東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

The Effects of Melatonin on Circadia...

Krznarich, Jennifer L.

FindBook

Google Book

Amazon

博客來

The Effects of Melatonin on Circadian and Developmental Gene Expression in Danio rerio.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The Effects of Melatonin on Circadian and Developmental Gene Expression in Danio rerio./
作者:	Krznarich, Jennifer L.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2017,
面頁冊數:	91 p.
附註:	Source: Masters Abstracts International, Volume: 57-01.
Contained By:	Masters Abstracts International57-01(E).
標題:	Developmental biology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10624240
ISBN:	9780355415896

The Effects of Melatonin on Circadian and Developmental Gene Expression in Danio rerio.
Krznarich, Jennifer L.

The Effects of Melatonin on Circadian and Developmental Gene Expression in Danio rerio. - Ann Arbor : ProQuest Dissertations & Theses, 2017 - 91 p.

Source: Masters Abstracts International, Volume: 57-01.

Thesis (M.S.)--University of Minnesota, 2017.

The circadian clock is an intracellular transcriptional-translational feedback loop that drives circadian rhythms. In zebrafish, these circadian clocks are found throughout the body and can be directly entrained by light. Melatonin synthesis begins early in zebrafish development (&sim;22 hours post fertilization) and nocturnal melatonin biosynthesis is one of the first signs of the circadian system. Our data suggest that melatonin does not play a role in establishment of daily gene expression rhythms in developing zebrafish. We found that melatonin or a melatonin receptor antagonist did not impact expression of circadian clock-controlled genes (irbp and aanat2) or genes encoding components of the circadian clock ( period3 and clock1). However, consistent with research by others suggesting that melatonin accelerates development, our preliminary work suggests that melatonin may advance gene expression onset of dbx2 and irbp in the first 24 hours of development.

ISBN: 9780355415896Subjects--Topical Terms:

592588
Developmental biology.

The Effects of Melatonin on Circadian and Developmental Gene Expression in Danio rerio.
LDR:01880nmm a2200289 4500 001 2156761
005 20180517121920.5
008 190424s2017 ||||||||||||||||| ||eng d
020 $a 9780355415896
035 $a (MiAaPQ)AAI10624240
035 $a (MiAaPQ)umn:18561
035 $a AAI10624240
040 $a MiAaPQ $c MiAaPQ
100 1 $a Krznarich, Jennifer L. $3 3344529
245 1 4 $a The Effects of Melatonin on Circadian and Developmental Gene Expression in Danio rerio.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2017
300 $a 91 p.
500 $a Source: Masters Abstracts International, Volume: 57-01.
500 $a Adviser: Jennifer Liang.
502 $a Thesis (M.S.)--University of Minnesota, 2017.
520 $a The circadian clock is an intracellular transcriptional-translational feedback loop that drives circadian rhythms. In zebrafish, these circadian clocks are found throughout the body and can be directly entrained by light. Melatonin synthesis begins early in zebrafish development (&sim;22 hours post fertilization) and nocturnal melatonin biosynthesis is one of the first signs of the circadian system. Our data suggest that melatonin does not play a role in establishment of daily gene expression rhythms in developing zebrafish. We found that melatonin or a melatonin receptor antagonist did not impact expression of circadian clock-controlled genes (irbp and aanat2) or genes encoding components of the circadian clock ( period3 and clock1). However, consistent with research by others suggesting that melatonin accelerates development, our preliminary work suggests that melatonin may advance gene expression onset of dbx2 and irbp in the first 24 hours of development.
590 $a School code: 0130.
650 4 $a Developmental biology. $3 592588
690 $a 0758
710 2 $a University of Minnesota. $b Biological Science. $3 3344530
773 0 $t Masters Abstracts International $g 57-01(E).
790 $a 0130
791 $a M.S.
792 $a 2017
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10624240