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Systemic sclerosis

Takehara, Kazuhiko.

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Systemic sclerosis

Record Type:	Electronic resources : Monograph/item
Title/Author:	Systemic sclerosis/ edited by Kazuhiko Takehara, Manabu Fujimoto, Masataka Kuwana.
other author:	Takehara, Kazuhiko.
Published:	Tokyo :Springer Japan : : 2016.,
Description:	viii, 247 p. :ill., digital ;24 cm.
[NT 15003449]:	1 -- Fibrosis: overview 2 -- Autoimmunity in systemic sclerosis: Overview 3 -- Endothelial progenitor cell 4 -- Animal models of systemic sclerosis 5 -- Genetics of Systemic Sclerosis 6 -- Role of the Interleukin-1 Family in the Fibrogenic Phenotype in Systemic Sclerosis 7 -- Interleukin-6 in the Pathogenesis of Systemic Sclerosis 8 -- Epigenetics 9 -- Transforming Growth Factor-ß and Connective Tissue Growth Factor 10 -- Endothelin 11 -- The Role of B cells in Systemic Sclerosis 12 -- Fli1 13 -- Biomarker 14 -- Autoantibodies in Systemic Sclerosis.
Contained By:	Springer eBooks
Subject:	Systemic scleroderma. -
Online resource:	http://dx.doi.org/10.1007/978-4-431-55708-1
ISBN:	9784431557081$q(electronic bk.)

Systemic sclerosis
Systemic sclerosis[electronic resource] /edited by Kazuhiko Takehara, Manabu Fujimoto, Masataka Kuwana. - Tokyo :Springer Japan :2016. - viii, 247 p. :ill., digital ;24 cm.

1 -- Fibrosis: overview 2 -- Autoimmunity in systemic sclerosis: Overview 3 -- Endothelial progenitor cell 4 -- Animal models of systemic sclerosis 5 -- Genetics of Systemic Sclerosis 6 -- Role of the Interleukin-1 Family in the Fibrogenic Phenotype in Systemic Sclerosis 7 -- Interleukin-6 in the Pathogenesis of Systemic Sclerosis 8 -- Epigenetics 9 -- Transforming Growth Factor-ß and Connective Tissue Growth Factor 10 -- Endothelin 11 -- The Role of B cells in Systemic Sclerosis 12 -- Fli1 13 -- Biomarker 14 -- Autoantibodies in Systemic Sclerosis.

This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma) Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists.

ISBN: 9784431557081$q(electronic bk.)

Standard No.: 10.1007/978-4-431-55708-1doiSubjects--Topical Terms:

1568676
Systemic scleroderma.

LC Class. No.: RC924.5.S34

Dewey Class. No.: 616.77

Systemic sclerosis
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245 0 0 $a Systemic sclerosis $h [electronic resource] / $c edited by Kazuhiko Takehara, Manabu Fujimoto, Masataka Kuwana.
260 $a Tokyo : $b Springer Japan : $b Imprint: Springer, $c 2016.
300 $a viii, 247 p. : $b ill., digital ; $c 24 cm.
505 0 $a 1 -- Fibrosis: overview 2 -- Autoimmunity in systemic sclerosis: Overview 3 -- Endothelial progenitor cell 4 -- Animal models of systemic sclerosis 5 -- Genetics of Systemic Sclerosis 6 -- Role of the Interleukin-1 Family in the Fibrogenic Phenotype in Systemic Sclerosis 7 -- Interleukin-6 in the Pathogenesis of Systemic Sclerosis 8 -- Epigenetics 9 -- Transforming Growth Factor-ß and Connective Tissue Growth Factor 10 -- Endothelin 11 -- The Role of B cells in Systemic Sclerosis 12 -- Fli1 13 -- Biomarker 14 -- Autoantibodies in Systemic Sclerosis.
520 $a This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma) Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists.
650 0 $a Systemic scleroderma. $3 1568676
650 0 $a Systemic scleroderma $x Research. $3 2183181
650 1 4 $a Medicine & Public Health. $3 890906
650 2 4 $a Dermatology. $3 829009
650 2 4 $a Rheumatology. $3 894494
650 2 4 $a Internal Medicine. $3 858559
700 1 $a Takehara, Kazuhiko. $3 2183178
700 1 $a Fujimoto, Manabu. $3 2183179
700 1 $a Kuwana, Masataka. $3 2183180
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
856 4 0 $u http://dx.doi.org/10.1007/978-4-431-55708-1
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