東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Therapeutic potentials of curcumin f...

Farooqui, Akhlaq A.

FindBook

Google Book

Amazon

博客來

Therapeutic potentials of curcumin for Alzheimer disease

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Therapeutic potentials of curcumin for Alzheimer disease/ by Akhlaq A. Farooqui.
作者:	Farooqui, Akhlaq A.
出版者:	Cham :Springer International Publishing : : 2016.,
面頁冊數:	xix, 402 p. :ill., digital ;24 cm.
內容註:	Preface -- Effect of long term consumption of high calorie diet and calorie restriction on human health -- Neurochemical effects of long term consumption of high fat diet -- Neurochemical effects of long term consumption of simple carbohydrates -- Effects of long term consumption of animal proteins in the high calorie diet -- Effect of soft drink consumption on human health -- Contribution of salt in inducing biochemical changes in the brain -- Importance and roles of fiber in the diet -- Effects of the high calorie diet on the development of chronic visceral disease -- Effects of long term consumption of high calorie diet on neurological disorders -- Perspective and direction for future research: modification of high calorie diet needed for optimal health of human visceral and brain tissues -- Index.
Contained By:	Springer eBooks
標題:	Turmeric - Therapeutic use. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-15889-1
ISBN:	9783319158891

Therapeutic potentials of curcumin for Alzheimer disease
Farooqui, Akhlaq A.

Therapeutic potentials of curcumin for Alzheimer disease[electronic resource] /by Akhlaq A. Farooqui. - Cham :Springer International Publishing :2016. - xix, 402 p. :ill., digital ;24 cm.

Preface -- Effect of long term consumption of high calorie diet and calorie restriction on human health -- Neurochemical effects of long term consumption of high fat diet -- Neurochemical effects of long term consumption of simple carbohydrates -- Effects of long term consumption of animal proteins in the high calorie diet -- Effect of soft drink consumption on human health -- Contribution of salt in inducing biochemical changes in the brain -- Importance and roles of fiber in the diet -- Effects of the high calorie diet on the development of chronic visceral disease -- Effects of long term consumption of high calorie diet on neurological disorders -- Perspective and direction for future research: modification of high calorie diet needed for optimal health of human visceral and brain tissues -- Index.

Curcumin is a yellow-orange pigment obtained from the plant Curcuma longa. The powdered rhizome of this plant, called turmeric, is a common ingredient in curry powders and has a long history of use in traditional Asian medicine. Thus, curcumin has been used extensively in Ayurvedic medicine (Indian system of medicine) and Chinese traditional medicine for centuries as a antinociceptive, antiinflammatory, and antishock agent to relieve pain and inflammation. Epidemiological studies have revealed that in India, where dietary curcumin is consumed daily in the form of curry than in the United States, the morbidity rate attributed to Alzheimer disease (AD) for Indian elders (70-79 years old) is 4.4 times lower compared to the same age group of Americans. Furthermore, elderly healthy individuals who consume curry more frequently show better cognitive performance than senior who do not consume curry. Curcumin has been extensively investigated for treating AD over decades in animal model of AD, where curcumin crosses blood brain barrier and neural cell membranes and mediates its antioxidant, antiinflammatory, antiamyloidogenic , antiangiogenic, antiproliferative, antiapoptotic, metal chelating effects leading to retardation of signal transduction pathways associated with oxidative stress and neuroinflammation. Thus, curcumin fulfills the characteristics for an ideal neuroprotective agent for AD with its low toxicity, affordability, and easy accessibility. However, poor bioavailability of curcumin is the major hurdle for its more widespread use in animals and humans. The bioavailability of curcumin can be increased by encapsulation of curcumin into liposomes, cyclodextrin, curcumin conjugate with PLGA, complexation with phospholipids, and synthesis of curcumin analogs. This monograph is the first to describe neurochemical potentials of curcumin for the treatment of AD. This monograph presents readers with cutting edge and comprehensive information on the effect of curcumin on visceral organs and brain. It is hoped that this monograph will be useful to postgraduate students, faculty, research scientists, nutritionists, and physicians, who are curious signal transduction processes associated with antioxidant, antiinflammatory, antiamyloidogenic , antiangiogenic, antiproliferative, and antiapoptotic effects of curcumin on the brain.

