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Does Creatine Supplementation Reduce...
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Robinson, Nicholas.
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Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?/
作者:
Robinson, Nicholas.
出版者:
Ann Arbor : ProQuest Dissertations & Theses, : 2017,
面頁冊數:
92 p.
附註:
Source: Masters Abstracts International, Volume: 56-05.
Contained By:
Masters Abstracts International56-05(E).
標題:
Kinesiology. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10255141
ISBN:
9780355099478
Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?
Robinson, Nicholas.
Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?
- Ann Arbor : ProQuest Dissertations & Theses, 2017 - 92 p.
Source: Masters Abstracts International, Volume: 56-05.
Thesis (M.Sc.)--University of Toronto (Canada), 2017.
Creatine supplementation (Cr+) is known to increase recovery between exercise bouts and may increase force production capabilities of skeletal muscle. Heat shock proteins (Hsps), are up-regulated in skeletal muscle following damage, particularly following lengthening contractions (LC). Two experiments were conducted to examine the effect of Cr supplementation (Cr+; 14 days 300mg/kg) on skeletal muscle damage following 15 and 25 LCs. In each the left tibilais anterior (TA) of (n=6) Cr+ and Cr- Sprague-Dawley rats underwent LCs (either 15 or 25). No significant differences in TA Hsp content were observed between Cr- and Cr+ animals following 25 LCs, with both showing elevated Hsp72 and 25 content. Fifteen LCs also significantly increased Hsp72 content in both groups, but Hsp25 was significantly elevated only in Cr- animals. In summary, Cr supplementation did not significantly reduce LC induced muscle damage. However, it remains possible that Cr supplementation may reduce stress following 15 LCs.
ISBN: 9780355099478Subjects--Topical Terms:
517627
Kinesiology.
Does Creatine Supplementation Reduce Lengthening Contraction Induced Muscle Damage?
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Creatine supplementation (Cr+) is known to increase recovery between exercise bouts and may increase force production capabilities of skeletal muscle. Heat shock proteins (Hsps), are up-regulated in skeletal muscle following damage, particularly following lengthening contractions (LC). Two experiments were conducted to examine the effect of Cr supplementation (Cr+; 14 days 300mg/kg) on skeletal muscle damage following 15 and 25 LCs. In each the left tibilais anterior (TA) of (n=6) Cr+ and Cr- Sprague-Dawley rats underwent LCs (either 15 or 25). No significant differences in TA Hsp content were observed between Cr- and Cr+ animals following 25 LCs, with both showing elevated Hsp72 and 25 content. Fifteen LCs also significantly increased Hsp72 content in both groups, but Hsp25 was significantly elevated only in Cr- animals. In summary, Cr supplementation did not significantly reduce LC induced muscle damage. However, it remains possible that Cr supplementation may reduce stress following 15 LCs.
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