東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Design and performance of optical en...

Keenan, Maureen Molly.

FindBook

Google Book

Amazon

博客來

Design and performance of optical endoscopes for the early detection of cancer.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Design and performance of optical endoscopes for the early detection of cancer./
作者:	Keenan, Maureen Molly.
出版者:	Ann Arbor : ProQuest Dissertations & Theses, : 2016,
面頁冊數:	194 p.
附註:	Source: Dissertation Abstracts International, Volume: 78-05(E), Section: B.
Contained By:	Dissertation Abstracts International78-05B(E).
標題:	Biomedical engineering. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10172878
ISBN:	9781369276664

Design and performance of optical endoscopes for the early detection of cancer.
Keenan, Maureen Molly.

Design and performance of optical endoscopes for the early detection of cancer. - Ann Arbor : ProQuest Dissertations & Theses, 2016 - 194 p.

Source: Dissertation Abstracts International, Volume: 78-05(E), Section: B.

Thesis (Ph.D.)--The University of Arizona, 2016.

Cancer is a multistage, heterogeneous disease that develops through a series of genetic mutations. Early stage cancer is most responsive to treatment but can be the hardest to detect due to its small size, lack of definitive symptoms and potential location deep in the body. Whole body imaging methods, MRI/CT/PET, lack the necessary resolution to detect cellular level abnormalities. Optical methods, which have sufficient resolution, can be miniaturized into endoscopes, which are necessary to overcome limited penetration of light into tissue. By combining optical coherence tomography (OCT) and fluorescence imaging methods it is possible to create endoscopes sensitive to molecular and structural changes. I applied a dual-modality 2mm diameter rigid endoscope to the study of the natural history of colon cancer in a mouse model, and later applied this knowledge to the design and characterization of a 0.8 mm dual-modality flexible probe for use in human fallopian tubes. By using this endoscope, which is introduced through the natural orifice and is compatible with existing hysteroscopes, high-risk women could be screened in a procedure at a similar level of invasiveness as a colonoscopy. Therefore, the endoscope fills this gap in clinical care for women at high-risk for ovarian cancer.

ISBN: 9781369276664Subjects--Topical Terms:

535387
Biomedical engineering.

Design and performance of optical endoscopes for the early detection of cancer.
LDR:02219nmm a2200289 4500 001 2125137
005 20171113075159.5
008 180830s2016 ||||||||||||||||| ||eng d
020 $a 9781369276664
035 $a (MiAaPQ)AAI10172878
035 $a AAI10172878
040 $a MiAaPQ $c MiAaPQ
100 1 $a Keenan, Maureen Molly. $3 3287185
245 1 0 $a Design and performance of optical endoscopes for the early detection of cancer.
260 1 $a Ann Arbor : $b ProQuest Dissertations & Theses, $c 2016
300 $a 194 p.
500 $a Source: Dissertation Abstracts International, Volume: 78-05(E), Section: B.
500 $a Adviser: Jennifer K. Barton.
502 $a Thesis (Ph.D.)--The University of Arizona, 2016.
520 $a Cancer is a multistage, heterogeneous disease that develops through a series of genetic mutations. Early stage cancer is most responsive to treatment but can be the hardest to detect due to its small size, lack of definitive symptoms and potential location deep in the body. Whole body imaging methods, MRI/CT/PET, lack the necessary resolution to detect cellular level abnormalities. Optical methods, which have sufficient resolution, can be miniaturized into endoscopes, which are necessary to overcome limited penetration of light into tissue. By combining optical coherence tomography (OCT) and fluorescence imaging methods it is possible to create endoscopes sensitive to molecular and structural changes. I applied a dual-modality 2mm diameter rigid endoscope to the study of the natural history of colon cancer in a mouse model, and later applied this knowledge to the design and characterization of a 0.8 mm dual-modality flexible probe for use in human fallopian tubes. By using this endoscope, which is introduced through the natural orifice and is compatible with existing hysteroscopes, high-risk women could be screened in a procedure at a similar level of invasiveness as a colonoscopy. Therefore, the endoscope fills this gap in clinical care for women at high-risk for ovarian cancer.
590 $a School code: 0009.
650 4 $a Biomedical engineering. $3 535387
650 4 $a Optics. $3 517925
690 $a 0541
690 $a 0752
710 2 $a The University of Arizona. $b Biomedical Engineering. $3 2092025
773 0 $t Dissertation Abstracts International $g 78-05B(E).
790 $a 0009
791 $a Ph.D.
792 $a 2016
793 $a English
856 4 0 $u http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10172878