ISBN: 9783319158891

Standard No.: 10.1007/978-3-319-15889-1doiSubjects--Topical Terms:

2046205
Turmeric
--Therapeutic use.

LC Class. No.: RM666.T88

Dewey Class. No.: 615.321

Therapeutic potentials of curcumin for Alzheimer disease
LDR:04120nmm m2200313 m 4500 001 2032373
003 DE-He213
005 20160908154810.0
006 m d
007 cr nn 008maaau
008 161011s2016 gw s 0 eng d
020 $a 9783319158891 $q (electronic bk.)
020 $a 9783319158884 $q (paper)
024 7 $a 10.1007/978-3-319-15889-1 $2 doi
035 $a 978-3-319-15889-1
040 $a GP $c GP
041 0 $a eng
050 4 $a RM666.T88
072 7 $a MJN $2 bicssc
072 7 $a MED057000 $2 bisacsh
082 0 4 $a 615.321 $2 23
090 $a RM666.T88 $b F237 2016
100 1 $a Farooqui, Akhlaq A. $3 898724
245 1 0 $a Therapeutic potentials of curcumin for Alzheimer disease $h [electronic resource] / $c by Akhlaq A. Farooqui.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a xix, 402 p. : $b ill., digital ; $c 24 cm.
505 0 $a Preface -- Effect of long term consumption of high calorie diet and calorie restriction on human health -- Neurochemical effects of long term consumption of high fat diet -- Neurochemical effects of long term consumption of simple carbohydrates -- Effects of long term consumption of animal proteins in the high calorie diet -- Effect of soft drink consumption on human health -- Contribution of salt in inducing biochemical changes in the brain -- Importance and roles of fiber in the diet -- Effects of the high calorie diet on the development of chronic visceral disease -- Effects of long term consumption of high calorie diet on neurological disorders -- Perspective and direction for future research: modification of high calorie diet needed for optimal health of human visceral and brain tissues -- Index.
520 $a Curcumin is a yellow-orange pigment obtained from the plant Curcuma longa. The powdered rhizome of this plant, called turmeric, is a common ingredient in curry powders and has a long history of use in traditional Asian medicine. Thus, curcumin has been used extensively in Ayurvedic medicine (Indian system of medicine) and Chinese traditional medicine for centuries as a antinociceptive, antiinflammatory, and antishock agent to relieve pain and inflammation. Epidemiological studies have revealed that in India, where dietary curcumin is consumed daily in the form of curry than in the United States, the morbidity rate attributed to Alzheimer disease (AD) for Indian elders (70-79 years old) is 4.4 times lower compared to the same age group of Americans. Furthermore, elderly healthy individuals who consume curry more frequently show better cognitive performance than senior who do not consume curry. Curcumin has been extensively investigated for treating AD over decades in animal model of AD, where curcumin crosses blood brain barrier and neural cell membranes and mediates its antioxidant, antiinflammatory, antiamyloidogenic , antiangiogenic, antiproliferative, antiapoptotic, metal chelating effects leading to retardation of signal transduction pathways associated with oxidative stress and neuroinflammation. Thus, curcumin fulfills the characteristics for an ideal neuroprotective agent for AD with its low toxicity, affordability, and easy accessibility. However, poor bioavailability of curcumin is the major hurdle for its more widespread use in animals and humans. The bioavailability of curcumin can be increased by encapsulation of curcumin into liposomes, cyclodextrin, curcumin conjugate with PLGA, complexation with phospholipids, and synthesis of curcumin analogs. This monograph is the first to describe neurochemical potentials of curcumin for the treatment of AD. This monograph presents readers with cutting edge and comprehensive information on the effect of curcumin on visceral organs and brain. It is hoped that this monograph will be useful to postgraduate students, faculty, research scientists, nutritionists, and physicians, who are curious signal transduction processes associated with antioxidant, antiinflammatory, antiamyloidogenic , antiangiogenic, antiproliferative, and antiapoptotic effects of curcumin on the brain.
650 0 $a Turmeric $x Therapeutic use. $3 2046205
650 0 $a Alzheimer's disease $x Diet therapy. $3 2186351
650 0 $a Phytochemicals $x Therapeutic use. $3 1619649
650 0 $a Plant polyphenols $x Therapeutic use. $3 2186352
650 1 4 $a Biomedicine. $3 890831
650 2 4 $a Neurochemistry. $3 657592
650 2 4 $a Food Science. $3 890841
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-15889-1
950 $a Biomedical and Life Sciences (Springer-11642)