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The effects of Type 1 Diabetes Melli...

Carter, Michael R.

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The effects of Type 1 Diabetes Mellitus on Heat Loss during Exercise in the Heat.

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	The effects of Type 1 Diabetes Mellitus on Heat Loss during Exercise in the Heat./
作者:	Carter, Michael R.
面頁冊數:	85 p.
附註:	Source: Masters Abstracts International, Volume: 52-06.
Contained By:	Masters Abstracts International52-06(E).
標題:	Health Sciences, Pathology. -
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=MS26724
ISBN:	9780499267245

The effects of Type 1 Diabetes Mellitus on Heat Loss during Exercise in the Heat.
Carter, Michael R.

The effects of Type 1 Diabetes Mellitus on Heat Loss during Exercise in the Heat. - 85 p.

Source: Masters Abstracts International, Volume: 52-06.

Thesis (M.Sc.)--University of Ottawa (Canada), 2014.

Studies show that vasomotor and sudomotor activity is compromised in individuals with type 1 Diabetes (T1DM) which could lead to altered thermoregulatory function. However, recent work suggests that the impairments may only be evidenced beyond a certain level of heat stress. We therefore examined T1DM-related differences in heat loss responses of sweating and skin blood flow (SkBF) during exercise performed at progressive increases in the requirement for heat loss. Participants were matched for age, sex, body surface area and fitness cycled at fixed rates of metabolic heat production of 200, 250, and 300 W&dot;m -2 of body surface area, each rate being performed sequentially for 30 min. Local sweat rate (LSR), sweat gland activation (SGA), and sweat gland output (SGO) were measured on the upper back, chest and forearm while SkBF (laser-Doppler) was measured on the forearm and upper back only.

ISBN: 9780499267245Subjects--Topical Terms:

1017854
Health Sciences, Pathology.

The effects of Type 1 Diabetes Mellitus on Heat Loss during Exercise in the Heat.
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502 $a Thesis (M.Sc.)--University of Ottawa (Canada), 2014.
520 $a Studies show that vasomotor and sudomotor activity is compromised in individuals with type 1 Diabetes (T1DM) which could lead to altered thermoregulatory function. However, recent work suggests that the impairments may only be evidenced beyond a certain level of heat stress. We therefore examined T1DM-related differences in heat loss responses of sweating and skin blood flow (SkBF) during exercise performed at progressive increases in the requirement for heat loss. Participants were matched for age, sex, body surface area and fitness cycled at fixed rates of metabolic heat production of 200, 250, and 300 W&dot;m -2 of body surface area, each rate being performed sequentially for 30 min. Local sweat rate (LSR), sweat gland activation (SGA), and sweat gland output (SGO) were measured on the upper back, chest and forearm while SkBF (laser-Doppler) was measured on the forearm and upper back only.
520 $a We found that despite a similar requirement for heat loss, LSR was lower in T1DM on the chest and forearm only, relative to Control and only different at the end of the second and third exercise period. Differences in chest LSR were due to reduced SGA whereas the decreased forearm LSR was the result of a decrease in SGO. SkBF did not differ between groups. The reduction in the sweating response in the T1DM group was paralleled by a greater increase in core temperature. We show that T1DM impairs heat dissipation as evidenced by reductions in LSR and not SkBF. A compromised thermoregulatory response during and following physical exertion is of considerable concern due to the associated increased risk of post-exertion heat-related injury.
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