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Using laser correlation spectroscopy...

Al Ogaidi, Marwah Ali Zaidan.

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Using laser correlation spectroscopy to study gold nanoparticles diffusion dynamics for photodynamic therapy.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Using laser correlation spectroscopy to study gold nanoparticles diffusion dynamics for photodynamic therapy./
作者:	Al Ogaidi, Marwah Ali Zaidan.
面頁冊數:	56 p.
附註:	Source: Masters Abstracts International, Volume: 55-03.
Contained By:	Masters Abstracts International55-03(E).
標題:	Electrical engineering. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1605245
ISBN:	9781339316376

Using laser correlation spectroscopy to study gold nanoparticles diffusion dynamics for photodynamic therapy.
Al Ogaidi, Marwah Ali Zaidan.

Using laser correlation spectroscopy to study gold nanoparticles diffusion dynamics for photodynamic therapy. - 56 p.

Source: Masters Abstracts International, Volume: 55-03.

Thesis (M.S.)--University of Colorado at Denver, 2015.

The dynamic behaviour of gold nanoparticles of different shapes (sphere and rod) were studied under different experimental conditions to be used for drug delivery in photodynamic therapy. Fluorescence correlation spectroscopy (FCS) using single photon excitation had been used to study the diffusion dynamics of gold nanoparticles of different shapes in water solution to utilize these results for further enhancement for the photodynamic therapy. We analyzed four different colloidal gold solutions (colloidal gold nanosphere solution, colloidal gold nanosphere-photosensitizer solution, colloidal gold nanoshpere- Rhodamine B solution, and colloidal gold nanorods-Rhodamine B solution) using the custom software (MAZ-2015) we made to analyze the results for these samples by calculating and fitting the autocorrelation. We found that we could get a reliable correlation when laser power was higher than 4.2 microW. The phosphate buffered saline shows the best results over the nanopure water and culture media when used to dilute the colloidal gold nanoparticles solutions, and the (MAZ-2015) software provides a comparable results to commercial software provided by the microscope vendors. The results indicated that gold nanosphere conjugated with Rhodamine-B can be a potential candidate to study drug transport to cells in photodynamic therapy treatment.

ISBN: 9781339316376Subjects--Topical Terms:

649834
Electrical engineering.

Using laser correlation spectroscopy to study gold nanoparticles diffusion dynamics for photodynamic therapy.
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300 $a 56 p.
500 $a Source: Masters Abstracts International, Volume: 55-03.
500 $a Adviser: Tim C. Lei.
502 $a Thesis (M.S.)--University of Colorado at Denver, 2015.
520 $a The dynamic behaviour of gold nanoparticles of different shapes (sphere and rod) were studied under different experimental conditions to be used for drug delivery in photodynamic therapy. Fluorescence correlation spectroscopy (FCS) using single photon excitation had been used to study the diffusion dynamics of gold nanoparticles of different shapes in water solution to utilize these results for further enhancement for the photodynamic therapy. We analyzed four different colloidal gold solutions (colloidal gold nanosphere solution, colloidal gold nanosphere-photosensitizer solution, colloidal gold nanoshpere- Rhodamine B solution, and colloidal gold nanorods-Rhodamine B solution) using the custom software (MAZ-2015) we made to analyze the results for these samples by calculating and fitting the autocorrelation. We found that we could get a reliable correlation when laser power was higher than 4.2 microW. The phosphate buffered saline shows the best results over the nanopure water and culture media when used to dilute the colloidal gold nanoparticles solutions, and the (MAZ-2015) software provides a comparable results to commercial software provided by the microscope vendors. The results indicated that gold nanosphere conjugated with Rhodamine-B can be a potential candidate to study drug transport to cells in photodynamic therapy treatment.
520 $a The form and content of this abstract is approved. I recommend its publication. Approved: Approved: Tim C. Lei.
590 $a School code: 0765.
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