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Does genotype moderate the effects o...

Varangis, Eleanna Martha Lyman.

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Does genotype moderate the effects of concussion history and contact exposure on working memory processes in retired football players?

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Does genotype moderate the effects of concussion history and contact exposure on working memory processes in retired football players?/
作者:	Varangis, Eleanna Martha Lyman.
面頁冊數:	86 p.
附註:	Source: Masters Abstracts International, Volume: 54-05.
Contained By:	Masters Abstracts International54-05(E).
標題:	Cognitive psychology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1589131
ISBN:	9781321761139

Does genotype moderate the effects of concussion history and contact exposure on working memory processes in retired football players?
Varangis, Eleanna Martha Lyman.

Does genotype moderate the effects of concussion history and contact exposure on working memory processes in retired football players? - 86 p.

Source: Masters Abstracts International, Volume: 54-05.

Thesis (M.A.)--The University of North Carolina at Chapel Hill, 2015.

Recent studies have linked concussions earlier in life and later memory problems, but little is known about neurocognitive long-term effects of concussion, and whether a genetic risk factor for Alzheimer's Disease, Apolipoprotein-e4 (APOE-e4), might play a role in these long-term effects. In the present study, participants between 50-65 (N=63) were grouped based on concussion history (0-1 or 3+), football exposure (college or college+NFL), and APOE-e4 status (APOE-e4+ or APOE-e4-). Participants completed two batteries of neurocognitive tasks, and performed an fMRI-adapted N-back task. Neurocognitive results revealed selective deficits in memory across all sub-groups, but no differences between the groups. Functional connectivity results suggested that APOE-e4 genotype interacted with concussion and exposure history in accounting for differences in connectivity within a fronto-parietal working memory network. Thus, while there are no behavioral differences between groups, functional connectivity may be altered by the interaction between concussion history, football exposure, and APOE-e4 status.

ISBN: 9781321761139Subjects--Topical Terms:

523881
Cognitive psychology.

Does genotype moderate the effects of concussion history and contact exposure on working memory processes in retired football players?
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