57-05.
Contained By:	Masters Abstracts International57-05(E).
標題:	Organic chemistry. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10751654
ISBN:	9780355876673

Asymmetric Conjugated Addition of Carboxylic Acids with Traceless Chiral Lithium Amides and Synthesis of alpha-Substituted Ketones and 2-Aminoazoles from Thioesters via Copper-Mediated Cross-Coupling.
Eickhoff, John Adam.

Asymmetric Conjugated Addition of Carboxylic Acids with Traceless Chiral Lithium Amides and Synthesis of alpha-Substituted Ketones and 2-Aminoazoles from Thioesters via Copper-Mediated Cross-Coupling. - Ann Arbor : ProQuest Dissertations & Theses, 2018 - 124 p.

Source: Masters Abstracts International, Volume: 57-05.

Thesis (M.S.)--University of California, Santa Barbara, 2018.

Michael addition is a premier synthetic method for carbon--carbon and carbon--heteroatom bond formation. Using chiral dilithium amides as traceless auxiliaries, we report the direct enantioselective Michael addition of carboxylic acids. A free carboxyl group in the product provides versatility for further functionalization, and the chiral reagent can be readily recovered by extraction with aqueous acid. The method has been applied in the enantioselective total synthesis of the purported structure of pulveraven B.

ISBN: 9780355876673Subjects--Topical Terms:

523952
Organic chemistry.

Asymmetric Conjugated Addition of Carboxylic Acids with Traceless Chiral Lithium Amides and Synthesis of alpha-Substituted Ketones and 2-Aminoazoles from Thioesters via Copper-Mediated Cross-Coupling.
LDR:02016nmm a2200313 4500 001 2163849
005 20181114145236.5
008 190424s2018 ||||||||||||||||| ||eng d
020 $a 9780355876673
035 $a (MiAaPQ)AAI10751654
035 $a (MiAaPQ)ucsb:13827
035 $a AAI10751654
040 $a MiAaPQ $c MiAaPQ
100 1 $a Eickhoff, John Adam. $3 3351881
245 1 0 $a Asymmetric Conjugated Addition of Carboxylic Acids with Traceless Chiral Lithium Amides and Synthesis of alpha-Substituted Ketones and 2-Aminoazoles from Thioesters via Copper-Mediated Cross-Coupling.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2018
300 $a 124 p.
500 $a Source: Masters Abstracts International, Volume: 57-05.
500 $a Includes supplementary digital materials.
500 $a Adviser: Armen Zakarian.
502 $a Thesis (M.S.)--University of California, Santa Barbara, 2018.
520 $a Michael addition is a premier synthetic method for carbon--carbon and carbon--heteroatom bond formation. Using chiral dilithium amides as traceless auxiliaries, we report the direct enantioselective Michael addition of carboxylic acids. A free carboxyl group in the product provides versatility for further functionalization, and the chiral reagent can be readily recovered by extraction with aqueous acid. The method has been applied in the enantioselective total synthesis of the purported structure of pulveraven B.
520 $a Facile synthesis of a variety of alpha-heterosubstituted ketones under mild conditions was achieved by copper-mediated cross-coupling of thioesters with functionalized organostannanes. Application of this coupling methodology provided a concise pathway for the conversion of carboxylic acids to 2-aminoimidazoles, 2-aminothiazoles, and 2-aminooxazoles via thioesters in practical yields.
590 $a School code: 0035.
650 4 $a Organic chemistry. $3 523952
690 $a 0490
710 2 $a University of California, Santa Barbara. $b Chemistry. $3 1029809
773 0 $t Masters Abstracts International $g 57-05(E).
790 $a 0035
791 $a M.S.
792 $a 2018
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10751654