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The impact of primary motor cortex, ...

Olix, Daniel James.

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The impact of primary motor cortex, spinal cord, and sciatic nerve cooling on spinal reflex activity in the rat: A reversible deactivation study.

Record Type:	Electronic resources : Monograph/item
Title/Author:	The impact of primary motor cortex, spinal cord, and sciatic nerve cooling on spinal reflex activity in the rat: A reversible deactivation study./
Author:	Olix, Daniel James.
Description:	56 p.
Notes:	Source: Masters Abstracts International, Volume: 54-05.
Contained By:	Masters Abstracts International54-05(E).
Subject:	Physiology. -
Online resource:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1591807
ISBN:	9781321837766

The impact of primary motor cortex, spinal cord, and sciatic nerve cooling on spinal reflex activity in the rat: A reversible deactivation study.
Olix, Daniel James.

The impact of primary motor cortex, spinal cord, and sciatic nerve cooling on spinal reflex activity in the rat: A reversible deactivation study. - 56 p.

Source: Masters Abstracts International, Volume: 54-05.

Thesis (M.S.)--Boston University, 2015.

This item must not be sold to any third party vendors.

The influence of spinal reflex arcs on lower limb movement cannot be understated, but the individual contribution of various parts of the reflex pathway, namely the primary motor cortex, spinal cord, and sciatic nerve, are incompletely known. This study aims to consider each of these to develop a better understanding of how spinal cord reflexes and the relationship between the central and peripheral nervous systems, particularly in terms of motor control. In the anesthetized rat, recording electrodes were placed in the tibialis anterior muscle of the hindlimb to record both the direct muscle response (M-wave) and the muscle reflex response (H-wave) in response to electrical stimulation of the sciatic nerve. After baseline recordings, thermal deactivation was used to selectively silence the primary motor cortex, spinal cord, or sciatic nerve in the rat and test the hypothesis that different locations exerted different effects on the excitability and timing of the spinal cord reflexes. Deactivation of motor cortex produced a faster or more excitable spinal cord reflex, whereas sciatic nerve deactivation produced a profound attenuation of both the M and the H waves. This study strongly supports the contention that the motor cortex, through pathways that travel through the spinal cord, normally serves to inhibit the excitability of spinal cord reflexes.

ISBN: 9781321837766Subjects--Topical Terms:

518431
Physiology.

The impact of primary motor cortex, spinal cord, and sciatic nerve cooling on spinal reflex activity in the rat: A reversible deactivation study.
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100 1 $a Olix, Daniel James. $3 3181249
245 1 4 $a The impact of primary motor cortex, spinal cord, and sciatic nerve cooling on spinal reflex activity in the rat: A reversible deactivation study.
300 $a 56 p.
500 $a Source: Masters Abstracts International, Volume: 54-05.
500 $a Advisers: R. Jarrett Rushmore; Theresa A. Davies.
502 $a Thesis (M.S.)--Boston University, 2015.
506 $a This item must not be sold to any third party vendors.
520 $a The influence of spinal reflex arcs on lower limb movement cannot be understated, but the individual contribution of various parts of the reflex pathway, namely the primary motor cortex, spinal cord, and sciatic nerve, are incompletely known. This study aims to consider each of these to develop a better understanding of how spinal cord reflexes and the relationship between the central and peripheral nervous systems, particularly in terms of motor control. In the anesthetized rat, recording electrodes were placed in the tibialis anterior muscle of the hindlimb to record both the direct muscle response (M-wave) and the muscle reflex response (H-wave) in response to electrical stimulation of the sciatic nerve. After baseline recordings, thermal deactivation was used to selectively silence the primary motor cortex, spinal cord, or sciatic nerve in the rat and test the hypothesis that different locations exerted different effects on the excitability and timing of the spinal cord reflexes. Deactivation of motor cortex produced a faster or more excitable spinal cord reflex, whereas sciatic nerve deactivation produced a profound attenuation of both the M and the H waves. This study strongly supports the contention that the motor cortex, through pathways that travel through the spinal cord, normally serves to inhibit the excitability of spinal cord reflexes.
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