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Copper-catalyzed electrophilic amina...

McDonald, Stacey L.

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Copper-catalyzed electrophilic amination of sp2 and sp3 C-H bonds

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Copper-catalyzed electrophilic amination of sp2 and sp3 C-H bonds/ by Stacey L. McDonald.
作者:	McDonald, Stacey L.
出版者:	Cham :Springer International Publishing : : 2016.,
面頁冊數:	xxiii, 144 p. :ill., digital ;24 cm.
Contained By:	Springer eBooks
標題:	Amination. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-38878-6
ISBN:	9783319388786

Copper-catalyzed electrophilic amination of sp2 and sp3 C-H bonds
McDonald, Stacey L.

Copper-catalyzed electrophilic amination of sp2 and sp3 C-H bonds[electronic resource] /by Stacey L. McDonald. - Cham :Springer International Publishing :2016. - xxiii, 144 p. :ill., digital ;24 cm. - Springer theses,2190-5053. - Springer theses..

This thesis reports the latest developments in the direct amination of various C−H bonds using an H−Zn exchange/electrophilic amination strategy. McDonald and co-workers reveal this approach to be a rapid and powerful method for accessing a variety of functionalized amines. The material outlined in this book shows how McDonald achieved C−H zincation using strong, non-nucleophilic zinc bases and subsequent electrophilic amination of the corresponding zinc carbanions with copper as a catalyst and O-benzoylhydroxylamines as the electrophilic nitrogen source. McDonald's findings are of relevance to medicinal chemistry, drug discovery and materials science. Her thesis is a source of inspiration for scientists entering the field and students beginning their PhD in a related area.

ISBN: 9783319388786

Standard No.: 10.1007/978-3-319-38878-6doiSubjects--Topical Terms:

2059185
Amination.

LC Class. No.: QD281.A6

Dewey Class. No.: 547.27

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