東華大學圖書館 |

語系: 繁體中文

說明(常見問題)

回圖書館首頁

手機版館藏查詢

登入

回首頁

切換: 標籤 | MARC模式 | ISBD

Clinical trials of antidepressants =...

Katz, Martin M.

FindBook

Google Book

Amazon

博客來

Clinical trials of antidepressants = how changing the model can uncover new, more effective molecules /

紀錄類型:	書目-電子資源 : Monograph/item
正題名/作者:	Clinical trials of antidepressants/ by Martin M. Katz.
其他題名:	how changing the model can uncover new, more effective molecules /
作者:	Katz, Martin M.
出版者:	Cham :Springer International Publishing : : 2016.,
面頁冊數:	xv, 66 p. :ill., digital ;24 cm.
內容註:	Introduction -- Why Now the Need for a New Clinical Trial Model for Antidepressants? -- Reconceptualizing Depression and the Componential-Specific Model of Clinical Trials -- Aims and Basic requirements of Clinical Trials: Conventional and Component-Specific Models -- Methods for Measuring the Components and Profile of Drug Actions: The Multivantaged Approach -- The Component-Specific Model Applied in a Clinical Trial: An Example -- Comparing the Component-Specific Model Directly with the Established Diagnosis-Specific Trial -- Prediction and Shortening the Clinical Trial: Further Advantages of the Component-Specific Model -- The Video Clinical Trial and the VIBES Method -- Conclusions.
Contained By:	Springer eBooks
標題:	Clinical trials - Statistical methods. -
電子資源:	http://dx.doi.org/10.1007/978-3-319-26464-6
ISBN:	9783319264646$q(electronic bk.)

Clinical trials of antidepressants = how changing the model can uncover new, more effective molecules /
Katz, Martin M.

Clinical trials of antidepressantshow changing the model can uncover new, more effective molecules /[electronic resource] :by Martin M. Katz. - Cham :Springer International Publishing :2016. - xv, 66 p. :ill., digital ;24 cm. - SpringerBriefs in psychology,2192-8363. - SpringerBriefs in psychology..

Introduction -- Why Now the Need for a New Clinical Trial Model for Antidepressants? -- Reconceptualizing Depression and the Componential-Specific Model of Clinical Trials -- Aims and Basic requirements of Clinical Trials: Conventional and Component-Specific Models -- Methods for Measuring the Components and Profile of Drug Actions: The Multivantaged Approach -- The Component-Specific Model Applied in a Clinical Trial: An Example -- Comparing the Component-Specific Model Directly with the Established Diagnosis-Specific Trial -- Prediction and Shortening the Clinical Trial: Further Advantages of the Component-Specific Model -- The Video Clinical Trial and the VIBES Method -- Conclusions.

This brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antidepressants and their underlying science. Innovative models are based on a nuanced, neurologically-informed understanding of drug mechanisms and the component cognitive, mood, and behavioral aspects of depression. The book reconceptualizes not only the clinical trial process but the clinical concept of depression itself as essential to bringing pharmaceutical research and development up to date, boosting efficiency and effectiveness, finding new molecules, and reducing waste. Case studies and a review of salient depression scales illustrate the potential benefits of such wide-scale change. Included in the coverage: Why now the need for a new clinical trials model for antidepressants? Aims and basic requirements of clinical trials: conventional and component-specific models. Methods for measuring the components and the profile of drug actions: the multivantaged approach. Achieving the ideal clinical trial: an example of the merged componential and established models. Prediction and shortening the clinical trial. The video clinical trial. Clinical Trials of Antidepressants will interest a varied audience, including clinical investigators, academic and pharmaceutical company scientists, clinical trial organizations, psychiatrists, outpatient physicians, psychotherapists, clinical psychologists, psychology graduate students, medical students, and government agencies such as the FDA.

ISBN: 9783319264646$q(electronic bk.)

Standard No.: 10.1007/978-3-319-26464-6doiSubjects--Topical Terms:

716537
Clinical trials
--Statistical methods.

LC Class. No.: R853.S7

Dewey Class. No.: 610.727

Clinical trials of antidepressants = how changing the model can uncover new, more effective molecules /
LDR:03323nmm a2200337 a 4500 001 2030636
003 DE-He213
005 20160823101705.0
006 m d
007 cr nn 008maaau
008 160908s2016 gw s 0 eng d
020 $a 9783319264646$q(electronic bk.)
020 $a 9783319264639$q(paper)
024 7 $a 10.1007/978-3-319-26464-6 $2 doi
035 $a 978-3-319-26464-6
040 $a GP $c GP
041 0 $a eng
050 4 $a R853.S7
072 7 $a MBNH9 $2 bicssc
072 7 $a PSY003000 $2 bisacsh
072 7 $a MED078000 $2 bisacsh
082 0 4 $a 610.727 $2 23
090 $a R853.S7 $b K19 2016
100 1 $a Katz, Martin M. $3 2182566
245 1 0 $a Clinical trials of antidepressants $h [electronic resource] : $b how changing the model can uncover new, more effective molecules / $c by Martin M. Katz.
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a xv, 66 p. : $b ill., digital ; $c 24 cm.
490 1 $a SpringerBriefs in psychology, $x 2192-8363
505 0 $a Introduction -- Why Now the Need for a New Clinical Trial Model for Antidepressants? -- Reconceptualizing Depression and the Componential-Specific Model of Clinical Trials -- Aims and Basic requirements of Clinical Trials: Conventional and Component-Specific Models -- Methods for Measuring the Components and Profile of Drug Actions: The Multivantaged Approach -- The Component-Specific Model Applied in a Clinical Trial: An Example -- Comparing the Component-Specific Model Directly with the Established Diagnosis-Specific Trial -- Prediction and Shortening the Clinical Trial: Further Advantages of the Component-Specific Model -- The Video Clinical Trial and the VIBES Method -- Conclusions.
520 $a This brief guide takes current clinical trial protocols to task and replaces them with a contemporary framework for improving next-generation antidepressants and their underlying science. Innovative models are based on a nuanced, neurologically-informed understanding of drug mechanisms and the component cognitive, mood, and behavioral aspects of depression. The book reconceptualizes not only the clinical trial process but the clinical concept of depression itself as essential to bringing pharmaceutical research and development up to date, boosting efficiency and effectiveness, finding new molecules, and reducing waste. Case studies and a review of salient depression scales illustrate the potential benefits of such wide-scale change. Included in the coverage: Why now the need for a new clinical trials model for antidepressants? Aims and basic requirements of clinical trials: conventional and component-specific models. Methods for measuring the components and the profile of drug actions: the multivantaged approach. Achieving the ideal clinical trial: an example of the merged componential and established models. Prediction and shortening the clinical trial. The video clinical trial. Clinical Trials of Antidepressants will interest a varied audience, including clinical investigators, academic and pharmaceutical company scientists, clinical trial organizations, psychiatrists, outpatient physicians, psychotherapists, clinical psychologists, psychology graduate students, medical students, and government agencies such as the FDA.
650 0 $a Clinical trials $x Statistical methods. $3 716537
650 0 $a Clinical trials $x Mathematical models. $3 2182567
650 0 $a Antidepressants $x Evaluation. $3 2182568
650 1 4 $a Psychology. $3 519075
650 2 4 $a Health Psychology. $3 894227
710 2 $a SpringerLink (Online service) $3 836513
773 0 $t Springer eBooks
830 0 $a SpringerBriefs in psychology. $3 1568807
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-26464-6
950 $a Behavioral Science and Psychology (Springer-41168)