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While they wait: Rodent frontal cort...
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Narayanan, Nandakumar.
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While they wait: Rodent frontal cortex and delayed response performance.
紀錄類型:
書目-電子資源 : Monograph/item
正題名/作者:
While they wait: Rodent frontal cortex and delayed response performance./
作者:
Narayanan, Nandakumar.
面頁冊數:
129 p.
附註:
Source: Dissertation Abstracts International, Volume: 69-06, Section: B, page: 3434.
Contained By:
Dissertation Abstracts International69-06B.
標題:
Neurosciences. -
電子資源:
http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=3317182
ISBN:
9780549658238
While they wait: Rodent frontal cortex and delayed response performance.
Narayanan, Nandakumar.
While they wait: Rodent frontal cortex and delayed response performance.
- 129 p.
Source: Dissertation Abstracts International, Volume: 69-06, Section: B, page: 3434.
Thesis (Ph.D.)--Yale University, 2008.
Waiting requires suppressing responses until the right time or the right stimulus has occurred. Here, we describe a neural system in rats that controls waiting during a delayed response task. First, we show that inactivating rodent prefrontal cortex impairs rodents' ability to wait in tasks with variable and fixed delays. We then record from populations of neurons from rodent frontal cortex and demonstrate that rodent prefrontal regions are involved in anticipating the expected timing of forthcoming trigger stimuli. Finally, we show that inactivating rodent prefrontal cortex specifically decreases delay-related neural activity in rodent motor cortex. These data are convergent with primate studies that suggest that prefrontal regions are critical to the temporal organization of behavior, and provide strong evidence that in rats, prefrontal regions are critical to the temporal control of action.
ISBN: 9780549658238Subjects--Topical Terms:
588700
Neurosciences.
While they wait: Rodent frontal cortex and delayed response performance.
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Waiting requires suppressing responses until the right time or the right stimulus has occurred. Here, we describe a neural system in rats that controls waiting during a delayed response task. First, we show that inactivating rodent prefrontal cortex impairs rodents' ability to wait in tasks with variable and fixed delays. We then record from populations of neurons from rodent frontal cortex and demonstrate that rodent prefrontal regions are involved in anticipating the expected timing of forthcoming trigger stimuli. Finally, we show that inactivating rodent prefrontal cortex specifically decreases delay-related neural activity in rodent motor cortex. These data are convergent with primate studies that suggest that prefrontal regions are critical to the temporal organization of behavior, and provide strong evidence that in rats, prefrontal regions are critical to the temporal control of action.
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