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Incidence of and Risk Factors for Th...
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Kobayashi, Monica Gaines.
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Incidence of and Risk Factors for Thromboembolic Events in Elderly Medicare Patients With Kidney Cancer.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
Incidence of and Risk Factors for Thromboembolic Events in Elderly Medicare Patients With Kidney Cancer./
作者:
Kobayashi, Monica Gaines.
面頁冊數:
286 p.
附註:
Source: Dissertation Abstracts International, Volume: 77-12(E), Section: B.
Contained By:
Dissertation Abstracts International77-12B(E).
標題:
Public health. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=10134920
ISBN:
9781339928531
Incidence of and Risk Factors for Thromboembolic Events in Elderly Medicare Patients With Kidney Cancer.
Kobayashi, Monica Gaines.
Incidence of and Risk Factors for Thromboembolic Events in Elderly Medicare Patients With Kidney Cancer.
- 286 p.
Source: Dissertation Abstracts International, Volume: 77-12(E), Section: B.
Thesis (D.P.H.)--Walden University, 2016.
The incidence of venous and arterial thromboembolic events (VTEs/ATEs) varies greatly by cancer type and age, with increased risk in the elderly. Very little research has been reported specific to elderly kidney cancer patients. Retrospective cohort analyses of Medicare patients, 11,463 with and 11,463 without kidney cancer, between 2003 and 2010 were conducted to compare incidence rates of VTEs/ATEs in cancer patients with matched noncancer patients and to assess independent risk factors for VTEs in cancer patients. The advanced epidemiology triangle was the theoretical framework used to interpret the association between incident events and other factors. Using Cox proportional hazard regression, the first 2 research questions examined whether the incidence rates of VTEs/ATEs were higher in kidney cancer patients than noncancer patients; the third research question assessed which factors were associated with VTEs after kidney cancer diagnosis. In the year prior to index date, cancer patients had higher incidence rates of VTEs than noncancer patients; the incidence rate of myocardial infarction was higher in cancer patients than noncancer patients for patients with a history of cardiovascular disease. Elderly kidney cancer patients with transitional cell tumors had lower rates of pulmonary embolism and ischemic stroke compared to patients with clear cell tumors. Recent history of VTE and Charlson comorbidity score were strong predictors of VTE after cancer diagnosis. These results can lead to positive social change by helping healthcare providers to determine who may benefit from closer observation or prophylaxis to prevent or minimize morbidity from these thromboembolic events, thus improving health and quality of life for elderly kidney cancer patients.
ISBN: 9781339928531Subjects--Topical Terms:
534748
Public health.
Incidence of and Risk Factors for Thromboembolic Events in Elderly Medicare Patients With Kidney Cancer.
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The incidence of venous and arterial thromboembolic events (VTEs/ATEs) varies greatly by cancer type and age, with increased risk in the elderly. Very little research has been reported specific to elderly kidney cancer patients. Retrospective cohort analyses of Medicare patients, 11,463 with and 11,463 without kidney cancer, between 2003 and 2010 were conducted to compare incidence rates of VTEs/ATEs in cancer patients with matched noncancer patients and to assess independent risk factors for VTEs in cancer patients. The advanced epidemiology triangle was the theoretical framework used to interpret the association between incident events and other factors. Using Cox proportional hazard regression, the first 2 research questions examined whether the incidence rates of VTEs/ATEs were higher in kidney cancer patients than noncancer patients; the third research question assessed which factors were associated with VTEs after kidney cancer diagnosis. In the year prior to index date, cancer patients had higher incidence rates of VTEs than noncancer patients; the incidence rate of myocardial infarction was higher in cancer patients than noncancer patients for patients with a history of cardiovascular disease. Elderly kidney cancer patients with transitional cell tumors had lower rates of pulmonary embolism and ischemic stroke compared to patients with clear cell tumors. Recent history of VTE and Charlson comorbidity score were strong predictors of VTE after cancer diagnosis. These results can lead to positive social change by helping healthcare providers to determine who may benefit from closer observation or prophylaxis to prevent or minimize morbidity from these thromboembolic events, thus improving health and quality of life for elderly kidney cancer patients.
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